FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1984598304> ?p ?o ?g. }

• W1984598304 endingPage "83" @default.
• W1984598304 startingPage "57" @default.
• W1984598304 abstract "Cerebrospinal fluid (CSF)-contacting neurons form a part of the circumventricular organs of the central nervous system. Represented by different cytologic types and located in different regions, they constitute a CSF-contacting neuronal system, the most central periventricular ring of neurons in the brain organized concentrically according to our concept. Because the central nervous system of deuterostomian echinoderm starfishes and the prochordate lancelet is composed mainly of CSF-contacting-like neurons, we hypothesize that this cell type represents ancient cells, or protoneurons, in the vertebrate brain. Neurons may contact the ventricular CSF via their dendrites, axons, or perikarya. Most of the CSF-contacting nerve cells send their dendritic processes into the ventricular cavity, where they form ciliated terminals. These ciliated endings resemble those of known sensory cells. By means of axons, the CSF-contacting neurons also may contact the external CSF space, where the axons form terminals of neurohormonal type similar to those known in the neurohemal areas. The most simple CSF-contacting neurons of vertebrates are present in the terminal filum, spinal cord, and oblongate medulla. The dendritic pole of these medullospinal CSF-contacting neurons terminates with an enlargement bearing many stereocilia in the central canal. These cells are also supplied with a 9 x 2 + 2 kinocilium that may contact Reissner's fiber, the condensed secretory material of the subcommissural organ. The Reissner's fiber floating freely in the CSF leaves the central canal at the caudal open end of the terminal filum in lower vertebrates, and open communication is thus established between internal CSF and the surrounding tissue spaces. Resembling mechanoreceptors cytologically, the spinal CSF-contacting neurons send their axons to the outer surface of the spinal cord to form neurosecretory-type terminals. They also send collaterals to local neurons and to higher spinal segments. In the hypothalamic part of the diencephalon, neurons of two circumventricular organs, the paraventricular organ and the vascular sac, of the magnocellular neurosecretory nuclei and several parvocellular nuclei, form CSF-contacting dendritic terminals. A CSF-contacting neuronal area also was found in the telencephalon. The CSF-contacting dendrites of all these areas bear solitary 9 x 2 + 0 cilia and resemble chemoreceptors and developing photoreceptors cytologically. In electrophysiological experiments, the neurons of the paraventricular organ are highly sensitive to the composition of the ventricular CSF. The axons of the CSF-contacting neurons of the paraventricular organ and hypothalamic nuclei terminate in hypothalamic synaptic zones, and those of magno- and parvocellular neurosecretory nuclei also form neurohormonal terminals in the median eminence and neurohypophysis. The axons of the CSF-contacting neurons of the vascular sac run in the nervus and tractus sacci vasculosi to the nucleus (ganglion) sacci vasculosi. Some hypothalamic CSF-contacting neurons contain immunoreactive opsin and are candidates to represent the deep encephalic photoreceptors. In the newt, cells derived from the subependymal layer develop photoreceptor outer segments protruding to the lumen of the infundibular lobe under experimental conditions. Retinal and pineal photoreceptors and some of their secondary neurons possess common cytologic features with CSF-contacting neurons. They contact the retinal photoreceptor space and pineal recess, respectively, both cavities being derived from the third ventricle. In addition to ciliated dendritic terminals, there are intraventricular axons and neuronal perikarya contacting the CSF. Part of the CSF-contacting axons are serotoninergic; their perikarya are situated in the raphe nuclei. Intraventricular axons innervate the CSF-contacting dendrites, intraventricular nerve cells, and/or the ventricular surface of the ependyma. (ABSTRACT TRUNCATED)" @default.
• W1984598304 created "2016-06-24" @default.
• W1984598304 creator A5052991064 @default.
• W1984598304 creator A5087140122 @default.
• W1984598304 date "1998-04-01" @default.
• W1984598304 modified "2023-09-29" @default.
• W1984598304 title "Actual problems of the cerebrospinal fluid-contacting neurons" @default.
• W1984598304 cites W114647432 @default.
• W1984598304 cites W1213698419 @default.
• W1984598304 cites W139325378 @default.
• W1984598304 cites W1421424531 @default.
