FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1984935568> ?p ?o ?g. }

• W1984935568 endingPage "30" @default.
• W1984935568 startingPage "24" @default.
• W1984935568 abstract "Previous studies have shown loss of heterozygosity (LOH) at the BRCA1 and FHIT genes in sporadic primary breast cancer. The aim of this study was to evaluate concomitant LOH at the BRCA1 and FHIT genes in sporadic breast cancer and investigate its influence on patient survival. Loss of heterozygosity was determined using microsatellite markers. The analysis on the informative cases (n = 72) indicated LOH at both the BRCA1 and FHIT loci in 25 cases (35%), the absence of LOH at both loci in 23 cases (32%), and the presence of LOH at one of the loci in 24 cases (33%). The concomitant LOH was associated with poor prognostic factors, such as large tumors (P = 0.01), axillary nodal involvement (P < 0.01), histologic grade III (P < 0.01), vascular invasion (P = 0.01), and negative hormone receptor (P = 0.02). After a median follow-up period of 48 months, the concomitant LOH group had the shortest survival (P < 0.02 by log-rank test; P < 0.05 by Cox model; hazard ratio of 4.87), compared with patients without LOH. These data suggest that concomitant allelic losses of the BRCA1 and FHIT genes are associated with more aggressive breast tumors." @default.
• W1984935568 created "2016-06-24" @default.
• W1984935568 creator A5001655428 @default.
• W1984935568 creator A5031233759 @default.
• W1984935568 creator A5042866715 @default.
• W1984935568 creator A5043928567 @default.
• W1984935568 creator A5056590283 @default.
• W1984935568 creator A5069337935 @default.
• W1984935568 creator A5079681197 @default.
• W1984935568 date "2010-05-01" @default.
• W1984935568 modified "2023-10-16" @default.
• W1984935568 title "Concomitant loss of heterozygosity at the BRCA1 and FHIT genes as a prognostic factor in sporadic breast cancer" @default.
• W1984935568 cites W1603850660 @default.
• W1984935568 cites W1892496998 @default.
• W1984935568 cites W1980191680 @default.
• W1984935568 cites W1985437593 @default.
• W1984935568 cites W1991852492 @default.
• W1984935568 cites W2000437208 @default.
• W1984935568 cites W2010871781 @default.
• W1984935568 cites W2050376635 @default.
• W1984935568 cites W2051184323 @default.
• W1984935568 cites W2051311335 @default.
• W1984935568 cites W2061445402 @default.
• W1984935568 cites W2065903080 @default.
• W1984935568 cites W2067028981 @default.
• W1984935568 cites W2072142679 @default.
• W1984935568 cites W2072240984 @default.
• W1984935568 cites W2077858999 @default.
• W1984935568 cites W2085772010 @default.
• W1984935568 cites W2130900820 @default.
• W1984935568 cites W2132434084 @default.
• W1984935568 cites W2135953007 @default.
• W1984935568 cites W2136569432 @default.
• W1984935568 cites W2137449168 @default.
• W1984935568 cites W4320581625 @default.
• W1984935568 doi "https://doi.org/10.1016/j.cancergencyto.2010.01.019" @default.
• W1984935568 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20417865" @default.
• W1984935568 hasPublicationYear "2010" @default.
• W1984935568 type Work @default.
• W1984935568 sameAs 1984935568 @default.
• W1984935568 citedByCount "8" @default.
• W1984935568 countsByYear W19849355682012 @default.
• W1984935568 countsByYear W19849355682013 @default.
• W1984935568 countsByYear W19849355682019 @default.
• W1984935568 countsByYear W19849355682023 @default.
• W1984935568 crossrefType "journal-article" @default.
• W1984935568 hasAuthorship W1984935568A5001655428 @default.
• W1984935568 hasAuthorship W1984935568A5031233759 @default.
• W1984935568 hasAuthorship W1984935568A5042866715 @default.
• W1984935568 hasAuthorship W1984935568A5043928567 @default.
• W1984935568 hasAuthorship W1984935568A5056590283 @default.
• W1984935568 hasAuthorship W1984935568A5069337935 @default.
• W1984935568 hasAuthorship W1984935568A5079681197 @default.
• W1984935568 hasBestOaLocation W19849355681 @default.
• W1984935568 hasConcept C104317684 @default.
• W1984935568 hasConcept C121608353 @default.
• W1984935568 hasConcept C126322002 @default.
• W1984935568 hasConcept C143589142 @default.
• W1984935568 hasConcept C143998085 @default.
• W1984935568 hasConcept C180754005 @default.
• W1984935568 hasConcept C2778264664 @default.
• W1984935568 hasConcept C2779384505 @default.
• W1984935568 hasConcept C2780646079 @default.
• W1984935568 hasConcept C502942594 @default.
• W1984935568 hasConcept C50382708 @default.
• W1984935568 hasConcept C530470458 @default.
• W1984935568 hasConcept C54355233 @default.
• W1984935568 hasConcept C555283112 @default.
• W1984935568 hasConcept C71924100 @default.
• W1984935568 hasConcept C86803240 @default.
• W1984935568 hasConceptScore W1984935568C104317684 @default.
• W1984935568 hasConceptScore W1984935568C121608353 @default.
• W1984935568 hasConceptScore W1984935568C126322002 @default.
• W1984935568 hasConceptScore W1984935568C143589142 @default.
• W1984935568 hasConceptScore W1984935568C143998085 @default.
• W1984935568 hasConceptScore W1984935568C180754005 @default.
• W1984935568 hasConceptScore W1984935568C2778264664 @default.
• W1984935568 hasConceptScore W1984935568C2779384505 @default.
• W1984935568 hasConceptScore W1984935568C2780646079 @default.
• W1984935568 hasConceptScore W1984935568C502942594 @default.
• W1984935568 hasConceptScore W1984935568C50382708 @default.
• W1984935568 hasConceptScore W1984935568C530470458 @default.
• W1984935568 hasConceptScore W1984935568C54355233 @default.
• W1984935568 hasConceptScore W1984935568C555283112 @default.
• W1984935568 hasConceptScore W1984935568C71924100 @default.
• W1984935568 hasConceptScore W1984935568C86803240 @default.
• W1984935568 hasFunder F4320322025 @default.
• W1984935568 hasIssue "1" @default.
• W1984935568 hasLocation W19849355681 @default.
• W1984935568 hasLocation W19849355682 @default.
• W1984935568 hasOpenAccess W1984935568 @default.
• W1984935568 hasPrimaryLocation W19849355681 @default.
• W1984935568 hasRelatedWork W1519069135 @default.
• W1984935568 hasRelatedWork W2015069073 @default.
• W1984935568 hasRelatedWork W2110189793 @default.
• W1984935568 hasRelatedWork W2128941900 @default.
• W1984935568 hasRelatedWork W2341241519 @default.
• W1984935568 hasRelatedWork W2363298459 @default.

• next