Matches in SemOpenAlex for { <https://semopenalex.org/work/W1985012801> ?p ?o ?g. }
Showing items 1 to 72 of
72
with 100 items per page.
- W1985012801 abstract "The launch on the market of a new compound is always an important event for a specialty, particularly when the mechanism of action is completely new. It is the case with sugammadex, a cyclodextrin able to encapsulate specifically and only nondepolarizing steroidal muscles relaxant, rocuronium or vecuronium. The clinical trials which have been performed for sugammadex approval have demonstrated promising results. Sugammadex is able to rapidly reverse (2-5 min) different levels of neuromuscular blockade: moderate (e.g., T2 recovery), deep (e.g., PTC 1-2 recovery) and also few minutes (3-15) after rocuronium administration. Thus, the sugammadex's onset time is about 10 times more rapid than neostigmine without the need of concomitantly atropine administration. Sugammadex has only been tested in small sample size of patients. Therefore, the exact place in the anesthetic practice, the potential indications, the safety profile on a large-scale, thus remain to determine. In particular, how it will modify our current practices characterized to date by 1) under-use of neuromuscular monitoring, 2) a marginal practice of reversal and 3) a wide use of benzylisoquinolines : atracurium and cis-atracurium? Finally, what will be the medical strategies to justify an additional cost when compared to neostigmine?" @default.
- W1985012801 created "2016-06-24" @default.
- W1985012801 creator A5040485712 @default.
- W1985012801 date "2009-09-01" @default.
- W1985012801 modified "2023-09-26" @default.
- W1985012801 title "Le sugammadex : une nouveauté qui s’inscrit dans le cadre de l’amélioration de la sécurité des patients ou un simple gadget ?" @default.
- W1985012801 cites W1546921352 @default.
- W1985012801 cites W1965100574 @default.
- W1985012801 cites W1984151878 @default.
- W1985012801 cites W1989419447 @default.
- W1985012801 cites W1990230652 @default.
- W1985012801 cites W1999831583 @default.
- W1985012801 cites W2003269031 @default.
- W1985012801 cites W2003635400 @default.
- W1985012801 cites W2005754237 @default.
- W1985012801 cites W2011479504 @default.
- W1985012801 cites W2014283710 @default.
- W1985012801 cites W2017403704 @default.
- W1985012801 cites W2029399557 @default.
- W1985012801 cites W2038272248 @default.
- W1985012801 cites W2045419076 @default.
- W1985012801 cites W2060418932 @default.
- W1985012801 cites W2061871410 @default.
- W1985012801 cites W2064985822 @default.
- W1985012801 cites W2067216287 @default.
- W1985012801 cites W2071366551 @default.
- W1985012801 cites W2080240719 @default.
- W1985012801 cites W2083574661 @default.
- W1985012801 cites W2113994462 @default.
- W1985012801 cites W2114985742 @default.
- W1985012801 cites W2126523604 @default.
- W1985012801 cites W2139013122 @default.
- W1985012801 cites W2147773646 @default.
- W1985012801 cites W2152365807 @default.
- W1985012801 cites W2154734472 @default.
- W1985012801 cites W2154969144 @default.
- W1985012801 cites W2164261563 @default.
- W1985012801 cites W2526675427 @default.
- W1985012801 doi "https://doi.org/10.1016/s0750-7658(09)72490-6" @default.
- W1985012801 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19887280" @default.
- W1985012801 hasPublicationYear "2009" @default.
- W1985012801 type Work @default.
- W1985012801 sameAs 1985012801 @default.
- W1985012801 citedByCount "8" @default.
- W1985012801 countsByYear W19850128012014 @default.
- W1985012801 countsByYear W19850128012017 @default.
- W1985012801 crossrefType "journal-article" @default.
- W1985012801 hasAuthorship W1985012801A5040485712 @default.
- W1985012801 hasConcept C2776277131 @default.
- W1985012801 hasConcept C2776988050 @default.
- W1985012801 hasConcept C2777411258 @default.
- W1985012801 hasConcept C2778560516 @default.
- W1985012801 hasConcept C2909465803 @default.
- W1985012801 hasConcept C42219234 @default.
- W1985012801 hasConcept C71924100 @default.
- W1985012801 hasConceptScore W1985012801C2776277131 @default.
- W1985012801 hasConceptScore W1985012801C2776988050 @default.
- W1985012801 hasConceptScore W1985012801C2777411258 @default.
- W1985012801 hasConceptScore W1985012801C2778560516 @default.
- W1985012801 hasConceptScore W1985012801C2909465803 @default.
- W1985012801 hasConceptScore W1985012801C42219234 @default.
- W1985012801 hasConceptScore W1985012801C71924100 @default.
- W1985012801 hasLocation W19850128011 @default.
- W1985012801 hasLocation W19850128012 @default.
- W1985012801 hasOpenAccess W1985012801 @default.
- W1985012801 hasPrimaryLocation W19850128011 @default.
- W1985012801 hasRelatedWork W2011765774 @default.
- W1985012801 hasRelatedWork W2082385062 @default.
- W1985012801 isParatext "false" @default.
- W1985012801 isRetracted "false" @default.
- W1985012801 magId "1985012801" @default.
- W1985012801 workType "article" @default.