Matches in SemOpenAlex for { <https://semopenalex.org/work/W1985014765> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W1985014765 endingPage "180" @default.
- W1985014765 startingPage "173" @default.
- W1985014765 abstract "Amelogenin-mineral interactions were investigated using an in vitro binding approach. Rat incisor enamel matrix proteins (mainly amelogenins) were dissolved in synthetic enamel fluid and allowed to equilibrate with deproteinised developing enamel crystals. The results showed that amlogenin proteins of 21, 23, 24, 26 and 27-kDa (corresponding to nascent and partially degraded amelogenins) were associated with the crystals whilst the lower Mr amelogenins (<21KDa) remained free in the synthetic enamel fluid. These data suggest the nascent and partially degraded amelogenins may interact with developing enamel crystals and could influence their growth. Albumin-mineral interactions were investigated by extracting developing rat incisor enamel with synthetic enamel fluid. Insoluble material (including the enamel crystals) was then further extracted with 0.1 M phosphate buffer (pH 7.4) to desorb any mineral bound proteins. Western blotting using anti-albumin antibodies showed that almost all of the albumin from the secretory stage enamel and a significant proportion of the albumin present in early transition stage was extractable in the synthetic enamel fluid. However. synthetic enamel fluid did not extract albumin from late transition or maturation stage tissue, which could only be removed following further extraction with phosphate buffer. Albumin degradation was apparent during the transition and maturation stages, where it is degraded and ultimately removed. This binding pattern may be related to amelogenin degradation and removal during the transition stage,. permitting albumin access to the previously obscured crystal surfaces. That the secretory stage matrix appears to protect secretory stage crystals from albumin may be an important consideration in the aetiology of enamel hypoplasias (i.e. incomplete crystal growth) and when using dissociative extraction procedures for the identification of mineral bound proteins." @default.
- W1985014765 created "2016-06-24" @default.
- W1985014765 creator A5007086297 @default.
- W1985014765 creator A5012208618 @default.
- W1985014765 creator A5034470368 @default.
- W1985014765 creator A5062033888 @default.
- W1985014765 creator A5082355132 @default.
- W1985014765 date "1996-11-01" @default.
- W1985014765 modified "2023-10-02" @default.
- W1985014765 title "Crystal Growth in Dental Enamel: the Role of Amelogenins and Albumin" @default.
- W1985014765 cites W1865778293 @default.
- W1985014765 cites W1983580095 @default.
- W1985014765 cites W1989407285 @default.
- W1985014765 cites W1999734730 @default.
- W1985014765 cites W2033079651 @default.
- W1985014765 cites W2042721113 @default.
- W1985014765 cites W2055547890 @default.
- W1985014765 cites W2068741867 @default.
- W1985014765 cites W2076318481 @default.
- W1985014765 cites W2083508618 @default.
- W1985014765 cites W2095557056 @default.
- W1985014765 cites W2100778510 @default.
- W1985014765 cites W2100837269 @default.
- W1985014765 cites W2101108802 @default.
- W1985014765 doi "https://doi.org/10.1177/08959374960100020901" @default.
- W1985014765 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9206334" @default.
- W1985014765 hasPublicationYear "1996" @default.
- W1985014765 type Work @default.
- W1985014765 sameAs 1985014765 @default.
- W1985014765 citedByCount "33" @default.
- W1985014765 countsByYear W19850147652012 @default.
- W1985014765 countsByYear W19850147652013 @default.
- W1985014765 countsByYear W19850147652014 @default.
- W1985014765 countsByYear W19850147652015 @default.
- W1985014765 countsByYear W19850147652019 @default.
- W1985014765 countsByYear W19850147652020 @default.
- W1985014765 countsByYear W19850147652021 @default.
- W1985014765 countsByYear W19850147652022 @default.
- W1985014765 countsByYear W19850147652023 @default.
- W1985014765 crossrefType "journal-article" @default.
- W1985014765 hasAuthorship W1985014765A5007086297 @default.
- W1985014765 hasAuthorship W1985014765A5012208618 @default.
- W1985014765 hasAuthorship W1985014765A5034470368 @default.
- W1985014765 hasAuthorship W1985014765A5062033888 @default.
- W1985014765 hasAuthorship W1985014765A5082355132 @default.
- W1985014765 hasConcept C106434640 @default.
- W1985014765 hasConcept C106487976 @default.
- W1985014765 hasConcept C12554922 @default.
- W1985014765 hasConcept C156887251 @default.
- W1985014765 hasConcept C185592680 @default.
- W1985014765 hasConcept C199106506 @default.
- W1985014765 hasConcept C199343813 @default.
- W1985014765 hasConcept C2776125364 @default.
- W1985014765 hasConcept C2777958113 @default.
- W1985014765 hasConcept C2910355441 @default.
- W1985014765 hasConcept C43617362 @default.
- W1985014765 hasConcept C55493867 @default.
- W1985014765 hasConcept C71924100 @default.
- W1985014765 hasConcept C86803240 @default.
- W1985014765 hasConceptScore W1985014765C106434640 @default.
- W1985014765 hasConceptScore W1985014765C106487976 @default.
- W1985014765 hasConceptScore W1985014765C12554922 @default.
- W1985014765 hasConceptScore W1985014765C156887251 @default.
- W1985014765 hasConceptScore W1985014765C185592680 @default.
- W1985014765 hasConceptScore W1985014765C199106506 @default.
- W1985014765 hasConceptScore W1985014765C199343813 @default.
- W1985014765 hasConceptScore W1985014765C2776125364 @default.
- W1985014765 hasConceptScore W1985014765C2777958113 @default.
- W1985014765 hasConceptScore W1985014765C2910355441 @default.
- W1985014765 hasConceptScore W1985014765C43617362 @default.
- W1985014765 hasConceptScore W1985014765C55493867 @default.
- W1985014765 hasConceptScore W1985014765C71924100 @default.
- W1985014765 hasConceptScore W1985014765C86803240 @default.
- W1985014765 hasIssue "2" @default.
- W1985014765 hasLocation W19850147651 @default.
- W1985014765 hasLocation W19850147652 @default.
- W1985014765 hasOpenAccess W1985014765 @default.
- W1985014765 hasPrimaryLocation W19850147651 @default.
- W1985014765 hasRelatedWork W1829427265 @default.
- W1985014765 hasRelatedWork W1872198448 @default.
- W1985014765 hasRelatedWork W1985014765 @default.
- W1985014765 hasRelatedWork W2030794193 @default.
- W1985014765 hasRelatedWork W2120426995 @default.
- W1985014765 hasRelatedWork W2168835276 @default.
- W1985014765 hasRelatedWork W2169923698 @default.
- W1985014765 hasRelatedWork W2411051586 @default.
- W1985014765 hasRelatedWork W2487684752 @default.
- W1985014765 hasRelatedWork W3197945074 @default.
- W1985014765 hasVolume "10" @default.
- W1985014765 isParatext "false" @default.
- W1985014765 isRetracted "false" @default.
- W1985014765 magId "1985014765" @default.
- W1985014765 workType "article" @default.