Matches in SemOpenAlex for { <https://semopenalex.org/work/W1984938411> ?p ?o ?g. }
Showing items 1 to 84 of
84
with 100 items per page.
- W1984938411 endingPage "305" @default.
- W1984938411 startingPage "300" @default.
- W1984938411 abstract "The role of CFTR in lysosome acidification was examined in CFPAC-1 pancreatic adenocarcinoma cells with the delta F508 mutation that were transduced with a retroviral vector (PLJ-CFPAC) or with the normal CFTR gene (CFTR-CFPAC). Steady-state lysosomal pHi in intact cells was lower in PLJ-CFPAC cells than CFTR-CFPAC cells (3.55 vs 3.80) and was not affected by cAMP or forskolin. Initial rates of ATP-dependent acidification of isolated lysosomes and steady-state ATP-dependent pHi were similar in both cell lines over a range of chloride concentrations and were not altered when cells were exposed to cAMP or to forskolin prior to preparation of lysosomes. These observations suggest that CFTR plays no role in acidification of lysosomes, possibly due to limited permeability of lysosomal membranes to chloride." @default.
- W1984938411 created "2016-06-24" @default.
- W1984938411 creator A5005450363 @default.
- W1984938411 creator A5048399002 @default.
- W1984938411 creator A5051344823 @default.
- W1984938411 creator A5056655206 @default.
- W1984938411 date "1992-04-01" @default.
- W1984938411 modified "2023-09-26" @default.
- W1984938411 title "Role of CFTR in lysosome acidification" @default.
- W1984938411 cites W1480251615 @default.
- W1984938411 cites W1496287649 @default.
- W1984938411 cites W1599810052 @default.
- W1984938411 cites W1982071077 @default.
- W1984938411 cites W1995240556 @default.
- W1984938411 cites W2001680909 @default.
- W1984938411 cites W2046293048 @default.
- W1984938411 cites W2067936312 @default.
- W1984938411 cites W2074809541 @default.
- W1984938411 cites W2075390708 @default.
- W1984938411 cites W2100432609 @default.
- W1984938411 cites W2119048447 @default.
- W1984938411 cites W2231864270 @default.
- W1984938411 cites W39387605 @default.
- W1984938411 doi "https://doi.org/10.1016/0006-291x(92)91192-s" @default.
- W1984938411 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1373612" @default.
- W1984938411 hasPublicationYear "1992" @default.
- W1984938411 type Work @default.
- W1984938411 sameAs 1984938411 @default.
- W1984938411 citedByCount "18" @default.
- W1984938411 countsByYear W19849384112012 @default.
- W1984938411 countsByYear W19849384112015 @default.
- W1984938411 countsByYear W19849384112016 @default.
- W1984938411 countsByYear W19849384112021 @default.
- W1984938411 crossrefType "journal-article" @default.
- W1984938411 hasAuthorship W1984938411A5005450363 @default.
- W1984938411 hasAuthorship W1984938411A5048399002 @default.
- W1984938411 hasAuthorship W1984938411A5051344823 @default.
- W1984938411 hasAuthorship W1984938411A5056655206 @default.
- W1984938411 hasBestOaLocation W19849384112 @default.
- W1984938411 hasConcept C145822097 @default.
- W1984938411 hasConcept C181199279 @default.
- W1984938411 hasConcept C185592680 @default.
- W1984938411 hasConcept C202751555 @default.
- W1984938411 hasConcept C2779276759 @default.
- W1984938411 hasConcept C2780216420 @default.
- W1984938411 hasConcept C54355233 @default.
- W1984938411 hasConcept C55493867 @default.
- W1984938411 hasConcept C81885089 @default.
- W1984938411 hasConcept C86803240 @default.
- W1984938411 hasConcept C95444343 @default.
- W1984938411 hasConceptScore W1984938411C145822097 @default.
- W1984938411 hasConceptScore W1984938411C181199279 @default.
- W1984938411 hasConceptScore W1984938411C185592680 @default.
- W1984938411 hasConceptScore W1984938411C202751555 @default.
- W1984938411 hasConceptScore W1984938411C2779276759 @default.
- W1984938411 hasConceptScore W1984938411C2780216420 @default.
- W1984938411 hasConceptScore W1984938411C54355233 @default.
- W1984938411 hasConceptScore W1984938411C55493867 @default.
- W1984938411 hasConceptScore W1984938411C81885089 @default.
- W1984938411 hasConceptScore W1984938411C86803240 @default.
- W1984938411 hasConceptScore W1984938411C95444343 @default.
- W1984938411 hasIssue "1" @default.
- W1984938411 hasLocation W19849384111 @default.
- W1984938411 hasLocation W19849384112 @default.
- W1984938411 hasLocation W19849384113 @default.
- W1984938411 hasOpenAccess W1984938411 @default.
- W1984938411 hasPrimaryLocation W19849384111 @default.
- W1984938411 hasRelatedWork W1984938411 @default.
- W1984938411 hasRelatedWork W2010050523 @default.
- W1984938411 hasRelatedWork W2234636301 @default.
- W1984938411 hasRelatedWork W2464503524 @default.
- W1984938411 hasRelatedWork W2467933912 @default.
- W1984938411 hasRelatedWork W3099945785 @default.
- W1984938411 hasRelatedWork W4220919142 @default.
- W1984938411 hasRelatedWork W4235542315 @default.
- W1984938411 hasRelatedWork W4243314230 @default.
- W1984938411 hasRelatedWork W4283069787 @default.
- W1984938411 hasVolume "184" @default.
- W1984938411 isParatext "false" @default.
- W1984938411 isRetracted "false" @default.
- W1984938411 magId "1984938411" @default.
- W1984938411 workType "article" @default.