Matches in SemOpenAlex for { <https://semopenalex.org/work/W1984887641> ?p ?o ?g. }
- W1984887641 endingPage "106" @default.
- W1984887641 startingPage "97" @default.
- W1984887641 abstract "The epidermal cells obtained by mild trypsinization of guinea pig skin were first labeled with [3H]palmitate. Interestingly, free ceramide was one of the major radioactive products. The radioactivity of ceramide was located exclusively in the N-acyl moiety and palmitate was incorporated as such, without detectable chain modification. Sphingomyelin and glucosylceramide were not significantly labeled in spite of the active synthesis of ceramide. In order to investigate the action of lipolytic enzymes, the labeled cells were chased in a tracer-free medium. Bovine serum albumin (or fetal calf serum) and ionophore A23187 markedly stimulated the deacylation of lipids. The effects of the two stimulators were, however, distinctly different from each other. Bovine serum albumin (or fetal calf serum) caused principally the deacylation of triacylglycerol and ceramide, with little effect on that of phospholipids. In contrast, the effect of the ionophore was confined to phospholipid deacylation. In the presence of the ionophore, phosphatidylcholine and phosphatidylethanolamine were degraded to a similar extent. Palmitate was cleaved from both C-l and C-2 positions of phosphatidylcholine. The results suggest that the lipolytic systems of the epidermal cells can respond to extracellular stimuli and that the action of triacylglycerol lipase and ceramidase is controlled differently from that of phospholipases." @default.
- W1984887641 created "2016-06-24" @default.
- W1984887641 creator A5020130294 @default.
- W1984887641 creator A5032743477 @default.
- W1984887641 creator A5071531810 @default.
- W1984887641 date "1983-08-01" @default.
- W1984887641 modified "2023-09-27" @default.
- W1984887641 title "Deacylation of ceramide, triacylglycerol and phospholipids in guinea PIG epidermal cells" @default.
- W1984887641 cites W1501329774 @default.
- W1984887641 cites W1527218301 @default.
- W1984887641 cites W1532082124 @default.
- W1984887641 cites W1549255782 @default.
- W1984887641 cites W1549364769 @default.
- W1984887641 cites W1555026145 @default.
- W1984887641 cites W1564681939 @default.
- W1984887641 cites W1576533381 @default.
- W1984887641 cites W1670481545 @default.
- W1984887641 cites W1872873041 @default.
- W1984887641 cites W1922312486 @default.
- W1984887641 cites W1949202479 @default.
- W1984887641 cites W1967741965 @default.
- W1984887641 cites W1979668191 @default.
- W1984887641 cites W1985221711 @default.
- W1984887641 cites W1987416502 @default.
- W1984887641 cites W1988035305 @default.
- W1984887641 cites W1989292582 @default.
- W1984887641 cites W1994005910 @default.
- W1984887641 cites W1994096971 @default.
- W1984887641 cites W1995023052 @default.
- W1984887641 cites W1998863599 @default.
- W1984887641 cites W2013920525 @default.
- W1984887641 cites W2031411469 @default.
- W1984887641 cites W2031577863 @default.
- W1984887641 cites W2042281471 @default.
- W1984887641 cites W2052669536 @default.
- W1984887641 cites W2068505103 @default.
- W1984887641 cites W2070917754 @default.
- W1984887641 cites W2074180298 @default.
- W1984887641 cites W2077275014 @default.
- W1984887641 cites W2080637379 @default.
- W1984887641 cites W2080719401 @default.
- W1984887641 cites W2087236557 @default.
- W1984887641 cites W2088377211 @default.
- W1984887641 cites W2095566441 @default.
- W1984887641 cites W2114634890 @default.
- W1984887641 cites W2132184473 @default.
- W1984887641 cites W2151967603 @default.
- W1984887641 cites W2272841491 @default.
- W1984887641 cites W2319750100 @default.
- W1984887641 cites W2324041255 @default.
- W1984887641 cites W2412742209 @default.
- W1984887641 cites W2460694730 @default.
- W1984887641 cites W2505001494 @default.
- W1984887641 cites W28414865 @default.
- W1984887641 cites W4302044204 @default.
- W1984887641 doi "https://doi.org/10.1016/0005-2760(83)90103-0" @default.
- W1984887641 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6882789" @default.
- W1984887641 hasPublicationYear "1983" @default.
- W1984887641 type Work @default.
- W1984887641 sameAs 1984887641 @default.
- W1984887641 citedByCount "13" @default.
- W1984887641 crossrefType "journal-article" @default.
- W1984887641 hasAuthorship W1984887641A5020130294 @default.
- W1984887641 hasAuthorship W1984887641A5032743477 @default.
- W1984887641 hasAuthorship W1984887641A5071531810 @default.
- W1984887641 hasConcept C185592680 @default.
- W1984887641 hasConcept C190283241 @default.
- W1984887641 hasConcept C2776330855 @default.
- W1984887641 hasConcept C2777851122 @default.
- W1984887641 hasConcept C2778163477 @default.
- W1984887641 hasConcept C2778918659 @default.
- W1984887641 hasConcept C2780610907 @default.
- W1984887641 hasConcept C2781170229 @default.
- W1984887641 hasConcept C41625074 @default.
- W1984887641 hasConcept C55493867 @default.
- W1984887641 hasConcept C61322309 @default.
- W1984887641 hasConcept C62478195 @default.
- W1984887641 hasConcept C86803240 @default.
- W1984887641 hasConcept C86807702 @default.
- W1984887641 hasConceptScore W1984887641C185592680 @default.
- W1984887641 hasConceptScore W1984887641C190283241 @default.
- W1984887641 hasConceptScore W1984887641C2776330855 @default.
- W1984887641 hasConceptScore W1984887641C2777851122 @default.
- W1984887641 hasConceptScore W1984887641C2778163477 @default.
- W1984887641 hasConceptScore W1984887641C2778918659 @default.
- W1984887641 hasConceptScore W1984887641C2780610907 @default.
- W1984887641 hasConceptScore W1984887641C2781170229 @default.
- W1984887641 hasConceptScore W1984887641C41625074 @default.
- W1984887641 hasConceptScore W1984887641C55493867 @default.
- W1984887641 hasConceptScore W1984887641C61322309 @default.
- W1984887641 hasConceptScore W1984887641C62478195 @default.
- W1984887641 hasConceptScore W1984887641C86803240 @default.
- W1984887641 hasConceptScore W1984887641C86807702 @default.
- W1984887641 hasIssue "1" @default.
- W1984887641 hasLocation W19848876411 @default.
- W1984887641 hasLocation W19848876412 @default.
- W1984887641 hasOpenAccess W1984887641 @default.
- W1984887641 hasPrimaryLocation W19848876411 @default.