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Matches in SemOpenAlex for { <https://semopenalex.org/work/W1984659158> ?p ?o ?g. }

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• W1984659158 abstract "T-box (TBX) transcription factors are an ancient gene family with critical roles in embryogenesis. Currently, TBX3, TBX5, and TBX20 are TBX genes defined to have multiple protein isoforms created by alternative splicing and characterized by expression and functional studies. These proteins are important for development as mutations lead to severe developmental disorders in humans and mice. Cumulative studies suggest that alternative splicing of these genes can regulate TBX activities during multiple biological processes including cardiogenesis, limb development, and cancer mechanisms. This mini-review focuses on how alternative splicing adds complexity to transcriptional regulation of target genes controlled by TBX transcription factors." @default.
• W1984659158 created "2016-06-24" @default.
• W1984659158 creator A5055223897 @default.
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• W1984659158 date "2011-09-01" @default.
• W1984659158 modified "2023-09-24" @default.
• W1984659158 title "Alternative splicing of T-box transcription factor genes" @default.
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• W1984659158 doi "https://doi.org/10.1016/j.bbrc.2011.08.010" @default.
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