FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1984622817> ?p ?o ?g. }

• W1984622817 abstract "Stachybotrys chartarum (atra) is a toxic mold that grows on water-damaged cellulose-based materials. Research has revealed also that inhalation of S. chartarum spores caused marked changes in respiratory epithelium, especially to developing lungs. We analyzed the epigenetic potential of S. chartarum spore toxins on developing rat lung fibroblasts using single cell gel electrophoresis (comet assay). Isolated fetal lung fibroblasts were exposed to S. chartarum spore toxins for 15 min, 3, 14, or 24 hr and control cells were exposed to saline under the same conditions. Cells were embedded in agarose, electrophoresed under alkaline conditions and silver stained. DNA damage was assessed in terms of fragmentation as measured by comet tail length (DNA migration) and intensity (% DNA contained within head and tail). Upon visual inspection, control fibroblasts showed no DNA fragmentation whereas S. chartarum-treated cells had definable comets of various degrees depending upon the time-course. Analyses of the comets revealed that exposure to S. chartarum spore toxins for at least 15 min to 14 hr, induced increased DNA fragmentation in a time-dependent manner. The fact that exposure to toxins for 24 hr showed less damage suggested that developing lung fibroblasts may have the capability of repairing DNA fragmentation." @default.
• W1984622817 created "2016-06-24" @default.
• W1984622817 creator A5000086889 @default.
• W1984622817 creator A5000421313 @default.
• W1984622817 creator A5008217053 @default.
• W1984622817 creator A5050178516 @default.
• W1984622817 creator A5056189031 @default.
• W1984622817 creator A5065085602 @default.
• W1984622817 creator A5067912247 @default.
• W1984622817 date "2007-01-01" @default.
• W1984622817 modified "2023-10-17" @default.
• W1984622817 title "DNA fragmentation in developing lung fibroblasts exposed toStachybotrys chartarum (atra) toxins" @default.
• W1984622817 cites W1664410437 @default.
• W1984622817 cites W1969946488 @default.
• W1984622817 cites W1978904981 @default.
• W1984622817 cites W1985565746 @default.
• W1984622817 cites W1985939223 @default.
• W1984622817 cites W1993950524 @default.
• W1984622817 cites W2009041655 @default.
• W1984622817 cites W2026212555 @default.
• W1984622817 cites W2027651810 @default.
• W1984622817 cites W2031495829 @default.
• W1984622817 cites W2034485370 @default.
• W1984622817 cites W2065857667 @default.
• W1984622817 cites W2068536095 @default.
• W1984622817 cites W2082480414 @default.
• W1984622817 cites W2084708250 @default.
• W1984622817 cites W2091340154 @default.
• W1984622817 cites W2098040253 @default.
• W1984622817 cites W2107411016 @default.
• W1984622817 cites W2134279006 @default.
• W1984622817 cites W2141165846 @default.
• W1984622817 cites W2145205708 @default.
• W1984622817 cites W2149816576 @default.
• W1984622817 cites W2155907064 @default.
• W1984622817 cites W2157727603 @default.
• W1984622817 cites W2158700827 @default.
• W1984622817 cites W2162777232 @default.
• W1984622817 cites W2167897400 @default.
• W1984622817 cites W2168153001 @default.
• W1984622817 cites W2171879046 @default.
• W1984622817 cites W2254051985 @default.
• W1984622817 cites W2325838179 @default.
• W1984622817 cites W2422092175 @default.
• W1984622817 cites W2772781490 @default.
• W1984622817 cites W4232558975 @default.
• W1984622817 doi "https://doi.org/10.1002/ppul.20608" @default.
• W1984622817 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17534970" @default.
• W1984622817 hasPublicationYear "2007" @default.
• W1984622817 type Work @default.
• W1984622817 sameAs 1984622817 @default.
• W1984622817 citedByCount "6" @default.
• W1984622817 countsByYear W19846228172013 @default.
• W1984622817 countsByYear W19846228172014 @default.
• W1984622817 countsByYear W19846228172015 @default.
• W1984622817 crossrefType "journal-article" @default.
• W1984622817 hasAuthorship W1984622817A5000086889 @default.
• W1984622817 hasAuthorship W1984622817A5000421313 @default.
• W1984622817 hasAuthorship W1984622817A5008217053 @default.
• W1984622817 hasAuthorship W1984622817A5050178516 @default.
• W1984622817 hasAuthorship W1984622817A5056189031 @default.
• W1984622817 hasAuthorship W1984622817A5065085602 @default.
• W1984622817 hasAuthorship W1984622817A5067912247 @default.
• W1984622817 hasConcept C143425029 @default.
• W1984622817 hasConcept C153911025 @default.
• W1984622817 hasConcept C18903297 @default.
• W1984622817 hasConcept C190283241 @default.
• W1984622817 hasConcept C191015642 @default.
• W1984622817 hasConcept C2780358455 @default.
• W1984622817 hasConcept C31573885 @default.
• W1984622817 hasConcept C43759708 @default.
• W1984622817 hasConcept C552990157 @default.
• W1984622817 hasConcept C55493867 @default.
• W1984622817 hasConcept C86803240 @default.
• W1984622817 hasConcept C89423630 @default.
• W1984622817 hasConceptScore W1984622817C143425029 @default.
• W1984622817 hasConceptScore W1984622817C153911025 @default.
• W1984622817 hasConceptScore W1984622817C18903297 @default.
• W1984622817 hasConceptScore W1984622817C190283241 @default.
• W1984622817 hasConceptScore W1984622817C191015642 @default.
• W1984622817 hasConceptScore W1984622817C2780358455 @default.
• W1984622817 hasConceptScore W1984622817C31573885 @default.
• W1984622817 hasConceptScore W1984622817C43759708 @default.
• W1984622817 hasConceptScore W1984622817C552990157 @default.
• W1984622817 hasConceptScore W1984622817C55493867 @default.
• W1984622817 hasConceptScore W1984622817C86803240 @default.
• W1984622817 hasConceptScore W1984622817C89423630 @default.
• W1984622817 hasLocation W19846228171 @default.
• W1984622817 hasLocation W19846228172 @default.
• W1984622817 hasOpenAccess W1984622817 @default.
• W1984622817 hasPrimaryLocation W19846228171 @default.
• W1984622817 hasRelatedWork W1927227616 @default.
• W1984622817 hasRelatedWork W1980013772 @default.
• W1984622817 hasRelatedWork W1991247489 @default.
• W1984622817 hasRelatedWork W2006650971 @default.
• W1984622817 hasRelatedWork W2032337567 @default.
• W1984622817 hasRelatedWork W2042977727 @default.
• W1984622817 hasRelatedWork W2060104203 @default.
• W1984622817 hasRelatedWork W2126772104 @default.
• W1984622817 hasRelatedWork W2152333101 @default.

• next