FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1984990206> ?p ?o ?g. }

• W1984990206 endingPage "2860" @default.
• W1984990206 startingPage "2853" @default.
• W1984990206 abstract "This study aimed to investigate the relationship between skeletal muscle, fibre type composition, functional respiratory impairment and exercise tolerance in patients with moderate to severe chronic obstructive pulmonary disease (COPD). A group of 22 COPD patients and 10 healthy control subjects were studied. In COPD patients, vital capacity (VC) and forced expiratory volume in one second (FEV1) were reduced to 79% and 51%, respectively. Diffusion indices (transfer factor of the lung for carbon monoxide (TL,CO) and carbon monoxide transfer coefficient (KCO)) were also reduced. Arterial oxygen tension (Pa,O2) was normal or slightly altered. A maximal exercise test was performed and anaerobic threshold was calculated. Muscle samples from vastus lateralis were obtained by needle biopsy. Myosin heavy chain (MHC) and light chain (MLC) isoforms were separated by gel electrophoresis and quantified by densitometry. MHC isoforms were considered as molecular markers of fibre types. The proportion of the fast MHC-2B isoform was increased in COPD patients. TL,CO, KCO, VC and FEV1 were positively correlated with slow MHC isoform content. TL,CO and KCO were also negatively correlated with the content of the fast MHC-2B isoform. No correlation was found between exercise parameters and MHC isoform composition. The co-ordinated expression between MHC and MLC isoforms was altered in COPD patients. We conclude that reduced oxygen availability, probably in combination with muscle disuse, may determine muscle alterations in chronic obstructive pulmonary disease patients. The altered correlations between myosin heavy chain and light chain isoforms suggest that co-ordinated protein expression is lost in chronic obstructive pulmonary disease muscles." @default.
• W1984990206 created "2016-06-24" @default.
• W1984990206 creator A5006193222 @default.
• W1984990206 creator A5041657392 @default.
• W1984990206 creator A5047398121 @default.
• W1984990206 creator A5049645088 @default.
• W1984990206 creator A5052081233 @default.
• W1984990206 creator A5052575701 @default.
• W1984990206 creator A5054822034 @default.
• W1984990206 creator A5057408967 @default.
• W1984990206 date "1997-12-01" @default.
• W1984990206 modified "2023-09-25" @default.
• W1984990206 title "Fibre types in skeletal muscles of chronic obstructive pulmonary disease patients related to respiratory function and exercise tolerance" @default.
• W1984990206 cites W1559230807 @default.
• W1984990206 cites W1559546823 @default.
• W1984990206 cites W1862674076 @default.
• W1984990206 cites W1972499537 @default.
• W1984990206 cites W2011073380 @default.
• W1984990206 cites W2014888880 @default.
• W1984990206 cites W2018418341 @default.
• W1984990206 cites W2018893486 @default.
• W1984990206 cites W2019299494 @default.
• W1984990206 cites W2027047803 @default.
• W1984990206 cites W2043862418 @default.
• W1984990206 cites W2050663276 @default.
• W1984990206 cites W2057322951 @default.
• W1984990206 cites W2058425999 @default.
• W1984990206 cites W2070822542 @default.
• W1984990206 cites W2083173059 @default.
• W1984990206 cites W2087368326 @default.
• W1984990206 cites W2097870728 @default.
• W1984990206 cites W2135377155 @default.
• W1984990206 cites W2161424531 @default.
• W1984990206 cites W2162539094 @default.
• W1984990206 cites W2176715668 @default.
• W1984990206 doi "https://doi.org/10.1183/09031936.97.10122853" @default.
• W1984990206 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9493673" @default.
• W1984990206 hasPublicationYear "1997" @default.
• W1984990206 type Work @default.
• W1984990206 sameAs 1984990206 @default.
• W1984990206 citedByCount "151" @default.
• W1984990206 countsByYear W19849902062012 @default.
• W1984990206 countsByYear W19849902062013 @default.
• W1984990206 countsByYear W19849902062014 @default.
• W1984990206 countsByYear W19849902062015 @default.
• W1984990206 countsByYear W19849902062016 @default.
• W1984990206 countsByYear W19849902062017 @default.
• W1984990206 countsByYear W19849902062018 @default.
• W1984990206 countsByYear W19849902062020 @default.
• W1984990206 countsByYear W19849902062021 @default.
• W1984990206 countsByYear W19849902062022 @default.
• W1984990206 countsByYear W19849902062023 @default.
• W1984990206 crossrefType "journal-article" @default.
• W1984990206 hasAuthorship W1984990206A5006193222 @default.
• W1984990206 hasAuthorship W1984990206A5041657392 @default.
• W1984990206 hasAuthorship W1984990206A5047398121 @default.
• W1984990206 hasAuthorship W1984990206A5049645088 @default.
• W1984990206 hasAuthorship W1984990206A5052081233 @default.
• W1984990206 hasAuthorship W1984990206A5052575701 @default.
• W1984990206 hasAuthorship W1984990206A5054822034 @default.
• W1984990206 hasAuthorship W1984990206A5057408967 @default.
• W1984990206 hasBestOaLocation W19849902061 @default.
• W1984990206 hasConcept C104317684 @default.
• W1984990206 hasConcept C126322002 @default.
• W1984990206 hasConcept C134018914 @default.
• W1984990206 hasConcept C164705383 @default.
• W1984990206 hasConcept C185592680 @default.
• W1984990206 hasConcept C2776780178 @default.
• W1984990206 hasConcept C2779959927 @default.
• W1984990206 hasConcept C53345823 @default.
• W1984990206 hasConcept C55493867 @default.
• W1984990206 hasConcept C6997183 @default.
• W1984990206 hasConcept C71924100 @default.
• W1984990206 hasConceptScore W1984990206C104317684 @default.
• W1984990206 hasConceptScore W1984990206C126322002 @default.
• W1984990206 hasConceptScore W1984990206C134018914 @default.
• W1984990206 hasConceptScore W1984990206C164705383 @default.
• W1984990206 hasConceptScore W1984990206C185592680 @default.
• W1984990206 hasConceptScore W1984990206C2776780178 @default.
• W1984990206 hasConceptScore W1984990206C2779959927 @default.
• W1984990206 hasConceptScore W1984990206C53345823 @default.
• W1984990206 hasConceptScore W1984990206C55493867 @default.
• W1984990206 hasConceptScore W1984990206C6997183 @default.
• W1984990206 hasConceptScore W1984990206C71924100 @default.
• W1984990206 hasIssue "12" @default.
• W1984990206 hasLocation W19849902061 @default.
• W1984990206 hasLocation W19849902062 @default.
• W1984990206 hasOpenAccess W1984990206 @default.
• W1984990206 hasPrimaryLocation W19849902061 @default.
• W1984990206 hasRelatedWork W1974568996 @default.
• W1984990206 hasRelatedWork W2005941627 @default.
• W1984990206 hasRelatedWork W2016840789 @default.
• W1984990206 hasRelatedWork W2046993766 @default.
• W1984990206 hasRelatedWork W2081376013 @default.
• W1984990206 hasRelatedWork W2144576666 @default.
• W1984990206 hasRelatedWork W2309978229 @default.
• W1984990206 hasRelatedWork W2463478234 @default.
• W1984990206 hasRelatedWork W2748952813 @default.

• next