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- W1984364069 abstract "Imbalance of important potential confounders between groups at baseline has always been one of the major challenges of randomized control trials (RCTs). Taves argues that minimization using the new rank-minimization approach should replace randomization in all clinical trials and be accepted as the platinum standard. Acceptance of minimization has been slow because of its vulnerability to selection bias, as well as uncertainty about how to analyze the data. Taves argues that these can be addressed using Rank-Minimization; thisnew algorithm, like other algorithms for minimization, uses any number of patientcharacteristics to determine the optimum balance in the treatment groups following a tentative placement of thesubject." @default.
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- W1984364069 date "2012-01-01" @default.
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- W1984364069 title "Should minimization replace randomization in all clinical trials?" @default.
- W1984364069 cites W2079351763 @default.
- W1984364069 doi "https://doi.org/10.1016/j.jclinepi.2011.10.011" @default.
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