Matches in SemOpenAlex for { <https://semopenalex.org/work/W1984554313> ?p ?o ?g. }
- W1984554313 abstract "Metabotropic glutamate (mGlu) and cannabinoid receptors are G-protein coupled receptors which have shown synaptic co-operation through small lipid messengers in the central nervous system (CNS). A functional interaction between these two receptor families could have a relevant potential in the treatment of CNS disorders, including chronic pain. Indeed, both mGlu and cannabinoid receptors play a crucial role in the neurobiology of pain and their simultaneous manipulation could lead to novel strategies in pain management. In particular, as both mGlu and cannabinoid receptors have been found in the periaqueductal gray (PAG), a crucial station in the pain modulatory system, these receptors could be a substrate for producing analgesia at this level. In this review we aim to briefly illustrate the role of mGlu and can-nabinoid receptors in controlling nociceptive processes, some points of convergence, and their functional interaction in pain processing. Further insights into this functional linkage between the mGlu and cannabinoid receptors could pave the way to a new strategy for pain relief, such as a drug cocktail acting on cannabinoid/metabotropic glutamate receptors." @default.
- W1984554313 created "2016-06-24" @default.
- W1984554313 creator A5007203413 @default.
- W1984554313 creator A5046208271 @default.
- W1984554313 creator A5047470778 @default.
- W1984554313 creator A5061433350 @default.
- W1984554313 creator A5065084877 @default.
- W1984554313 date "2006-07-01" @default.
- W1984554313 modified "2023-09-25" @default.
- W1984554313 title "Metabotropic Glutamate and Cannabinoid Receptor Crosstalk in Periaqueductal Grey Pain Processing" @default.
- W1984554313 cites W1570505030 @default.
- W1984554313 cites W1600528148 @default.
- W1984554313 cites W1742235708 @default.
- W1984554313 cites W1810539664 @default.
- W1984554313 cites W1836729582 @default.
- W1984554313 cites W1838045633 @default.
- W1984554313 cites W1907919347 @default.
- W1984554313 cites W1909460102 @default.
- W1984554313 cites W1916850619 @default.
- W1984554313 cites W1936828440 @default.
- W1984554313 cites W1968426375 @default.
- W1984554313 cites W1968446992 @default.
- W1984554313 cites W1969498997 @default.
- W1984554313 cites W1980122275 @default.
- W1984554313 cites W1982186440 @default.
- W1984554313 cites W1984165143 @default.
- W1984554313 cites W1991050464 @default.
- W1984554313 cites W1992279992 @default.
- W1984554313 cites W1995048478 @default.
- W1984554313 cites W1995838237 @default.
- W1984554313 cites W1999145375 @default.
- W1984554313 cites W2005702675 @default.
- W1984554313 cites W2007163794 @default.
- W1984554313 cites W2007715028 @default.
- W1984554313 cites W2009864778 @default.
- W1984554313 cites W2010086382 @default.
- W1984554313 cites W2012824611 @default.
- W1984554313 cites W2016026978 @default.
- W1984554313 cites W2018040597 @default.
- W1984554313 cites W2018906747 @default.
- W1984554313 cites W2019946314 @default.
- W1984554313 cites W2024095921 @default.
- W1984554313 cites W2029775732 @default.
- W1984554313 cites W2030777873 @default.
- W1984554313 cites W2037043198 @default.
- W1984554313 cites W2037127967 @default.
- W1984554313 cites W2038085549 @default.
- W1984554313 cites W2038329036 @default.
- W1984554313 cites W2038429859 @default.
- W1984554313 cites W2040944816 @default.
- W1984554313 cites W2044879864 @default.
- W1984554313 cites W2048760742 @default.
- W1984554313 cites W2050975846 @default.
- W1984554313 cites W2052081801 @default.
- W1984554313 cites W2054723059 @default.
- W1984554313 cites W2057515228 @default.
- W1984554313 cites W2059977407 @default.
- W1984554313 cites W2060694966 @default.
- W1984554313 cites W2061533116 @default.
- W1984554313 cites W2063102563 @default.
- W1984554313 cites W2064128689 @default.
- W1984554313 cites W2065038050 @default.
- W1984554313 cites W2065201875 @default.
- W1984554313 cites W2067795636 @default.
- W1984554313 cites W2070535004 @default.
- W1984554313 cites W2070736467 @default.
- W1984554313 cites W2079403841 @default.
- W1984554313 cites W2083586967 @default.
- W1984554313 cites W2084258351 @default.
- W1984554313 cites W2084366301 @default.
- W1984554313 cites W2085436487 @default.
- W1984554313 cites W2085734079 @default.
- W1984554313 cites W2090783774 @default.
- W1984554313 cites W2091061257 @default.
- W1984554313 cites W2091679239 @default.
- W1984554313 cites W2092767025 @default.
- W1984554313 cites W2095577553 @default.
- W1984554313 cites W2098443650 @default.
- W1984554313 cites W2102871973 @default.
- W1984554313 cites W2109070839 @default.
- W1984554313 cites W2110551626 @default.
- W1984554313 cites W2124248227 @default.
- W1984554313 cites W2130435998 @default.
- W1984554313 cites W2133702956 @default.
- W1984554313 cites W2136880546 @default.
- W1984554313 cites W2137459553 @default.
- W1984554313 cites W2139984207 @default.
- W1984554313 cites W2143939545 @default.
- W1984554313 cites W2145087250 @default.
- W1984554313 cites W2146141725 @default.
- W1984554313 cites W2149931140 @default.
- W1984554313 cites W2150033209 @default.
- W1984554313 cites W2154546113 @default.
- W1984554313 cites W2159484326 @default.
- W1984554313 cites W2160725099 @default.
- W1984554313 cites W2166086438 @default.
- W1984554313 cites W2256576734 @default.
- W1984554313 cites W2271386257 @default.
- W1984554313 cites W2495324539 @default.
- W1984554313 cites W38310539 @default.