• W1984598304 cites W1481479394 @default.
• W1984598304 cites W1500028770 @default.
• W1984598304 cites W1512080627 @default.
• W1984598304 cites W1561141465 @default.
• W1984598304 cites W1575745275 @default.
• W1984598304 cites W1593117315 @default.
• W1984598304 cites W1604019759 @default.
• W1984598304 cites W172453099 @default.
• W1984598304 cites W17382146 @default.
• W1984598304 cites W1826093168 @default.
• W1984598304 cites W1964273161 @default.
• W1984598304 cites W1966025228 @default.
• W1984598304 cites W1966519754 @default.
• W1984598304 cites W1966606283 @default.
• W1984598304 cites W1966920066 @default.
• W1984598304 cites W1968163949 @default.
• W1984598304 cites W1969419996 @default.
• W1984598304 cites W1969487247 @default.
• W1984598304 cites W1970373750 @default.
• W1984598304 cites W1971297577 @default.
• W1984598304 cites W1972532165 @default.
• W1984598304 cites W1972669673 @default.
• W1984598304 cites W1974178194 @default.
• W1984598304 cites W1974318054 @default.
• W1984598304 cites W1975576335 @default.
• W1984598304 cites W1977766566 @default.
• W1984598304 cites W1978459241 @default.
• W1984598304 cites W1978858173 @default.
• W1984598304 cites W1978942802 @default.
• W1984598304 cites W1979635204 @default.
• W1984598304 cites W1980041772 @default.
• W1984598304 cites W1980833645 @default.
• W1984598304 cites W1982511107 @default.
• W1984598304 cites W1984236880 @default.
• W1984598304 cites W1987493556 @default.
• W1984598304 cites W1987654762 @default.
• W1984598304 cites W1988037169 @default.
• W1984598304 cites W1992150998 @default.
• W1984598304 cites W1992288642 @default.
• W1984598304 cites W1994082473 @default.
• W1984598304 cites W1995314274 @default.
• W1984598304 cites W1996024593 @default.
• W1984598304 cites W1997124473 @default.
• W1984598304 cites W1997209533 @default.
• W1984598304 cites W1999501162 @default.
• W1984598304 cites W2000540649 @default.
• W1984598304 cites W2001121223 @default.
• W1984598304 cites W2001211253 @default.
• W1984598304 cites W2002099091 @default.
• W1984598304 cites W2002318627 @default.
• W1984598304 cites W2002449610 @default.
• W1984598304 cites W2003882681 @default.
• W1984598304 cites W2004175693 @default.
• W1984598304 cites W2005022852 @default.
• W1984598304 cites W2008119895 @default.
• W1984598304 cites W2008224176 @default.
• W1984598304 cites W2008691722 @default.
• W1984598304 cites W2010018116 @default.
• W1984598304 cites W2011872161 @default.
• W1984598304 cites W2012567893 @default.
• W1984598304 cites W2013005522 @default.
• W1984598304 cites W2013796237 @default.
• W1984598304 cites W2014611378 @default.
• W1984598304 cites W2016305959 @default.
• W1984598304 cites W2017113345 @default.
• W1984598304 cites W2018394568 @default.
• W1984598304 cites W2018445261 @default.
• W1984598304 cites W2019624204 @default.
• W1984598304 cites W2019638314 @default.
• W1984598304 cites W2020113571 @default.
• W1984598304 cites W2020119067 @default.
• W1984598304 cites W2020374547 @default.
• W1984598304 cites W2021289680 @default.
• W1984598304 cites W2021928728 @default.
• W1984598304 cites W2022066650 @default.
• W1984598304 cites W2024909964 @default.
• W1984598304 cites W2025409047 @default.
• W1984598304 cites W2025636987 @default.
• W1984598304 cites W2025836006 @default.
• W1984598304 cites W2027189725 @default.
• W1984598304 cites W2027407548 @default.
• W1984598304 cites W2028786581 @default.
• W1984598304 cites W2029147339 @default.
• W1984598304 cites W2030178859 @default.
• W1984598304 cites W2031130823 @default.
• W1984598304 cites W2033942635 @default.
• W1984598304 cites W2034656750 @default.

• next