FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1984288164> ?p ?o ?g. }

• W1984288164 endingPage "2360" @default.
• W1984288164 startingPage "2360" @default.
• W1984288164 abstract "Purpose.: To model the photochemical kinetics of corneal cross-linking with riboflavin (Rf) and confirm the model through measured oxygen concentration experiments under varying energy input conditions by UV-A irradiance and temperature modulation in ex vivo porcine cornea. Methods.: A theoretical model was developed to describe the corneal cross-linking photochemical kinetics of Rf. After instillation with drops of Rf solution in distilled water, de-epithelialized porcine corneas were exposed to 365-nm ultraviolet light (UV-A) under varying irradiance and temperature. Oxygen concentration in the cornea at a known depth was monitored during UV-A illumination with a dissolved oxygen fiberoptic microsensor. Data from the oxygen experiments were used to confirm the model. Results.: On the basis of the known chemical reactions and diffusion rates of Rf and oxygen into the cornea, the authors developed a theoretical model consistent with corneal oxygen consumption experimental results during UV-A irradiation under different conditions. Oxygen concentration in the cornea is modulated by UV-A irradiance and temperature and quickly decreased at the beginning of UV-A exposure. The time-dependence of both Type-I and Type-II photochemical mechanisms in corneal cross-linking with Rf are discussed. Conclusions.: Using a chemical kinetics modeling approach, the authors developed a simple model that is in agreement with their experimental results on oxygen consumption in the cornea during corneal cross-linking with Rf. It is suggested that the main photochemical kinetics mechanism is the direct interaction between Rf triplets and reactive groups of corneal proteins, which leads to the cross-linking of the proteins mainly through radical reactions." @default.
• W1984288164 created "2016-06-24" @default.
• W1984288164 creator A5046597088 @default.
• W1984288164 creator A5058855216 @default.
• W1984288164 creator A5065788139 @default.
• W1984288164 creator A5067031314 @default.
• W1984288164 date "2012-04-30" @default.
• W1984288164 modified "2023-10-14" @default.
• W1984288164 title "Photochemical Kinetics of Corneal Cross-Linking with Riboflavin" @default.
• W1984288164 cites W106410417 @default.
• W1984288164 cites W1549749615 @default.
• W1984288164 cites W1584878126 @default.
• W1984288164 cites W1606467807 @default.
• W1984288164 cites W1933515027 @default.
• W1984288164 cites W1968177771 @default.
• W1984288164 cites W1971412552 @default.
• W1984288164 cites W1973009377 @default.
• W1984288164 cites W1983301059 @default.
• W1984288164 cites W1988219410 @default.
• W1984288164 cites W1991185185 @default.
• W1984288164 cites W2000544973 @default.
• W1984288164 cites W2001530049 @default.
• W1984288164 cites W2002534688 @default.
• W1984288164 cites W2005181129 @default.
• W1984288164 cites W2023014699 @default.
• W1984288164 cites W2029548502 @default.
• W1984288164 cites W2049705176 @default.
• W1984288164 cites W2053191139 @default.
• W1984288164 cites W2058764661 @default.
• W1984288164 cites W2060477052 @default.
• W1984288164 cites W2065132583 @default.
• W1984288164 cites W2068396360 @default.
• W1984288164 cites W2081257957 @default.
• W1984288164 cites W2082521649 @default.
• W1984288164 cites W2088173043 @default.
• W1984288164 cites W2089488785 @default.
• W1984288164 cites W2091656924 @default.
• W1984288164 cites W2113430923 @default.
• W1984288164 cites W2123707760 @default.
• W1984288164 cites W2131247133 @default.
• W1984288164 cites W2155644024 @default.
• W1984288164 cites W2167005887 @default.
• W1984288164 cites W2123593705 @default.
• W1984288164 cites W2435357293 @default.
• W1984288164 doi "https://doi.org/10.1167/iovs.11-9385" @default.
• W1984288164 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22427580" @default.
• W1984288164 hasPublicationYear "2012" @default.
• W1984288164 type Work @default.
• W1984288164 sameAs 1984288164 @default.
• W1984288164 citedByCount "230" @default.
• W1984288164 countsByYear W19842881642012 @default.
• W1984288164 countsByYear W19842881642013 @default.
• W1984288164 countsByYear W19842881642014 @default.
• W1984288164 countsByYear W19842881642015 @default.
• W1984288164 countsByYear W19842881642016 @default.
• W1984288164 countsByYear W19842881642017 @default.
• W1984288164 countsByYear W19842881642018 @default.
• W1984288164 countsByYear W19842881642019 @default.
• W1984288164 countsByYear W19842881642020 @default.
• W1984288164 countsByYear W19842881642021 @default.
• W1984288164 countsByYear W19842881642022 @default.
• W1984288164 countsByYear W19842881642023 @default.
• W1984288164 crossrefType "journal-article" @default.
• W1984288164 hasAuthorship W1984288164A5046597088 @default.
• W1984288164 hasAuthorship W1984288164A5058855216 @default.
• W1984288164 hasAuthorship W1984288164A5065788139 @default.
• W1984288164 hasAuthorship W1984288164A5067031314 @default.
• W1984288164 hasBestOaLocation W19842881641 @default.
• W1984288164 hasConcept C111337013 @default.
• W1984288164 hasConcept C113196181 @default.
• W1984288164 hasConcept C120665830 @default.
• W1984288164 hasConcept C121332964 @default.
• W1984288164 hasConcept C148898269 @default.
• W1984288164 hasConcept C16005928 @default.
• W1984288164 hasConcept C178790620 @default.
• W1984288164 hasConcept C185544564 @default.
• W1984288164 hasConcept C185592680 @default.
• W1984288164 hasConcept C192562407 @default.
• W1984288164 hasConcept C2776155809 @default.
• W1984288164 hasConcept C2776798109 @default.
• W1984288164 hasConcept C2776882836 @default.
• W1984288164 hasConcept C2779429693 @default.
• W1984288164 hasConcept C3017420807 @default.
• W1984288164 hasConcept C36663273 @default.
• W1984288164 hasConcept C43617362 @default.
• W1984288164 hasConcept C46423501 @default.
• W1984288164 hasConcept C49040817 @default.
• W1984288164 hasConcept C540031477 @default.
• W1984288164 hasConcept C55493867 @default.
• W1984288164 hasConcept C62520636 @default.
• W1984288164 hasConcept C71924100 @default.
• W1984288164 hasConcept C75473681 @default.
• W1984288164 hasConcept C89169090 @default.
• W1984288164 hasConceptScore W1984288164C111337013 @default.
• W1984288164 hasConceptScore W1984288164C113196181 @default.
• W1984288164 hasConceptScore W1984288164C120665830 @default.
• W1984288164 hasConceptScore W1984288164C121332964 @default.
• W1984288164 hasConceptScore W1984288164C148898269 @default.

• next