Matches in SemOpenAlex for { <https://semopenalex.org/work/W1984173811> ?p ?o ?g. }
Showing items 1 to 91 of
91
with 100 items per page.
- W1984173811 endingPage "310" @default.
- W1984173811 startingPage "303" @default.
- W1984173811 abstract "Silibinin is the main isomer of a group of flavanoids extracted from the seeds of the milk thistle weed, a common herb that is widely used to maintain liver health and for the treatment of liver disorders. Silibinin when incubated with human liver microsomes produced one major metabolite and at least two minor metabolites. Tandem mass spectrometry (MS) was used to identify the metabolite structures partially. MS studies confirmed that the major metabolite is demethylated silibinin and the two minor metabolites are mono-hydroxy and di-hydroxy silibinin. The K(m) value for the demethylation shows that silibinin has a strong affinity for the cytochrome P450 enzymes." @default.
- W1984173811 created "2016-06-24" @default.
- W1984173811 creator A5040986818 @default.
- W1984173811 creator A5073806117 @default.
- W1984173811 date "2003-09-01" @default.
- W1984173811 modified "2023-10-14" @default.
- W1984173811 title "Application of liquid chromatography–electrospray ionization-ion trap mass spectrometry to investigate the metabolism of silibinin in human liver microsomes" @default.
- W1984173811 cites W1972901261 @default.
- W1984173811 cites W1974243391 @default.
- W1984173811 cites W1989502324 @default.
- W1984173811 cites W2003227142 @default.
- W1984173811 cites W2018752930 @default.
- W1984173811 cites W2047393168 @default.
- W1984173811 cites W2070829073 @default.
- W1984173811 cites W2154105843 @default.
- W1984173811 cites W2395487467 @default.
- W1984173811 doi "https://doi.org/10.1016/s1570-0232(03)00484-7" @default.
- W1984173811 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12954381" @default.
- W1984173811 hasPublicationYear "2003" @default.
- W1984173811 type Work @default.
- W1984173811 sameAs 1984173811 @default.
- W1984173811 citedByCount "34" @default.
- W1984173811 countsByYear W19841738112013 @default.
- W1984173811 countsByYear W19841738112014 @default.
- W1984173811 countsByYear W19841738112015 @default.
- W1984173811 countsByYear W19841738112017 @default.
- W1984173811 countsByYear W19841738112018 @default.
- W1984173811 countsByYear W19841738112019 @default.
- W1984173811 countsByYear W19841738112020 @default.
- W1984173811 countsByYear W19841738112021 @default.
- W1984173811 countsByYear W19841738112022 @default.
- W1984173811 countsByYear W19841738112023 @default.
- W1984173811 crossrefType "journal-article" @default.
- W1984173811 hasAuthorship W1984173811A5040986818 @default.
- W1984173811 hasAuthorship W1984173811A5073806117 @default.
- W1984173811 hasConcept C104317684 @default.
- W1984173811 hasConcept C150194340 @default.
- W1984173811 hasConcept C162356407 @default.
- W1984173811 hasConcept C181199279 @default.
- W1984173811 hasConcept C185592680 @default.
- W1984173811 hasConcept C190727270 @default.
- W1984173811 hasConcept C202199734 @default.
- W1984173811 hasConcept C2777130413 @default.
- W1984173811 hasConcept C2777477808 @default.
- W1984173811 hasConcept C31827203 @default.
- W1984173811 hasConcept C40684141 @default.
- W1984173811 hasConcept C43617362 @default.
- W1984173811 hasConcept C55493867 @default.
- W1984173811 hasConcept C64489805 @default.
- W1984173811 hasConcept C71924100 @default.
- W1984173811 hasConcept C87644729 @default.
- W1984173811 hasConcept C98274493 @default.
- W1984173811 hasConceptScore W1984173811C104317684 @default.
- W1984173811 hasConceptScore W1984173811C150194340 @default.
- W1984173811 hasConceptScore W1984173811C162356407 @default.
- W1984173811 hasConceptScore W1984173811C181199279 @default.
- W1984173811 hasConceptScore W1984173811C185592680 @default.
- W1984173811 hasConceptScore W1984173811C190727270 @default.
- W1984173811 hasConceptScore W1984173811C202199734 @default.
- W1984173811 hasConceptScore W1984173811C2777130413 @default.
- W1984173811 hasConceptScore W1984173811C2777477808 @default.
- W1984173811 hasConceptScore W1984173811C31827203 @default.
- W1984173811 hasConceptScore W1984173811C40684141 @default.
- W1984173811 hasConceptScore W1984173811C43617362 @default.
- W1984173811 hasConceptScore W1984173811C55493867 @default.
- W1984173811 hasConceptScore W1984173811C64489805 @default.
- W1984173811 hasConceptScore W1984173811C71924100 @default.
- W1984173811 hasConceptScore W1984173811C87644729 @default.
- W1984173811 hasConceptScore W1984173811C98274493 @default.
- W1984173811 hasIssue "2" @default.
- W1984173811 hasLocation W19841738111 @default.
- W1984173811 hasLocation W19841738112 @default.
- W1984173811 hasOpenAccess W1984173811 @default.
- W1984173811 hasPrimaryLocation W19841738111 @default.
- W1984173811 hasRelatedWork W1969076756 @default.
- W1984173811 hasRelatedWork W1988661674 @default.
- W1984173811 hasRelatedWork W1999397561 @default.
- W1984173811 hasRelatedWork W2000133861 @default.
- W1984173811 hasRelatedWork W2020902296 @default.
- W1984173811 hasRelatedWork W2044016383 @default.
- W1984173811 hasRelatedWork W2129939466 @default.
- W1984173811 hasRelatedWork W2383720223 @default.
- W1984173811 hasRelatedWork W2772845628 @default.
- W1984173811 hasRelatedWork W964154261 @default.
- W1984173811 hasVolume "794" @default.
- W1984173811 isParatext "false" @default.
- W1984173811 isRetracted "false" @default.
- W1984173811 magId "1984173811" @default.
- W1984173811 workType "article" @default.