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• W1984929138 abstract "To examine the joint effect of family history and BMI on diabetes.Cross-sectional study.A rural community in Saskatchewan, Canada.The analysis was based on data from 2081 adults, 18-79 years of age, who participated in the Humboldt Study conducted in 2003. Doctor-diagnosed diabetes and family history of diabetes of biological parents and siblings were self-reported. Body weight and height were objectively measured. The interaction of family history and BMI on diabetes was assessed on an additive scale.The prevalence of diabetes was 7.9 %, and BMI and history of diabetes were two important predictors. The adjusted prevalence ratios were 1.76 (95 % CI 1.37, 2.27) and 2.59 (95 % CI 2.05, 3.31) for those with a BMI of 25.0-29.9 kg/m2 and of at least 30 kg/m2, respectively, compared with a BMI of less than 25 kg/m2, and was 2.41 (95 % CI 2.08, 2.80) for those with a family history of diabetes v. those without. The data indicated an additive interaction of family history and BMI on diabetes.When exposed to both family history and overweight/obesity, individuals would have an increased risk that was greater than the sum of their single effects. Reduction of BMI would also reduce the risk of diabetes associated family history." @default.
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• W1984929138 date "2009-08-26" @default.
• W1984929138 modified "2023-10-15" @default.
• W1984929138 title "Synergy of BMI and family history on diabetes: the Humboldt Study" @default.
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• W1984929138 doi "https://doi.org/10.1017/s1368980009991285" @default.
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