FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1984642014> ?p ?o ?g. }

• W1984642014 endingPage "369" @default.
• W1984642014 startingPage "365" @default.
• W1984642014 abstract "Studies on carbonic anhydrase (CA, EC 4.2.1.1) inhibitors have increased due to several therapeutic applications while there are few investigations on activators. Here we investigated CA inhibitory and activatory capacities of a series of dopaminergic compounds on human carbonic anhydrase (hCA) isozymes I, II, and VI. 2-Amino-1,2,3,4-tetrahydronaphthalene-6,7-diol hydrobromide and 2-amino-1,2,3,4-tetrahydronaphthalene-5,6-diol hydrobromide were found to show effective inhibitory action on hCA I and II whereas 2-amino-5,6-dibromoindan hydrobromide and 2-amino-5-bromoindan hydrobromide exhibited only moderate inhibition against both isoforms, being more effective inhibitors of hCA VI. Ki values of the molecules 3–6 were in the range of 41.12–363 μM against hCA I, of 0.381–470 μM against hCA II and of 0.578–1.152 μM against hCA VI, respectively. Compound 7 behaved as a CA activator with KA values of 27.3 μM against hCA I, of 18.4 μM against hCA II and of 8.73 μM against hCA VI, respectively." @default.
• W1984642014 created "2016-06-24" @default.
• W1984642014 creator A5021780004 @default.
• W1984642014 creator A5035013697 @default.
• W1984642014 creator A5078313232 @default.
• W1984642014 creator A5087438602 @default.
• W1984642014 date "2011-06-23" @default.
• W1984642014 modified "2023-09-27" @default.
• W1984642014 title "Effects of dopaminergic compounds on carbonic anhydrase isozymes I, II, and VI" @default.
• W1984642014 cites W110069835 @default.
• W1984642014 cites W1513087030 @default.
• W1984642014 cites W1966933728 @default.
• W1984642014 cites W1969694148 @default.
• W1984642014 cites W1973061718 @default.
• W1984642014 cites W1982889315 @default.
• W1984642014 cites W1984074855 @default.
• W1984642014 cites W2001795074 @default.
• W1984642014 cites W2003128031 @default.
• W1984642014 cites W2005146437 @default.
• W1984642014 cites W2020138081 @default.
• W1984642014 cites W2020880561 @default.
• W1984642014 cites W2024130664 @default.
• W1984642014 cites W2025098818 @default.
• W1984642014 cites W2028475370 @default.
• W1984642014 cites W2030917579 @default.
• W1984642014 cites W2035873039 @default.
• W1984642014 cites W2042007637 @default.
• W1984642014 cites W2044844630 @default.
• W1984642014 cites W2047178318 @default.
• W1984642014 cites W2054838817 @default.
• W1984642014 cites W2054979333 @default.
• W1984642014 cites W2066095920 @default.
• W1984642014 cites W2068210639 @default.
• W1984642014 cites W2084330715 @default.
• W1984642014 cites W2100837269 @default.
• W1984642014 cites W2110095679 @default.
• W1984642014 cites W2146370713 @default.
• W1984642014 cites W2149861830 @default.
• W1984642014 cites W2158731470 @default.
• W1984642014 cites W2397681412 @default.
• W1984642014 cites W2920879323 @default.
• W1984642014 cites W4254279933 @default.
• W1984642014 cites W4293247451 @default.
• W1984642014 doi "https://doi.org/10.3109/14756366.2011.591290" @default.
• W1984642014 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21699374" @default.
• W1984642014 hasPublicationYear "2011" @default.
• W1984642014 type Work @default.
• W1984642014 sameAs 1984642014 @default.
• W1984642014 citedByCount "31" @default.
• W1984642014 countsByYear W19846420142012 @default.
• W1984642014 countsByYear W19846420142013 @default.
• W1984642014 countsByYear W19846420142014 @default.
• W1984642014 countsByYear W19846420142015 @default.
• W1984642014 countsByYear W19846420142016 @default.
• W1984642014 countsByYear W19846420142017 @default.
• W1984642014 countsByYear W19846420142020 @default.
• W1984642014 countsByYear W19846420142023 @default.
• W1984642014 crossrefType "journal-article" @default.
• W1984642014 hasAuthorship W1984642014A5021780004 @default.
• W1984642014 hasAuthorship W1984642014A5035013697 @default.
• W1984642014 hasAuthorship W1984642014A5078313232 @default.
• W1984642014 hasAuthorship W1984642014A5087438602 @default.
• W1984642014 hasConcept C119795356 @default.
• W1984642014 hasConcept C134018914 @default.
• W1984642014 hasConcept C137183658 @default.
• W1984642014 hasConcept C178790620 @default.
• W1984642014 hasConcept C181199279 @default.
• W1984642014 hasConcept C185592680 @default.
• W1984642014 hasConcept C2775914622 @default.
• W1984642014 hasConcept C2779176119 @default.
• W1984642014 hasConcept C513476851 @default.
• W1984642014 hasConcept C515207424 @default.
• W1984642014 hasConcept C55493867 @default.
• W1984642014 hasConcept C71240020 @default.
• W1984642014 hasConcept C86803240 @default.
• W1984642014 hasConceptScore W1984642014C119795356 @default.
• W1984642014 hasConceptScore W1984642014C134018914 @default.
• W1984642014 hasConceptScore W1984642014C137183658 @default.
• W1984642014 hasConceptScore W1984642014C178790620 @default.
• W1984642014 hasConceptScore W1984642014C181199279 @default.
• W1984642014 hasConceptScore W1984642014C185592680 @default.
• W1984642014 hasConceptScore W1984642014C2775914622 @default.
• W1984642014 hasConceptScore W1984642014C2779176119 @default.
• W1984642014 hasConceptScore W1984642014C513476851 @default.
• W1984642014 hasConceptScore W1984642014C515207424 @default.
• W1984642014 hasConceptScore W1984642014C55493867 @default.
• W1984642014 hasConceptScore W1984642014C71240020 @default.
• W1984642014 hasConceptScore W1984642014C86803240 @default.
• W1984642014 hasIssue "3" @default.
• W1984642014 hasLocation W19846420141 @default.
• W1984642014 hasLocation W19846420142 @default.
• W1984642014 hasOpenAccess W1984642014 @default.
• W1984642014 hasPrimaryLocation W19846420141 @default.
• W1984642014 hasRelatedWork W1548300662 @default.
• W1984642014 hasRelatedWork W1976629605 @default.
• W1984642014 hasRelatedWork W1984642014 @default.
• W1984642014 hasRelatedWork W2000584792 @default.
• W1984642014 hasRelatedWork W2030627791 @default.

• next