FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1984511428> ?p ?o ?g. }

• W1984511428 endingPage "208" @default.
• W1984511428 startingPage "201" @default.
• W1984511428 abstract "Hypersensitivity pneumonitis (HP) is traditionally divided on clinical grounds into acute, subacute, and chronic stages. Most biopsy specimens come from patients in the subacute stage, in which there is a relatively mild, usually peribronchiolar, chronic interstitial inflammatory infiltrate, accompanied in most cases by poorly formed interstitial granulomas or isolated giant cells. However, the pathologic features in the chronic, ie, fibrotic stage, are poorly defined in the literature. These features are important to recognize because the chronic stage of HP is often associated with a poor prognosis. We reviewed 13 cases of chronic HP. Where information was available, exposures to the sensitizing agent had generally occurred over a long period of time. Three patterns of fibrosis were seen: 1) predominantly peripheral fibrosis in a patchy pattern with architectural distortion and fibroblast foci resembling, microscopically, usual interstitial pneumonia (UIP); 2) relatively homogeneous linear fibrosis resembling fibrotic nonspecific interstitial pneumonia (NSIP); and 3) irregular predominantly peribronchiolar fibrosis. In some instances, mixtures of the UIP-like and peribronchiolar patterns were found. In all cases, the presence of scattered poorly formed granulomas, or isolated interstitial giant cells, or sometimes only Schaumann bodies indicated the correct diagnosis. In 7 cases, areas of typical subacute HP were present as well. High-resolution CT scans showed variable patterns ranging from severe fibrosis, in some instances with an upper zone predominance, to predominantly ground glass opacities with peripheral reticulation. We conclude that, at the level of morphology, chronic HP may closely mimic UIP or fibrotic NSIP. If no areas of subacute HP are evident, the presence of isolated giant cells, poorly formed granulomas, or Schaumann bodies is crucial to arriving at the correct diagnosis, and the finding of peribronchiolar fibrosis may be helpful. Despite the presence of extensive fibrosis, some patients responded to removal from exposure and steroid therapy." @default.
• W1984511428 created "2016-06-24" @default.
• W1984511428 creator A5009947587 @default.
• W1984511428 creator A5022269910 @default.
• W1984511428 creator A5042122214 @default.
• W1984511428 creator A5085606802 @default.
• W1984511428 date "2006-02-01" @default.
• W1984511428 modified "2023-09-25" @default.
• W1984511428 title "Chronic Hypersensitivity Pneumonitis" @default.
• W1984511428 cites W1966320808 @default.
• W1984511428 cites W1976064041 @default.
• W1984511428 cites W1982783659 @default.
• W1984511428 cites W1982864372 @default.
• W1984511428 cites W1992712552 @default.
• W1984511428 cites W1998578092 @default.
• W1984511428 cites W2001054069 @default.
• W1984511428 cites W2002118427 @default.
• W1984511428 cites W2013117188 @default.
• W1984511428 cites W2037010539 @default.
• W1984511428 cites W2064651440 @default.
• W1984511428 cites W2067864764 @default.
• W1984511428 cites W2073939284 @default.
• W1984511428 cites W2076131946 @default.
• W1984511428 cites W2076467354 @default.
• W1984511428 cites W2083983188 @default.
• W1984511428 cites W2129655600 @default.
• W1984511428 cites W2133163505 @default.
• W1984511428 cites W2137942552 @default.
• W1984511428 cites W2141364182 @default.
• W1984511428 cites W2161291663 @default.
• W1984511428 cites W2317546260 @default.
• W1984511428 cites W2328859138 @default.
• W1984511428 cites W4211146609 @default.
• W1984511428 doi "https://doi.org/10.1097/01.pas.0000184806.38037.3c" @default.
• W1984511428 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16434894" @default.
• W1984511428 hasPublicationYear "2006" @default.
• W1984511428 type Work @default.
• W1984511428 sameAs 1984511428 @default.
• W1984511428 citedByCount "169" @default.
• W1984511428 countsByYear W19845114282012 @default.
• W1984511428 countsByYear W19845114282013 @default.
• W1984511428 countsByYear W19845114282014 @default.
• W1984511428 countsByYear W19845114282015 @default.
• W1984511428 countsByYear W19845114282016 @default.
• W1984511428 countsByYear W19845114282017 @default.
• W1984511428 countsByYear W19845114282018 @default.
• W1984511428 countsByYear W19845114282019 @default.
• W1984511428 countsByYear W19845114282020 @default.
• W1984511428 countsByYear W19845114282021 @default.
• W1984511428 countsByYear W19845114282022 @default.
• W1984511428 countsByYear W19845114282023 @default.
• W1984511428 crossrefType "journal-article" @default.
• W1984511428 hasAuthorship W1984511428A5009947587 @default.
• W1984511428 hasAuthorship W1984511428A5022269910 @default.
• W1984511428 hasAuthorship W1984511428A5042122214 @default.
• W1984511428 hasAuthorship W1984511428A5085606802 @default.
• W1984511428 hasConcept C126322002 @default.
• W1984511428 hasConcept C142724271 @default.
• W1984511428 hasConcept C2775934546 @default.
• W1984511428 hasConcept C2777134676 @default.
• W1984511428 hasConcept C2777405647 @default.
• W1984511428 hasConcept C2777714996 @default.
• W1984511428 hasConcept C2780559512 @default.
• W1984511428 hasConcept C2781244666 @default.
• W1984511428 hasConcept C2994364436 @default.
• W1984511428 hasConcept C71924100 @default.
• W1984511428 hasConcept C77076574 @default.
• W1984511428 hasConceptScore W1984511428C126322002 @default.
• W1984511428 hasConceptScore W1984511428C142724271 @default.
• W1984511428 hasConceptScore W1984511428C2775934546 @default.
• W1984511428 hasConceptScore W1984511428C2777134676 @default.
• W1984511428 hasConceptScore W1984511428C2777405647 @default.
• W1984511428 hasConceptScore W1984511428C2777714996 @default.
• W1984511428 hasConceptScore W1984511428C2780559512 @default.
• W1984511428 hasConceptScore W1984511428C2781244666 @default.
• W1984511428 hasConceptScore W1984511428C2994364436 @default.
• W1984511428 hasConceptScore W1984511428C71924100 @default.
• W1984511428 hasConceptScore W1984511428C77076574 @default.
• W1984511428 hasIssue "2" @default.
• W1984511428 hasLocation W19845114281 @default.
• W1984511428 hasLocation W19845114282 @default.
• W1984511428 hasOpenAccess W1984511428 @default.
• W1984511428 hasPrimaryLocation W19845114281 @default.
• W1984511428 hasRelatedWork W1984265631 @default.
• W1984511428 hasRelatedWork W1984511428 @default.
• W1984511428 hasRelatedWork W2006282566 @default.
• W1984511428 hasRelatedWork W2090522092 @default.
• W1984511428 hasRelatedWork W2096257246 @default.
• W1984511428 hasRelatedWork W2415410653 @default.
• W1984511428 hasRelatedWork W2441120022 @default.
• W1984511428 hasRelatedWork W2472837931 @default.
• W1984511428 hasRelatedWork W3216664982 @default.
• W1984511428 hasRelatedWork W4366350943 @default.
• W1984511428 hasVolume "30" @default.
• W1984511428 isParatext "false" @default.
• W1984511428 isRetracted "false" @default.
• W1984511428 magId "1984511428" @default.
• W1984511428 workType "article" @default.