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Matches in SemOpenAlex for { <https://semopenalex.org/work/W1984188081> ?p ?o ?g. }

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• W1984188081 abstract "The FOXM1 forkhead proteins, originally identified as M-phase phosphoproteins, are proliferation-associated transcriptional regulators involved in cell cycle progression, genetic stability and tumorigenesis. Here we demonstrate that Cyclin-dependent kinases regulate the transcriptional activity of FOXM1c. This is independent of an N-terminal negative regulatory domain and of the forkhead DNA binding domain. Instead we mapped the responsive sites in the transactivation domain. A combination of three phosphorylation sites mediates the Cyclin E and Cyclin A/CDK2 effects. Our findings provide evidence for a novel Cyclin E/CDK2 substrate that functions in cell cycle control." @default.
• W1984188081 created "2016-06-24" @default.
• W1984188081 creator A5041462448 @default.
• W1984188081 creator A5065597332 @default.
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• W1984188081 date "2006-02-20" @default.
• W1984188081 modified "2023-10-15" @default.
• W1984188081 title "Regulation of the transcription factor FOXM1c by Cyclin E/CDK2" @default.
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• W1984188081 doi "https://doi.org/10.1016/j.febslet.2006.02.021" @default.
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