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- W1984283036 abstract "To quantitatively detect the nature of balance impairment in patients with progressive supranuclear palsy (PSP) using dynamic posturography. Twenty clinically diagnosed PSP patients (8 women, 12 men; age: 62.1 ± 7.7 years; duration: 2.6 ± 1.3 years) and 20 healthy controls were studied. All subjects were right side dominant. They were evaluated by dynamic posturography (Biodex, USA). The measurements included (i) balance indices: ability to control balance in all directions (overall balance index, OBI), front to back (anterior–posterior index, API) and side-to-side (medio-lateral index, MLI), and (ii) the limits of stability (LOS) in 8 directions: forward (FW), backward (BW), right (RT), left (LT), forward-right (FW-RT), forward-left (FW-LT), backward-right (BW-RT) and backward-left (BW-LT). Compared to controls, patients showed significantly higher OBI (p < 0.001), API (p = 0.003) and MLI (p < 0.001), implying impaired balance. The total LOS score was significantly lower (implying poor stability) in PSP than in controls (18.3 ± 7.3 vs. 28.4 ± 8.5, p < 0.001). Patients took significantly longer time to complete LOS test (262.7 ± 33.0 s vs. 135.4 ± 20.6 s, p < 0.001). Direction-wise analysis showed that PSP patients had significantly lower LOS scores in FW, BW, RT, FW-RT, BW-RT and BW-LT directions compared to controls. However the scores in LT and FW-LT did not differ significantly. PSP patients showed impaired balance indices and decreased overall LOS compared to controls. Though LOS is affected in PSP, the scores in the left (non-dominant side) and forward-left (non-dominant forward diagonal) directions were preserved." @default.
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- W1984283036 date "2012-04-01" @default.
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- W1984283036 title "Direction specific preserved limits of stability in early progressive supranuclear palsy: A dynamic posturographic study" @default.
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- W1984283036 doi "https://doi.org/10.1016/j.gaitpost.2011.12.012" @default.
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