Matches in SemOpenAlex for { <https://semopenalex.org/work/W1985087276> ?p ?o ?g. }
Showing items 1 to 90 of
90
with 100 items per page.
- W1985087276 endingPage "1906" @default.
- W1985087276 startingPage "1901" @default.
- W1985087276 abstract "A two-dimensional (2-D) Fourier-transform nuclear magnetic resonance (NMR) study of the 18 amino acid neurotoxin apamin isolated from honeybee venom is reported. Combining 2-D J-correlated spectra with 2-D nuclear Overhauser spectra in H2O solution permits essentially complete assignment of the 1H NMR spectrum of apamin at a fixed pH, including a number of spin systems that are reported for the first time. The structural model previously derived by Bystrov et al. [Bystrov, V. F., Okhanov, V. V., Miroshnikov, A. I., & Ovchinnikov, Yu. A. (1980) FEBS Lett. 119, 113-116] from NMR data is shown to be largely correct. The 2-D nuclear Overhauser effect (NOE) spectrum in particular reveals a series of amide-amide NOE's consistent with an alpha-helical core (residues 9-15) in the molecule. NOE's between amide and C alpha protons, followed by amide to amide NOE's, indicate a beta-turn involving residues 3-5 and a nonstandard turn including residues 6-8. We find no evidence for the beta-type structure postulated at the C terminus, however. Instead, it appears that the alpha-helix continues with increasing fraying from residues 16-18." @default.
- W1985087276 created "2016-06-24" @default.
- W1985087276 creator A5018742869 @default.
- W1985087276 creator A5039915636 @default.
- W1985087276 date "1983-04-12" @default.
- W1985087276 modified "2023-10-11" @default.
- W1985087276 title "Structure of apamin in solution: a two-dimensional nuclear magnetic resonance study" @default.
- W1985087276 cites W1484167309 @default.
- W1985087276 cites W1540949483 @default.
- W1985087276 cites W1584535589 @default.
- W1985087276 cites W1880112601 @default.
- W1985087276 cites W1967800362 @default.
- W1985087276 cites W1988121996 @default.
- W1985087276 cites W1989202801 @default.
- W1985087276 cites W2008632682 @default.
- W1985087276 cites W2008699893 @default.
- W1985087276 cites W2010528272 @default.
- W1985087276 cites W2012907151 @default.
- W1985087276 cites W2016706363 @default.
- W1985087276 cites W2020351375 @default.
- W1985087276 cites W2030901966 @default.
- W1985087276 cites W2036325594 @default.
- W1985087276 cites W2045446885 @default.
- W1985087276 cites W2074770586 @default.
- W1985087276 cites W2088194826 @default.
- W1985087276 cites W2095213663 @default.
- W1985087276 cites W2137870837 @default.
- W1985087276 doi "https://doi.org/10.1021/bi00277a025" @default.
- W1985087276 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6849893" @default.
- W1985087276 hasPublicationYear "1983" @default.
- W1985087276 type Work @default.
- W1985087276 sameAs 1985087276 @default.
- W1985087276 citedByCount "96" @default.
- W1985087276 countsByYear W19850872762013 @default.
- W1985087276 countsByYear W19850872762022 @default.
- W1985087276 crossrefType "journal-article" @default.
- W1985087276 hasAuthorship W1985087276A5018742869 @default.
- W1985087276 hasAuthorship W1985087276A5039915636 @default.
- W1985087276 hasConcept C119851462 @default.
- W1985087276 hasConcept C121332964 @default.
- W1985087276 hasConcept C1276947 @default.
- W1985087276 hasConcept C178790620 @default.
- W1985087276 hasConcept C185592680 @default.
- W1985087276 hasConcept C2776919887 @default.
- W1985087276 hasConcept C2778439535 @default.
- W1985087276 hasConcept C32909587 @default.
- W1985087276 hasConcept C46141821 @default.
- W1985087276 hasConcept C4839761 @default.
- W1985087276 hasConcept C519063684 @default.
- W1985087276 hasConcept C66974803 @default.
- W1985087276 hasConcept C67787023 @default.
- W1985087276 hasConcept C71240020 @default.
- W1985087276 hasConcept C8010536 @default.
- W1985087276 hasConceptScore W1985087276C119851462 @default.
- W1985087276 hasConceptScore W1985087276C121332964 @default.
- W1985087276 hasConceptScore W1985087276C1276947 @default.
- W1985087276 hasConceptScore W1985087276C178790620 @default.
- W1985087276 hasConceptScore W1985087276C185592680 @default.
- W1985087276 hasConceptScore W1985087276C2776919887 @default.
- W1985087276 hasConceptScore W1985087276C2778439535 @default.
- W1985087276 hasConceptScore W1985087276C32909587 @default.
- W1985087276 hasConceptScore W1985087276C46141821 @default.
- W1985087276 hasConceptScore W1985087276C4839761 @default.
- W1985087276 hasConceptScore W1985087276C519063684 @default.
- W1985087276 hasConceptScore W1985087276C66974803 @default.
- W1985087276 hasConceptScore W1985087276C67787023 @default.
- W1985087276 hasConceptScore W1985087276C71240020 @default.
- W1985087276 hasConceptScore W1985087276C8010536 @default.
- W1985087276 hasIssue "8" @default.
- W1985087276 hasLocation W19850872761 @default.
- W1985087276 hasLocation W19850872762 @default.
- W1985087276 hasOpenAccess W1985087276 @default.
- W1985087276 hasPrimaryLocation W19850872761 @default.
- W1985087276 hasRelatedWork W1517538992 @default.
- W1985087276 hasRelatedWork W1599055883 @default.
- W1985087276 hasRelatedWork W1989381856 @default.
- W1985087276 hasRelatedWork W1999832360 @default.
- W1985087276 hasRelatedWork W2032227844 @default.
- W1985087276 hasRelatedWork W2050144398 @default.
- W1985087276 hasRelatedWork W2051831970 @default.
- W1985087276 hasRelatedWork W2891301307 @default.
- W1985087276 hasRelatedWork W2923404749 @default.
- W1985087276 hasRelatedWork W3150982967 @default.
- W1985087276 hasVolume "22" @default.
- W1985087276 isParatext "false" @default.
- W1985087276 isRetracted "false" @default.
- W1985087276 magId "1985087276" @default.
- W1985087276 workType "article" @default.