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- W1984887711 abstract "Background: “Alerting response” (AR) presents as the term used to describe the difference between first readings and the subsequent blood pressure (BP) readings, when it is sufficiently large and decreasing. However, little literature exists describing its prevalence and related cardiovascular outcomes. Ultimately, an alerting response may alter the course of treatment for a patient if it is not recognized, leading to overdiagnosis and overtreatment of hypertension. Methods: One hundred sixty three subjects (58.3 ± 14.6 years; 53.9% female, taking 1 ± 0.5 antihypertensive medications) that performed ABPM (SpaceLabs 90207) were evaluated consecutively and retrospectively. AR was defined as the difference between BP took by the nurse immediately before ambulatory BP monitoring (ABPM) installation, and daytime systolic and/or diastolic BP during ABPM > 20 mmHg, and 10 mmHg respectively. According to the definition above, patients were divided in two groups, AR+ (AR present), and AR- (AR absent). Age, gender, anthropometric measurements, BP, medications, and cardiovascular comorbities were evaluated (Student's t test, Mann-Whitney's test, qui2 test, and Fisher's test where appropriate). Results: Ninety (55.2%) patients presented AR, while 73 (44.8%) did not. There were differences in gender (67.7% female in RA- vs. 36.9% AR-, p < 0.001); tobacco smoking (6.6% in RA+ vs. 19.1% in RA-, p = 0.01); office BP (165.6 ± 25.4 / 93.6 ± 13.5 mmHg in RA+ vs. 134.9 ± 22.9 / 78.6 ± 15 mmHg in RA-, p < 0.001). In total, patients presented 24.5% diabetes, 67.4% dyslipidemia, 15.3% kidney dysfunction (creatinine clearance < 90 ml/min), 16.5% left ventricular hypertrophy, 3.6% coronary artery bypass surgery or angioplasty, 7.3% stroke, 3% heart failure, and 7.9% hypertensive retinopathy. Between groups, there were no differences in anthropometric measurements, and cardiovascular comorbities prevalence. Conclusion: AR prevalence is markedly high in the population analyzed. Patients with AR were predominately female, with less prevalence of tobacco smoking, and with higher BP at office. There were no differences between groups regarding cardiovascular comorbities." @default.
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- W1984887711 date "2010-06-01" @default.
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- W1984887711 title "IS ALERTING RESPONSE RELATED TO CARDIOVASCULAR COMORBITIES?: PP.14.32" @default.
- W1984887711 doi "https://doi.org/10.1097/01.hjh.0000378958.69608.fd" @default.
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