Matches in SemOpenAlex for { <https://semopenalex.org/work/W1984719822> ?p ?o ?g. }
- W1984719822 endingPage "30" @default.
- W1984719822 startingPage "27" @default.
- W1984719822 abstract "Nineteen intracranial germ cell tumours treated during the past 11 years were evaluated retrospectively. The tumours were classified into three groups according to the level of alpha-fetoprotein (AFP) and beta-human chorionic gonadotropin (HCG) in serum and cerebrospinal fluid, and the optimal treatment for each group was determined. Group A consisted of patients with normal titres of AFP and HCG, group B of patients with relatively high titres (< 10 times normal), and group C comprised patients with higher titres ( 10 times normal levels). In group A, an appropriate field and dose of irradiation was necessary to prevent craniospinal dissemination. In group B, none of four patients who underwent total or subtotal resection of the tumour had craniospinal disseminatio n or tumour recurrence, whereas dissemination occurred in four further patients, including two who had received radiochemotherapy only, and two who had undergone partial resection of the tumour. While patients in group C had dissemination at the time of initial diagnosis, most patients in group B developed dissemination more than 10 months after initial treatment, suggesting that the type of treatment received as first line therapy is important in patients in this group. The prognosis of patients in group C, however, was unaffected by the priority given to either surgery, radiation or chemotherapy as first line treatment. Craniospinal dissemination can be prevented in patients with germ cell tumours who have a relative increase in levels of AFP and HCG by aggressive removal of the tumours as first line therapy, regardless of the type of adjuvant therapy given." @default.
- W1984719822 created "2016-06-24" @default.
- W1984719822 creator A5000597691 @default.
- W1984719822 creator A5012156810 @default.
- W1984719822 creator A5022076444 @default.
- W1984719822 creator A5026713406 @default.
- W1984719822 creator A5029090311 @default.
- W1984719822 creator A5032894475 @default.
- W1984719822 creator A5033584393 @default.
- W1984719822 creator A5037426292 @default.
- W1984719822 creator A5051931392 @default.
- W1984719822 creator A5069240767 @default.
- W1984719822 date "2001-01-01" @default.
- W1984719822 modified "2023-10-05" @default.
- W1984719822 title "Detection of craniospinal dissemination of intracranial germ cell tumours based on serum and cerebrospinal fluid levels of tumour markers" @default.
- W1984719822 cites W1995958749 @default.
- W1984719822 cites W1999203811 @default.
- W1984719822 cites W2012894590 @default.
- W1984719822 cites W2023607392 @default.
- W1984719822 cites W2032085849 @default.
- W1984719822 cites W2036011016 @default.
- W1984719822 cites W2040404147 @default.
- W1984719822 cites W2043536578 @default.
- W1984719822 cites W2052842541 @default.
- W1984719822 cites W2091257502 @default.
- W1984719822 cites W4242877629 @default.
- W1984719822 cites W4250112510 @default.
- W1984719822 doi "https://doi.org/10.1054/jocn.2000.0750" @default.
- W1984719822 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11322122" @default.
- W1984719822 hasPublicationYear "2001" @default.
- W1984719822 type Work @default.
- W1984719822 sameAs 1984719822 @default.
- W1984719822 citedByCount "26" @default.
- W1984719822 countsByYear W19847198222012 @default.
- W1984719822 countsByYear W19847198222014 @default.
- W1984719822 countsByYear W19847198222016 @default.
- W1984719822 countsByYear W19847198222017 @default.
- W1984719822 countsByYear W19847198222019 @default.
- W1984719822 countsByYear W19847198222020 @default.
- W1984719822 countsByYear W19847198222021 @default.
- W1984719822 countsByYear W19847198222022 @default.
- W1984719822 countsByYear W19847198222023 @default.
- W1984719822 crossrefType "journal-article" @default.
- W1984719822 hasAuthorship W1984719822A5000597691 @default.
- W1984719822 hasAuthorship W1984719822A5012156810 @default.
- W1984719822 hasAuthorship W1984719822A5022076444 @default.
- W1984719822 hasAuthorship W1984719822A5026713406 @default.
- W1984719822 hasAuthorship W1984719822A5029090311 @default.
- W1984719822 hasAuthorship W1984719822A5032894475 @default.
- W1984719822 hasAuthorship W1984719822A5033584393 @default.
- W1984719822 hasAuthorship W1984719822A5037426292 @default.
- W1984719822 hasAuthorship W1984719822A5051931392 @default.
- W1984719822 hasAuthorship W1984719822A5069240767 @default.
- W1984719822 hasConcept C126322002 @default.
- W1984719822 hasConcept C141071460 @default.
- W1984719822 hasConcept C2775948956 @default.
- W1984719822 hasConcept C2776694085 @default.
- W1984719822 hasConcept C2776938808 @default.
- W1984719822 hasConcept C2777785397 @default.
- W1984719822 hasConcept C2777863537 @default.
- W1984719822 hasConcept C2778895204 @default.
- W1984719822 hasConcept C2779651940 @default.
- W1984719822 hasConcept C2780678043 @default.
- W1984719822 hasConcept C509974204 @default.
- W1984719822 hasConcept C71315377 @default.
- W1984719822 hasConcept C71924100 @default.
- W1984719822 hasConcept C90924648 @default.
- W1984719822 hasConceptScore W1984719822C126322002 @default.
- W1984719822 hasConceptScore W1984719822C141071460 @default.
- W1984719822 hasConceptScore W1984719822C2775948956 @default.
- W1984719822 hasConceptScore W1984719822C2776694085 @default.
- W1984719822 hasConceptScore W1984719822C2776938808 @default.
- W1984719822 hasConceptScore W1984719822C2777785397 @default.
- W1984719822 hasConceptScore W1984719822C2777863537 @default.
- W1984719822 hasConceptScore W1984719822C2778895204 @default.
- W1984719822 hasConceptScore W1984719822C2779651940 @default.
- W1984719822 hasConceptScore W1984719822C2780678043 @default.
- W1984719822 hasConceptScore W1984719822C509974204 @default.
- W1984719822 hasConceptScore W1984719822C71315377 @default.
- W1984719822 hasConceptScore W1984719822C71924100 @default.
- W1984719822 hasConceptScore W1984719822C90924648 @default.
- W1984719822 hasIssue "1" @default.
- W1984719822 hasLocation W19847198221 @default.
- W1984719822 hasLocation W19847198222 @default.
- W1984719822 hasOpenAccess W1984719822 @default.
- W1984719822 hasPrimaryLocation W19847198221 @default.
- W1984719822 hasRelatedWork W1557458308 @default.
- W1984719822 hasRelatedWork W1984719822 @default.
- W1984719822 hasRelatedWork W2038451303 @default.
- W1984719822 hasRelatedWork W2057372538 @default.
- W1984719822 hasRelatedWork W2077257271 @default.
- W1984719822 hasRelatedWork W2152396131 @default.
- W1984719822 hasRelatedWork W2355510565 @default.
- W1984719822 hasRelatedWork W2370865836 @default.
- W1984719822 hasRelatedWork W2384654496 @default.
- W1984719822 hasRelatedWork W2412908548 @default.
- W1984719822 hasVolume "8" @default.
- W1984719822 isParatext "false" @default.