FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1984460413> ?p ?o ?g. }

• W1984460413 endingPage "5996" @default.
• W1984460413 startingPage "5989" @default.
• W1984460413 abstract "Abstract BACKGROUND: The effect of body mass index (BMI) on the treatment outcomes of children with acute myeloid leukemia (AML) is unclear and needs further evaluation. METHODS: Children with AML (n = 314) who were enrolled in 4 consecutive St. Jude protocols were grouped according to BMI (underweight, <5th percentile; healthy weight, 5th to 85th percentile; and overweight/obese, ≥85th percentile). RESULTS: Twenty‐five patients (8%) were underweight, 86 patients (27.4%) were overweight/obese, and 203 patients (64.6%) had healthy weight. The 5‐year overall survival rate of overweight/obese patients (46.5% ± 7.3%) was lower than the rate of patients with healthy weight (67.1% ± 4.3%; P < .001); underweight patients also tended to have lower survival rates (50.6% ± 10.7%; P = .18). In a multivariable analysis that was adjusted for age, leukocyte count, French‐American‐British classification, and study protocols, patients with healthy weight had the best survival rate among the 3 groups ( P = .01). When BMI was considered as continuous variable, patients with lower or higher BMI percentiles had worse survival ( P = .03). There was no difference in the occurrence of induction failure or relapse among BMI groups, although underweight and overweight/obese patients had a significantly higher cumulative incidence of treatment‐related mortality, especially because of infection ( P = .009). CONCLUSIONS: An unhealthy BMI was associated with worse survival and more treatment‐related mortality in children with AML. Meticulous supportive care with nutritional support and education, infection prophylaxis, and detailed laboratory and physical examination is required for these patients. These measures, together with pharmacokinetics‐guided chemotherapy dosing, may improve outcome. Cancer 2012. © 2012 American Cancer Society." @default.
• W1984460413 created "2016-06-24" @default.
• W1984460413 creator A5006746068 @default.
• W1984460413 creator A5008374158 @default.
• W1984460413 creator A5011622752 @default.
• W1984460413 creator A5040348744 @default.
• W1984460413 creator A5050655836 @default.
• W1984460413 creator A5050942040 @default.
• W1984460413 creator A5064611054 @default.
• W1984460413 creator A5065331155 @default.
• W1984460413 creator A5065634145 @default.
• W1984460413 creator A5069687533 @default.
• W1984460413 creator A5070351551 @default.
• W1984460413 creator A5075827511 @default.
• W1984460413 creator A5075936752 @default.
• W1984460413 creator A5086250633 @default.
• W1984460413 date "2012-05-30" @default.
• W1984460413 modified "2023-10-18" @default.
• W1984460413 title "Effect of body mass index on the outcome of children with acute myeloid leukemia" @default.
• W1984460413 cites W1847612791 @default.
• W1984460413 cites W1971445485 @default.
• W1984460413 cites W1992371348 @default.
• W1984460413 cites W2004467408 @default.
• W1984460413 cites W2010032806 @default.
• W1984460413 cites W2018910795 @default.
• W1984460413 cites W2023392000 @default.
• W1984460413 cites W2028275121 @default.
• W1984460413 cites W2038252730 @default.
• W1984460413 cites W2041282815 @default.
• W1984460413 cites W2045525494 @default.
• W1984460413 cites W2054621363 @default.
• W1984460413 cites W2068523760 @default.
• W1984460413 cites W2073140442 @default.
• W1984460413 cites W2093825731 @default.
• W1984460413 cites W2109703672 @default.
• W1984460413 cites W2118250079 @default.
• W1984460413 cites W2121548187 @default.
• W1984460413 cites W2129513608 @default.
• W1984460413 cites W2130064617 @default.
• W1984460413 cites W2132122697 @default.
• W1984460413 cites W2132243715 @default.
• W1984460413 cites W2135003681 @default.
• W1984460413 cites W2143757227 @default.
• W1984460413 cites W2334351177 @default.
• W1984460413 cites W4293241248 @default.
• W1984460413 doi "https://doi.org/10.1002/cncr.27640" @default.
• W1984460413 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3434283" @default.
• W1984460413 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22648558" @default.
• W1984460413 hasPublicationYear "2012" @default.
• W1984460413 type Work @default.
• W1984460413 sameAs 1984460413 @default.
• W1984460413 citedByCount "56" @default.
• W1984460413 countsByYear W19844604132013 @default.
• W1984460413 countsByYear W19844604132014 @default.
• W1984460413 countsByYear W19844604132015 @default.
• W1984460413 countsByYear W19844604132016 @default.
• W1984460413 countsByYear W19844604132017 @default.
• W1984460413 countsByYear W19844604132018 @default.
• W1984460413 countsByYear W19844604132019 @default.
• W1984460413 countsByYear W19844604132020 @default.
• W1984460413 countsByYear W19844604132021 @default.
• W1984460413 countsByYear W19844604132022 @default.
• W1984460413 countsByYear W19844604132023 @default.
• W1984460413 crossrefType "journal-article" @default.
• W1984460413 hasAuthorship W1984460413A5006746068 @default.
• W1984460413 hasAuthorship W1984460413A5008374158 @default.
• W1984460413 hasAuthorship W1984460413A5011622752 @default.
• W1984460413 hasAuthorship W1984460413A5040348744 @default.
• W1984460413 hasAuthorship W1984460413A5050655836 @default.
• W1984460413 hasAuthorship W1984460413A5050942040 @default.
• W1984460413 hasAuthorship W1984460413A5064611054 @default.
• W1984460413 hasAuthorship W1984460413A5065331155 @default.
• W1984460413 hasAuthorship W1984460413A5065634145 @default.
• W1984460413 hasAuthorship W1984460413A5069687533 @default.
• W1984460413 hasAuthorship W1984460413A5070351551 @default.
• W1984460413 hasAuthorship W1984460413A5075827511 @default.
• W1984460413 hasAuthorship W1984460413A5075936752 @default.
• W1984460413 hasAuthorship W1984460413A5086250633 @default.
• W1984460413 hasBestOaLocation W19844604131 @default.
• W1984460413 hasConcept C105795698 @default.
• W1984460413 hasConcept C120665830 @default.
• W1984460413 hasConcept C121332964 @default.
• W1984460413 hasConcept C122048520 @default.
• W1984460413 hasConcept C126322002 @default.
• W1984460413 hasConcept C179755657 @default.
• W1984460413 hasConcept C187212893 @default.
• W1984460413 hasConcept C2776283816 @default.
• W1984460413 hasConcept C2778729363 @default.
• W1984460413 hasConcept C2780221984 @default.
• W1984460413 hasConcept C2780586474 @default.
• W1984460413 hasConcept C2781121325 @default.
• W1984460413 hasConcept C33923547 @default.
• W1984460413 hasConcept C511355011 @default.
• W1984460413 hasConcept C61511704 @default.
• W1984460413 hasConcept C71924100 @default.
• W1984460413 hasConceptScore W1984460413C105795698 @default.
• W1984460413 hasConceptScore W1984460413C120665830 @default.
• W1984460413 hasConceptScore W1984460413C121332964 @default.

• next