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• W1984966797 abstract "You have accessJournal of UrologyUrodynamics/Incontinence/Female Urology: Female Urology1 Apr 2015MP81-12 CLINICAL COURSE OF URINARY INCONTINENCE IN WOMEN WITH TYPE I DIABETES: LONGITUDINAL FINDINGS FROM DCCT/EDIC Sarah K. Holt, J. Quentin Clemens, James Hotaling, Alan M. Jacobsen, Barbara H. Braffett, Patricia A. Cleary, Hunter Wessells, Aruna V. Sarma, and DCCT/EDIC Research Group Sarah K. HoltSarah K. Holt More articles by this author , J. Quentin ClemensJ. Quentin Clemens More articles by this author , James HotalingJames Hotaling More articles by this author , Alan M. JacobsenAlan M. Jacobsen More articles by this author , Barbara H. BraffettBarbara H. Braffett More articles by this author , Patricia A. ClearyPatricia A. Cleary More articles by this author , Hunter WessellsHunter Wessells More articles by this author , Aruna V. SarmaAruna V. Sarma More articles by this author , and DCCT/EDIC Research Group More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2015.02.2890AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES Urinary incontinence (UI) in women is a dynamic condition with numerous factors contributing to its risk, progression and remission. Since most studies have focused on estimating prevalence of UI at a single time point, our understanding of its development and natural history is limited. The goal of this study is to describe the long-term time course of UI in women with type 1 diabetes (T1DM). METHODS Longitudinal data from 604 females in the Epidemiology of Diabetes Interventions and Complications (EDIC) study, an epidemiologic observation follow up of the Diabetes Control and Complications Trial (DCCT) cohort, defined UI annually over 7 years (EDIC years 13 through 19) as a “Yes” response to a single question querying presence of urinary incontinence. No UI was defined as “No” to the same annual question. Subjects were categorized into 4 groups: No UI, isolated UI for a single event of <=2 years duration, episodic UI for subjects flipping between UI and no UI at least twice over study period, and persistent UI for subjects never returning to a state of no symptoms. RESULTS Average age at EDIC year 13 in this study group was 46 years. Prevalence of UI increased from 18.1% (n=102) at EDIC year 13 to 32.4% (n=187) by EDIC year 19; 49% of women never reported UI during the 7 year follow up. Fifteen percent reported persistent UI, 14% reported isolated UI and 22% reported episodic UI. Likelihood of remission decreased with every additional year of prior reported UI, from 41% chance after first report of UI to only 15% for those with 4 consecutive years of UI (Figure 1). CONCLUSIONS UI is a dynamic state in women with T1DM that may be modifiable. Studies describing factors related to its clinical course are underway. Detailed documentation of the frequency and persistence of incontinence and its risk factors in women with T1DM could be critical information in prevention and treatment of urinary symptoms in women with diabetes. © 2015 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 193Issue 4SApril 2015Page: e1033 Advertisement Copyright & Permissions© 2015 by American Urological Association Education and Research, Inc.MetricsAuthor Information Sarah K. Holt More articles by this author J. Quentin Clemens More articles by this author James Hotaling More articles by this author Alan M. Jacobsen More articles by this author Barbara H. Braffett More articles by this author Patricia A. Cleary More articles by this author Hunter Wessells More articles by this author Aruna V. Sarma More articles by this author DCCT/EDIC Research Group More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ..." @default.
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• W1984966797 title "MP81-12 CLINICAL COURSE OF URINARY INCONTINENCE IN WOMEN WITH TYPE I DIABETES: LONGITUDINAL FINDINGS FROM DCCT/EDIC" @default.
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