Matches in SemOpenAlex for { <https://semopenalex.org/work/W1984587636> ?p ?o ?g. }
Showing items 1 to 75 of
75
with 100 items per page.
- W1984587636 abstract "Ifosfamide was administered to 21 patients with recurrent or disseminated lung cancer at a dose of 4.0 gm/M2 iv every 3 weeks. The response rate was 33% with an additional 14% showing no response or stable disease. At a dose of 1.2 gm/M2 daily for 5 days every 4 weeks, 57% of 14 patients responded with 35% showing no response or stable disease. The majority of the patients (28) had epidermoid carcinoma. Two (7%) had complete response with 9 (32%) showing partial responses. Other responses included 1/2 oat cell carcinomas and 3/6 large cell undifferentiated carcinomas. Toxicity was equal in both regimens for nausea, vomiting, increased serum LDH and neutropenia but the 5 day program had significantly less hemorrhagic cystitis. Survival was greatly influenced by response. There was no statistical difference in overall length of response between responders and the non responding/stable disease patients. But these two groups had a very significant survival advantage when compared to those patients with increasing disease. Similarly, there was a significant improvement in response duration for the low dosage regimen. Therefore, the low dose 5 day regimen is recommended because of its response rate, it has less hemorrhagic cystitis and it has better patient acceptance in that it can be given as an outpatient and does not require a Foley catheter." @default.
- W1984587636 created "2016-06-24" @default.
- W1984587636 creator A5014326727 @default.
- W1984587636 creator A5015827324 @default.
- W1984587636 creator A5016124471 @default.
- W1984587636 creator A5040216740 @default.
- W1984587636 creator A5066591840 @default.
- W1984587636 date "1978-05-01" @default.
- W1984587636 modified "2023-10-05" @default.
- W1984587636 title "Ifosfamide in the treatment of recurrent or disseminated lung cancerA phase II study of two dose schedules" @default.
- W1984587636 cites W2143594378 @default.
- W1984587636 cites W624430683 @default.
- W1984587636 doi "https://doi.org/10.1002/1097-0142(197805)41:5<1715::aid-cncr2820410510>3.0.co;2-x" @default.
- W1984587636 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/206339" @default.
- W1984587636 hasPublicationYear "1978" @default.
- W1984587636 type Work @default.
- W1984587636 sameAs 1984587636 @default.
- W1984587636 citedByCount "43" @default.
- W1984587636 crossrefType "journal-article" @default.
- W1984587636 hasAuthorship W1984587636A5014326727 @default.
- W1984587636 hasAuthorship W1984587636A5015827324 @default.
- W1984587636 hasAuthorship W1984587636A5016124471 @default.
- W1984587636 hasAuthorship W1984587636A5040216740 @default.
- W1984587636 hasAuthorship W1984587636A5066591840 @default.
- W1984587636 hasBestOaLocation W19845876361 @default.
- W1984587636 hasConcept C126322002 @default.
- W1984587636 hasConcept C141071460 @default.
- W1984587636 hasConcept C2776256026 @default.
- W1984587636 hasConcept C2776694085 @default.
- W1984587636 hasConcept C2776755627 @default.
- W1984587636 hasConcept C2777063308 @default.
- W1984587636 hasConcept C2777506904 @default.
- W1984587636 hasConcept C2777600175 @default.
- W1984587636 hasConcept C2778119113 @default.
- W1984587636 hasConcept C2778822529 @default.
- W1984587636 hasConcept C2780580376 @default.
- W1984587636 hasConcept C2780852908 @default.
- W1984587636 hasConcept C2781413609 @default.
- W1984587636 hasConcept C29730261 @default.
- W1984587636 hasConcept C71924100 @default.
- W1984587636 hasConcept C90924648 @default.
- W1984587636 hasConceptScore W1984587636C126322002 @default.
- W1984587636 hasConceptScore W1984587636C141071460 @default.
- W1984587636 hasConceptScore W1984587636C2776256026 @default.
- W1984587636 hasConceptScore W1984587636C2776694085 @default.
- W1984587636 hasConceptScore W1984587636C2776755627 @default.
- W1984587636 hasConceptScore W1984587636C2777063308 @default.
- W1984587636 hasConceptScore W1984587636C2777506904 @default.
- W1984587636 hasConceptScore W1984587636C2777600175 @default.
- W1984587636 hasConceptScore W1984587636C2778119113 @default.
- W1984587636 hasConceptScore W1984587636C2778822529 @default.
- W1984587636 hasConceptScore W1984587636C2780580376 @default.
- W1984587636 hasConceptScore W1984587636C2780852908 @default.
- W1984587636 hasConceptScore W1984587636C2781413609 @default.
- W1984587636 hasConceptScore W1984587636C29730261 @default.
- W1984587636 hasConceptScore W1984587636C71924100 @default.
- W1984587636 hasConceptScore W1984587636C90924648 @default.
- W1984587636 hasLocation W19845876361 @default.
- W1984587636 hasLocation W19845876362 @default.
- W1984587636 hasOpenAccess W1984587636 @default.
- W1984587636 hasPrimaryLocation W19845876361 @default.
- W1984587636 hasRelatedWork W2018217408 @default.
- W1984587636 hasRelatedWork W2356732686 @default.
- W1984587636 hasRelatedWork W2362108816 @default.
- W1984587636 hasRelatedWork W2371533114 @default.
- W1984587636 hasRelatedWork W2373159162 @default.
- W1984587636 hasRelatedWork W2373562392 @default.
- W1984587636 hasRelatedWork W2381866845 @default.
- W1984587636 hasRelatedWork W2383619798 @default.
- W1984587636 hasRelatedWork W2389233550 @default.
- W1984587636 hasRelatedWork W2419503459 @default.
- W1984587636 isParatext "false" @default.
- W1984587636 isRetracted "false" @default.
- W1984587636 magId "1984587636" @default.
- W1984587636 workType "article" @default.