FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1984793182> ?p ?o ?g. }

• W1984793182 endingPage "271" @default.
• W1984793182 startingPage "260" @default.
• W1984793182 abstract "When presented alone, H7 a and HY antigens elicit CD8 T-cell responses of similar amplitude, but H7 a totally abrogates the response to HY when both antigens are presented on the same antigen-presenting cell. We found that H7a- and HY-specific T-cell precursors had similar frequencies in nonimmune mice and expressed similar levels of CD5. The H7a -specific CD8 T-cell repertoire harvested at the time of primary response showed highly restricted T-cell receptor (TCR) diversity. Furthermore, T cells specific for H7a and HY expressed equivalent levels of CD8 and TCR and displayed similar tetramer decay rates. The key difference was that anti-H7a T cells exhibited a much more rapid TCR:epitope on-rate than anti-HY T cells. Coupled with evidence that primed CD8 T cells limit the duration of antigen presentation by killing or inactivating antigen-presenting cells, our data support a novel and simple model for immunodomination: the main feature of T cells that exert immunodomination is that, compared with other T cells, they are functionally primed after a shorter duration of antigen presentation." @default.
• W1984793182 created "2016-06-24" @default.
• W1984793182 creator A5053448893 @default.
• W1984793182 creator A5061943966 @default.
• W1984793182 creator A5067113587 @default.
• W1984793182 date "2005-04-01" @default.
• W1984793182 modified "2023-09-26" @default.
• W1984793182 title "CD8 T-cell ability to exert immunodomination correlates with T-cell receptor: Epitope association rate" @default.
• W1984793182 cites W1488377901 @default.
• W1984793182 cites W1501288691 @default.
• W1984793182 cites W1531269451 @default.
• W1984793182 cites W1555174324 @default.
• W1984793182 cites W1562441478 @default.
• W1984793182 cites W1576093565 @default.
• W1984793182 cites W1579000294 @default.
• W1984793182 cites W1585450293 @default.
• W1984793182 cites W1607360892 @default.
• W1984793182 cites W1758878637 @default.
• W1984793182 cites W1859429438 @default.
• W1984793182 cites W1928846417 @default.
• W1984793182 cites W1957876511 @default.
• W1984793182 cites W1970252429 @default.
• W1984793182 cites W1972256347 @default.
• W1984793182 cites W1980754944 @default.
• W1984793182 cites W1981622655 @default.
• W1984793182 cites W1986408270 @default.
• W1984793182 cites W1989329945 @default.
• W1984793182 cites W1996483176 @default.
• W1984793182 cites W1997339751 @default.
• W1984793182 cites W2003020339 @default.
• W1984793182 cites W2012948249 @default.
• W1984793182 cites W2015776459 @default.
• W1984793182 cites W2016285781 @default.
• W1984793182 cites W2017085953 @default.
• W1984793182 cites W2018947464 @default.
• W1984793182 cites W2022306056 @default.
• W1984793182 cites W2033374207 @default.
• W1984793182 cites W2039848934 @default.
• W1984793182 cites W2045209342 @default.
• W1984793182 cites W2051539436 @default.
• W1984793182 cites W2058634008 @default.
• W1984793182 cites W2060354653 @default.
• W1984793182 cites W2061671118 @default.
• W1984793182 cites W2065635440 @default.
• W1984793182 cites W2069871829 @default.
• W1984793182 cites W2075525784 @default.
• W1984793182 cites W2078452702 @default.
• W1984793182 cites W2080067734 @default.
• W1984793182 cites W2082712562 @default.
• W1984793182 cites W2086021932 @default.
• W1984793182 cites W2089543767 @default.
• W1984793182 cites W2097398162 @default.
• W1984793182 cites W2098852858 @default.
• W1984793182 cites W2099648098 @default.
• W1984793182 cites W2103044428 @default.
• W1984793182 cites W2108909957 @default.
• W1984793182 cites W2110459643 @default.
• W1984793182 cites W2118803516 @default.
• W1984793182 cites W2120841466 @default.
• W1984793182 cites W2122013117 @default.
• W1984793182 cites W2123142564 @default.
• W1984793182 cites W2124106344 @default.
• W1984793182 cites W2125113772 @default.
• W1984793182 cites W2130207165 @default.
• W1984793182 cites W2146527206 @default.
• W1984793182 cites W2161910879 @default.
• W1984793182 cites W2167195856 @default.
• W1984793182 doi "https://doi.org/10.1016/j.bbmt.2004.12.334" @default.
• W1984793182 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15812391" @default.
• W1984793182 hasPublicationYear "2005" @default.
• W1984793182 type Work @default.
• W1984793182 sameAs 1984793182 @default.
• W1984793182 citedByCount "13" @default.
• W1984793182 countsByYear W19847931822013 @default.
• W1984793182 countsByYear W19847931822014 @default.
• W1984793182 crossrefType "journal-article" @default.
• W1984793182 hasAuthorship W1984793182A5053448893 @default.
• W1984793182 hasAuthorship W1984793182A5061943966 @default.
• W1984793182 hasAuthorship W1984793182A5067113587 @default.
• W1984793182 hasBestOaLocation W19847931821 @default.
• W1984793182 hasConcept C147483822 @default.
• W1984793182 hasConcept C153911025 @default.
• W1984793182 hasConcept C154317977 @default.
• W1984793182 hasConcept C167672396 @default.
• W1984793182 hasConcept C19317047 @default.
• W1984793182 hasConcept C195616568 @default.
• W1984793182 hasConcept C202751555 @default.
• W1984793182 hasConcept C203014093 @default.
• W1984793182 hasConcept C2776090121 @default.
• W1984793182 hasConcept C2992881475 @default.
• W1984793182 hasConcept C55493867 @default.
• W1984793182 hasConcept C67662055 @default.
• W1984793182 hasConcept C71924100 @default.
• W1984793182 hasConcept C86803240 @default.
• W1984793182 hasConcept C8891405 @default.
• W1984793182 hasConcept C95444343 @default.
• W1984793182 hasConceptScore W1984793182C147483822 @default.
• W1984793182 hasConceptScore W1984793182C153911025 @default.

• next