FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1984773221> ?p ?o ?g. }

• W1984773221 endingPage "541" @default.
• W1984773221 startingPage "532" @default.
• W1984773221 abstract "Abstract Novel graft copolymers of 2-(dimethylamino)ethyl methacrylate (DMAEMA) with N-vinylpyrrolidone (NVP) were designed and synthesized by the free radical copolymerization of DMAEMA with precursor polymers of vinyl-functionalized poly(N-vinylpyrrolidone) (PVP). The ability of the PVP- grafted copolymers to bind and condense DNA was confirmed by ethidium bromide displacement assay, agarose gel electrophoresis and transmission electron microscopy. The presence of PVP in the copolymers had a favorable effect on the biophysical properties of polymer/DNA complexes. Colloidal stable complexes obtained from the copolymer systems, were shown to be separate, uniformly spherical nanoparticles by transmission electron microscopy. The approximate diameter of the complexes was 150–200 nm, as determined by dynamic light scattering studies. These results confirm an important role played by the PVP grafts in producing compact stable DNA complexes. The ζ-potential measurements revealed that the incorporation of the PVP grafts reduced the positive surface charge of polymer/DNA complexes. The cytotoxicity of the copolymers decreased with an increasing fraction of PVP. Furthermore, in vitro transfection experiments with these copolymers showed improved ability of transfection in cell culture, demonstrating an important role for PVP grafts in enhancement of the transfection efficiency." @default.
• W1984773221 created "2016-06-24" @default.
• W1984773221 creator A5008768921 @default.
• W1984773221 creator A5013289078 @default.
• W1984773221 creator A5031130649 @default.
• W1984773221 creator A5034969032 @default.
• W1984773221 date "2009-09-01" @default.
• W1984773221 modified "2023-09-26" @default.
• W1984773221 title "Polycationic graft copolymers of poly(N-vinylpyrrolidone) as non-viral vectors for gene transfection" @default.
• W1984773221 cites W1560355462 @default.
• W1984773221 cites W1970025394 @default.
• W1984773221 cites W1970029768 @default.
• W1984773221 cites W1972804296 @default.
• W1984773221 cites W1980352139 @default.
• W1984773221 cites W2007818475 @default.
• W1984773221 cites W2010228315 @default.
• W1984773221 cites W2026085888 @default.
• W1984773221 cites W2028322263 @default.
• W1984773221 cites W2038974287 @default.
• W1984773221 cites W2045528250 @default.
• W1984773221 cites W2046833821 @default.
• W1984773221 cites W2047292103 @default.
• W1984773221 cites W2058968181 @default.
• W1984773221 cites W2061573880 @default.
• W1984773221 cites W2070836823 @default.
• W1984773221 cites W2073325595 @default.
• W1984773221 cites W2073655835 @default.
• W1984773221 cites W2076585845 @default.
• W1984773221 cites W2078447684 @default.
• W1984773221 cites W2085672085 @default.
• W1984773221 cites W2086731246 @default.
• W1984773221 cites W2087004282 @default.
• W1984773221 cites W2142987628 @default.
• W1984773221 cites W2145017051 @default.
• W1984773221 cites W2163371839 @default.
• W1984773221 cites W4248724519 @default.
• W1984773221 cites W44906825 @default.
• W1984773221 doi "https://doi.org/10.2478/s11532-009-0045-8" @default.
• W1984773221 hasPublicationYear "2009" @default.
• W1984773221 type Work @default.
• W1984773221 sameAs 1984773221 @default.
• W1984773221 citedByCount "3" @default.
• W1984773221 countsByYear W19847732212021 @default.
• W1984773221 crossrefType "journal-article" @default.
• W1984773221 hasAuthorship W1984773221A5008768921 @default.
• W1984773221 hasAuthorship W1984773221A5013289078 @default.
• W1984773221 hasAuthorship W1984773221A5031130649 @default.
• W1984773221 hasAuthorship W1984773221A5034969032 @default.
• W1984773221 hasBestOaLocation W19847732211 @default.
• W1984773221 hasConcept C104317684 @default.
• W1984773221 hasConcept C132050475 @default.
• W1984773221 hasConcept C135983454 @default.
• W1984773221 hasConcept C146088050 @default.
• W1984773221 hasConcept C14631669 @default.
• W1984773221 hasConcept C155672457 @default.
• W1984773221 hasConcept C15920480 @default.
• W1984773221 hasConcept C171250308 @default.
• W1984773221 hasConcept C178790620 @default.
• W1984773221 hasConcept C185592680 @default.
• W1984773221 hasConcept C188027245 @default.
• W1984773221 hasConcept C192562407 @default.
• W1984773221 hasConcept C2776907736 @default.
• W1984773221 hasConcept C2778271344 @default.
• W1984773221 hasConcept C2778476535 @default.
• W1984773221 hasConcept C2779045410 @default.
• W1984773221 hasConcept C521977710 @default.
• W1984773221 hasConcept C54009773 @default.
• W1984773221 hasConcept C552990157 @default.
• W1984773221 hasConcept C55493867 @default.
• W1984773221 hasConceptScore W1984773221C104317684 @default.
• W1984773221 hasConceptScore W1984773221C132050475 @default.
• W1984773221 hasConceptScore W1984773221C135983454 @default.
• W1984773221 hasConceptScore W1984773221C146088050 @default.
• W1984773221 hasConceptScore W1984773221C14631669 @default.
• W1984773221 hasConceptScore W1984773221C155672457 @default.
• W1984773221 hasConceptScore W1984773221C15920480 @default.
• W1984773221 hasConceptScore W1984773221C171250308 @default.
• W1984773221 hasConceptScore W1984773221C178790620 @default.
• W1984773221 hasConceptScore W1984773221C185592680 @default.
• W1984773221 hasConceptScore W1984773221C188027245 @default.
• W1984773221 hasConceptScore W1984773221C192562407 @default.
• W1984773221 hasConceptScore W1984773221C2776907736 @default.
• W1984773221 hasConceptScore W1984773221C2778271344 @default.
• W1984773221 hasConceptScore W1984773221C2778476535 @default.
• W1984773221 hasConceptScore W1984773221C2779045410 @default.
• W1984773221 hasConceptScore W1984773221C521977710 @default.
• W1984773221 hasConceptScore W1984773221C54009773 @default.
• W1984773221 hasConceptScore W1984773221C552990157 @default.
• W1984773221 hasConceptScore W1984773221C55493867 @default.
• W1984773221 hasIssue "3" @default.
• W1984773221 hasLocation W19847732211 @default.
• W1984773221 hasLocation W19847732212 @default.
• W1984773221 hasOpenAccess W1984773221 @default.
• W1984773221 hasPrimaryLocation W19847732211 @default.
• W1984773221 hasRelatedWork W1533289191 @default.
• W1984773221 hasRelatedWork W1984773221 @default.
• W1984773221 hasRelatedWork W2018374514 @default.
• W1984773221 hasRelatedWork W2069888931 @default.

• next