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• W1984314109 abstract "Objective Coronary artery calcification has been associated with higher mortality in coronary artery disease and chronic kidney disease. This study aimed to correlate coronary artery calcification score (CACS) with all-cause and cardiovascular mortalities in hemodialysis (HD) patients. Design, Setting, Subjects A survival analysis was conducted in 200 HD patients. CACS was assessed by multidetector-row computed tomography and stratified as tertiles: group 1 (0∼105 U), group 2 (110∼1067 U), and group 3 (1094∼15481 U). The duration of follow-up was 7 years and 4 months. Kaplan–Meier method and Cox proportional hazard analysis adjusted for age and HD duration were performed to examine the impact of CACS on survival. Main Outcome Measure All-cause and cardiovascular mortalities were measured. Results The cumulative all-cause and cardiovascular mortalities of group 1 were significantly lower than those of groups 2 and 3 (all-cause mortality: 7.6% vs. 43.3% and 52.2%, respectively, cardiovascular mortality: 3.0% vs. 22.4% and 26.9%, respectively). Cox proportional hazard analysis adjusted for age and HD duration revealed that all-cause and cardiovascular mortalities of group 1 were significantly lower than those of groups 2 and 3. Conclusion CACS is helpful to predict prognosis of HD patients independently of age and HD duration. Coronary artery calcification has been associated with higher mortality in coronary artery disease and chronic kidney disease. This study aimed to correlate coronary artery calcification score (CACS) with all-cause and cardiovascular mortalities in hemodialysis (HD) patients. A survival analysis was conducted in 200 HD patients. CACS was assessed by multidetector-row computed tomography and stratified as tertiles: group 1 (0∼105 U), group 2 (110∼1067 U), and group 3 (1094∼15481 U). The duration of follow-up was 7 years and 4 months. Kaplan–Meier method and Cox proportional hazard analysis adjusted for age and HD duration were performed to examine the impact of CACS on survival. All-cause and cardiovascular mortalities were measured. The cumulative all-cause and cardiovascular mortalities of group 1 were significantly lower than those of groups 2 and 3 (all-cause mortality: 7.6% vs. 43.3% and 52.2%, respectively, cardiovascular mortality: 3.0% vs. 22.4% and 26.9%, respectively). Cox proportional hazard analysis adjusted for age and HD duration revealed that all-cause and cardiovascular mortalities of group 1 were significantly lower than those of groups 2 and 3. CACS is helpful to predict prognosis of HD patients independently of age and HD duration." @default.
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• W1984314109 date "2012-01-01" @default.
• W1984314109 modified "2023-09-23" @default.
• W1984314109 title "Coronary Artery Calcification Score is Associated With Mortality in Japanese Hemodialysis Patients" @default.
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• W1984314109 doi "https://doi.org/10.1053/j.jrn.2011.10.024" @default.
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