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- W1985087083 endingPage "5048" @default.
- W1985087083 startingPage "5037" @default.
- W1985087083 abstract "DNA sequence analysis of the human β globin locus has identified an array of simple tandem repeated sequences upstream from the β globin structural gene. Comparison of several cloned human β globin alleles demonstrated a high frequency of sequence heteromorphism at this site apparently due to duplication or deletion of single units of the repeat array. At least two such duplication/deletion events are necessary to account for the observed variation. No other sequence variation was observed, suggesting that duplication/deletion events within the tandem repeat array may be at least 13 to 14 times more frequent than nucleotide substitutions in the surrounding DNA." @default.
- W1985087083 created "2016-06-24" @default.
- W1985087083 creator A5079793510 @default.
- W1985087083 date "1981-01-01" @default.
- W1985087083 modified "2023-09-30" @default.
- W1985087083 title "Duplication/deletion polymorphism 5′- to the human β globin gene" @default.
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- W1985087083 doi "https://doi.org/10.1093/nar/9.19.5037" @default.
- W1985087083 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/327497" @default.
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