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• W1985193048 abstract "S HOCK as a state or condition of the entire individual has been adequately described by various persons and even specifically defined by official committees, although not all the accepted definitions are identical. 1 Some differences in the listed alterations of specific physiological functions may be associated with the various precipitating causes, while others may arise from species differences or other biological characteristics of the individual concerned. In all cases regardless of the descriptive adjectives used to indicate the most probable cause such as hypovolemic, endotoxic, surgical or traumatic, the shocked condition represents a failing circulatory system that will not always respond to therapeutic procedures. No single or simple criterion exists that invariably predicts impending shock or the outcome of this shocked state. Thus the vascular alteration associated with shock serve to define the state itself and may represent neither the pathology development nor point the way to the prevention of its occurrence. Since shock, however caused, is characterized as a failure of the circulation to carry out its normal function, it is natural those interested either in explaining the underlying cause or preventing its development have been concerned with both the normal and the pathologic aspects of the circulation. The shock condition involves many facets of the organism and regardless of the amount of knowledge of an isolated segment, there are always some aspects of the integrated system, a component part or of some essential mechanism that is not sufficiently understood. With such a complex condition the investigator has difficulty in determining whether that modification of function he associates with the abnormal behavior is primary or secondary to the causative factor. The complexities of the situation have been discussed in the transactions of the 1951-1955 Macy Conference on Shock. :2 The circulation, or better the circulatory system, is composed of many parts each of which contributes one or more functional aspects to the systems activity. Although for convenience the activities of a particular part are frequently studied in great detail without too much consideration of the remaining parts involvement, it is the system that makes its contribution to the body economy as a unit. Thus, a change in a given parts activity may escape notice because the change is below the detection level with existing technics," @default.
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• W1985193048 date "1967-05-01" @default.
• W1985193048 modified "2023-09-26" @default.
• W1985193048 title "Physiological considerations of the microcirculation as related to shock" @default.
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• W1985193048 doi "https://doi.org/10.1016/s0033-0620(67)80009-4" @default.
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