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- W1985005833 abstract "Five genetically defined strains of female rats were exposed to whole-body radiation with a single dose of 50 rad of fission neutrons. After 1 year 56% of the Long-Evans and Sprague-Dawely strains showed at least one mammary tumor; 25-29% of the Buffalo and Fischer-344 strains and only 5% of the Wistar-Lewis strain and palpable mammary tumors. Only one tumor was found among 73 unirradiated controls during the 1-year observation period. Approximately two-thirds of 50 mammary analyzed pathologically were adenofibromas and fibroadenomas; one-third were adenocarcinomas. The Kaplan-Meier method of life table analysis was used to deal with the problem of intercurrent mortality. A genetic factor seems evident in rat mammary tumorigenesis following exposure to fission neutrons." @default.
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- W1985005833 date "1982-02-01" @default.
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- W1985005833 title "Genetic Component in Rat Mammary Carcinogenesis" @default.
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- W1985005833 doi "https://doi.org/10.2307/3575772" @default.
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