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- W1984438023 abstract "Both pleiotropy and linkage were examined as possible explanations for the fixation of the Hbb s allele in the six Large lines of a population of mice divergently selected for six-week body weight (six replicates in each direction and six controls). A survey of over 1200 individuals in the lines still segregating at the Hbb locus excluded pleiotropy as a possible explanation. The results showed a nonsignificant effect of haemoglobin genotype on body weight. The linkage relationship of the Hbb locus was examined using a backcross mating system. The Hbb s c + region (chromosome 7) of a Large line was backcrossed into its corresponding Small line (Hbb d c). The resultant difference in body weight between the two segregants (Hbb s c + /Hbb d c; Hbb d c/Hbb d c) was measured. The results suggested linkage as the most plausible explanation for the fixation of the Hbb s allele in the six Large lines." @default.
- W1984438023 created "2016-06-24" @default.
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- W1984438023 date "1976-09-01" @default.
- W1984438023 modified "2023-09-24" @default.
- W1984438023 title "THE GENETIC RELATIONSHIP BETWEEN THE Hbb LOCUS AND BODY SIZE IN A POPULATION OF MICE DIVERGENTLY SELECTED FOR SIX-WEEK BODY WEIGHT" @default.
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- W1984438023 doi "https://doi.org/10.1139/g76-064" @default.
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