FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1985042222> ?p ?o ?g. }

• W1985042222 endingPage "206" @default.
• W1985042222 startingPage "188" @default.
• W1985042222 abstract "High-throughput molecular biology and crystallography advances have placed an increasing demand on crystallization, the one remaining bottleneck in macromolecular crystallography. This paper describes three experimental approaches, an incomplete factorial crystallization screen, a high-throughput nanoliter crystallization system, and the use of a neural net to predict crystallization conditions via a small sample (approximately 0.1%) of screening results. The use of these technologies has the potential to reduce time and sample requirements. Initial experimental results indicate that the incomplete factorial design detects initial crystallization conditions not previously discovered using commercial screens. This may be due to the ability of the incomplete factorial screen to sample a broader portion of crystallization space, using a multidimensional set of components, concentrations, and physical conditions. The incomplete factorial screen is complemented by a neural network program used to model crystallization. This capability is used to help predict new crystallization conditions. An automated, nanoliter crystallization system, with a throughput of up to 400 conditions/h in 40-nl droplets (total volume), accommodates microbatch or traditional sitting-drop vapor diffusion experiments. The goal of this research is to develop a fully-automated high-throughput crystallization system that integrates incomplete factorial screen and neural net capabilities." @default.
• W1985042222 created "2016-06-24" @default.
• W1985042222 creator A5002926154 @default.
• W1985042222 creator A5027723332 @default.
• W1985042222 creator A5032847009 @default.
• W1985042222 creator A5046135925 @default.
• W1985042222 creator A5061309007 @default.
• W1985042222 creator A5066650941 @default.
• W1985042222 creator A5069174677 @default.
• W1985042222 creator A5070126396 @default.
• W1985042222 creator A5075606749 @default.
• W1985042222 creator A5082366878 @default.
• W1985042222 date "2003-04-01" @default.
• W1985042222 modified "2023-09-23" @default.
• W1985042222 title "Efficient protein crystallization" @default.
• W1985042222 cites W1593022059 @default.
• W1985042222 cites W1598617551 @default.
• W1985042222 cites W1605936672 @default.
• W1985042222 cites W197287723 @default.
• W1985042222 cites W2001495906 @default.
• W1985042222 cites W2015654827 @default.
• W1985042222 cites W2015982647 @default.
• W1985042222 cites W2029657107 @default.
• W1985042222 cites W2033755819 @default.
• W1985042222 cites W2036883652 @default.
• W1985042222 cites W2055219658 @default.
• W1985042222 cites W2063241545 @default.
• W1985042222 cites W2064770256 @default.
• W1985042222 cites W2085253474 @default.
• W1985042222 cites W2085901859 @default.
• W1985042222 cites W2089143497 @default.
• W1985042222 cites W2094504398 @default.
• W1985042222 cites W2106741943 @default.
• W1985042222 cites W4251419681 @default.
• W1985042222 doi "https://doi.org/10.1016/s1047-8477(03)00050-9" @default.
• W1985042222 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12718931" @default.
• W1985042222 hasPublicationYear "2003" @default.
• W1985042222 type Work @default.
• W1985042222 sameAs 1985042222 @default.
• W1985042222 citedByCount "62" @default.
• W1985042222 countsByYear W19850422222012 @default.
• W1985042222 countsByYear W19850422222013 @default.
• W1985042222 countsByYear W19850422222014 @default.
• W1985042222 countsByYear W19850422222015 @default.
• W1985042222 countsByYear W19850422222016 @default.
• W1985042222 countsByYear W19850422222017 @default.
• W1985042222 countsByYear W19850422222018 @default.
• W1985042222 countsByYear W19850422222019 @default.
• W1985042222 countsByYear W19850422222020 @default.
• W1985042222 countsByYear W19850422222023 @default.
• W1985042222 crossrefType "journal-article" @default.
• W1985042222 hasAuthorship W1985042222A5002926154 @default.
• W1985042222 hasAuthorship W1985042222A5027723332 @default.
• W1985042222 hasAuthorship W1985042222A5032847009 @default.
• W1985042222 hasAuthorship W1985042222A5046135925 @default.
• W1985042222 hasAuthorship W1985042222A5061309007 @default.
• W1985042222 hasAuthorship W1985042222A5066650941 @default.
• W1985042222 hasAuthorship W1985042222A5069174677 @default.
• W1985042222 hasAuthorship W1985042222A5070126396 @default.
• W1985042222 hasAuthorship W1985042222A5075606749 @default.
• W1985042222 hasAuthorship W1985042222A5082366878 @default.
• W1985042222 hasConcept C119857082 @default.
• W1985042222 hasConcept C127413603 @default.
• W1985042222 hasConcept C134306372 @default.
• W1985042222 hasConcept C149635348 @default.
• W1985042222 hasConcept C153064111 @default.
• W1985042222 hasConcept C157764524 @default.
• W1985042222 hasConcept C16469947 @default.
• W1985042222 hasConcept C169222746 @default.
• W1985042222 hasConcept C183763347 @default.
• W1985042222 hasConcept C185592680 @default.
• W1985042222 hasConcept C186060115 @default.
• W1985042222 hasConcept C198531522 @default.
• W1985042222 hasConcept C203036418 @default.
• W1985042222 hasConcept C21880701 @default.
• W1985042222 hasConcept C2780513914 @default.
• W1985042222 hasConcept C33923547 @default.
• W1985042222 hasConcept C41008148 @default.
• W1985042222 hasConcept C42360764 @default.
• W1985042222 hasConcept C43617362 @default.
• W1985042222 hasConcept C555944384 @default.
• W1985042222 hasConcept C76155785 @default.
• W1985042222 hasConcept C86803240 @default.
• W1985042222 hasConceptScore W1985042222C119857082 @default.
• W1985042222 hasConceptScore W1985042222C127413603 @default.
• W1985042222 hasConceptScore W1985042222C134306372 @default.
• W1985042222 hasConceptScore W1985042222C149635348 @default.
• W1985042222 hasConceptScore W1985042222C153064111 @default.
• W1985042222 hasConceptScore W1985042222C157764524 @default.
• W1985042222 hasConceptScore W1985042222C16469947 @default.
• W1985042222 hasConceptScore W1985042222C169222746 @default.
• W1985042222 hasConceptScore W1985042222C183763347 @default.
• W1985042222 hasConceptScore W1985042222C185592680 @default.
• W1985042222 hasConceptScore W1985042222C186060115 @default.
• W1985042222 hasConceptScore W1985042222C198531522 @default.
• W1985042222 hasConceptScore W1985042222C203036418 @default.
• W1985042222 hasConceptScore W1985042222C21880701 @default.
• W1985042222 hasConceptScore W1985042222C2780513914 @default.

• next