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- W1984834725 abstract "To study dietary intake and serum concentrations of isoflavones in order to provide relative validation of isoflavone intake estimates from the Scottish Collaborative Group – Food-Frequency Questionnaire (SCG-FFQ). Validation study. Southern Scotland. Dietary intake of isoflavones was estimated using the semiquantitative SCG-FFQ and rank correlation and Kappa statistics were used for the relative validation of intakes against serum isoflavone concentrations in 203 male participants who were population controls in a case–control study of diet and prostate cancer. The median intake of isoflavones (daidzein and genistein) was 1.0 mg/day (I-QR 0.6–1.8). The median serum concentration of genistein was 33.79 nmol/l (I-QR 14.12–64.93), nearly twice that of daidzein (18.00 nmol/l, I-QR 8.26–29.45). Equol was detected in 49% of subjects; in these subjects the median was 0.67 nmol/l (I-QR 0.34–1.51). Isoflavone intake was significantly correlated with serum concentrations of daidzein (ρ=0.24, P=0.001), genistein (ρ=0.26, P<0.001) and total isoflavonoids (sum of daidzein, genistein and equol) (ρ=0.27, P<0.001). Whereas values for weighted Kappa ranged from 0.16 (P=0.002) for daidzein and equol combined to 0.22 (P<0.001) for genistein. These results demonstrate the suitability of the SCG-FFQ to rank usual isoflavone intakes in older Scottish men, a population observed to have low consumption of soy foods." @default.
- W1984834725 created "2016-06-24" @default.
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- W1984834725 date "2005-10-05" @default.
- W1984834725 modified "2023-09-27" @default.
- W1984834725 title "Phyto-oestrogen intake in Scottish men: use of serum to validate a self-administered food-frequency questionnaire in older men" @default.
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- W1984834725 doi "https://doi.org/10.1038/sj.ejcn.1602277" @default.
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