FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1985203019> ?p ?o ?g. }

• W1985203019 endingPage "473" @default.
• W1985203019 startingPage "463" @default.
• W1985203019 abstract "We investigate the relationship between the microfilarial density in the skin and the burden of adult female Onchocerca volvulus by analysing pre-control nodulectomy data which allow for a direct approach, independent of exposure. The data of 169 patients in Burkina Faso and 182 patients in Liberia represent savannah and forest onchocerciasis in West Africa, respectively. Whereas in Burkina Faso, a saturating relationship between microfilarial density and worm burden suggests the operation of density-dependent processes within human hosts, the Liberian data show a linear relationship implying no density dependence. The differences may derive from differences between both parasite strains, i.e. the savannah or the forest strain of O. volvulus. Consistently for both parasite strains and independent of the worm burden, the microfilarial density increases with host age emphasising the concept of the acquisition of immunological tolerance. In male hosts in Liberia, the microfilarial density increases stronger with the worm burden than in female hosts, whereas such sex-specific differences cannot be found in Burkina Faso. In the methodological part of this investigation, we suggest the beta-distribution to be most appropriate for describing variability in microfilarial densities and we present an approach to consider the uncertainty in the adult parasite burden which cannot be determined precisely in helminth infections. Implications of density dependence are discussed with respect to immunological processes in the human host and with respect to the success of control programs. The relationships described show that regulatory processes between the parasite and the human host are multi-dimensional, operating within a high degree of biological variability." @default.
• W1985203019 created "2016-06-24" @default.
• W1985203019 creator A5000243582 @default.
• W1985203019 creator A5018478983 @default.
• W1985203019 creator A5021353271 @default.
• W1985203019 creator A5054139797 @default.
• W1985203019 creator A5078946299 @default.
• W1985203019 date "2004-03-01" @default.
• W1985203019 modified "2023-10-18" @default.
• W1985203019 title "The relationships between the burden of adult parasites, host age and the microfilarial density in human onchocerciasis" @default.
• W1985203019 cites W128481479 @default.
• W1985203019 cites W1977562003 @default.
• W1985203019 cites W1987247643 @default.
• W1985203019 cites W2001586346 @default.
• W1985203019 cites W2001693838 @default.
• W1985203019 cites W2010470756 @default.
• W1985203019 cites W2022252002 @default.
• W1985203019 cites W2028724191 @default.
• W1985203019 cites W2053702138 @default.
• W1985203019 cites W2056623977 @default.
• W1985203019 cites W2059023748 @default.
• W1985203019 cites W2068465203 @default.
• W1985203019 cites W2072657860 @default.
• W1985203019 cites W2090013225 @default.
• W1985203019 cites W2093388332 @default.
• W1985203019 cites W2102596258 @default.
• W1985203019 cites W2112720640 @default.
• W1985203019 cites W2115127297 @default.
• W1985203019 cites W2149162204 @default.
• W1985203019 cites W2162957902 @default.
• W1985203019 cites W2164506899 @default.
• W1985203019 cites W2169196260 @default.
• W1985203019 doi "https://doi.org/10.1016/j.ijpara.2003.11.008" @default.
• W1985203019 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15013736" @default.
• W1985203019 hasPublicationYear "2004" @default.
• W1985203019 type Work @default.
• W1985203019 sameAs 1985203019 @default.
• W1985203019 citedByCount "36" @default.
• W1985203019 countsByYear W19852030192012 @default.
• W1985203019 countsByYear W19852030192013 @default.
• W1985203019 countsByYear W19852030192014 @default.
• W1985203019 countsByYear W19852030192015 @default.
• W1985203019 countsByYear W19852030192016 @default.
• W1985203019 countsByYear W19852030192017 @default.
• W1985203019 countsByYear W19852030192019 @default.
• W1985203019 countsByYear W19852030192020 @default.
• W1985203019 countsByYear W19852030192021 @default.
• W1985203019 countsByYear W19852030192022 @default.
• W1985203019 countsByYear W19852030192023 @default.
• W1985203019 crossrefType "journal-article" @default.
• W1985203019 hasAuthorship W1985203019A5000243582 @default.
• W1985203019 hasAuthorship W1985203019A5018478983 @default.
• W1985203019 hasAuthorship W1985203019A5021353271 @default.
• W1985203019 hasAuthorship W1985203019A5054139797 @default.
• W1985203019 hasAuthorship W1985203019A5078946299 @default.
• W1985203019 hasConcept C126831891 @default.
• W1985203019 hasConcept C136764020 @default.
• W1985203019 hasConcept C165901193 @default.
• W1985203019 hasConcept C18903297 @default.
• W1985203019 hasConcept C203014093 @default.
• W1985203019 hasConcept C2779027325 @default.
• W1985203019 hasConcept C2779726973 @default.
• W1985203019 hasConcept C2780727990 @default.
• W1985203019 hasConcept C41008148 @default.
• W1985203019 hasConcept C71928629 @default.
• W1985203019 hasConcept C86803240 @default.
• W1985203019 hasConcept C90856448 @default.
• W1985203019 hasConceptScore W1985203019C126831891 @default.
• W1985203019 hasConceptScore W1985203019C136764020 @default.
• W1985203019 hasConceptScore W1985203019C165901193 @default.
• W1985203019 hasConceptScore W1985203019C18903297 @default.
• W1985203019 hasConceptScore W1985203019C203014093 @default.
• W1985203019 hasConceptScore W1985203019C2779027325 @default.
• W1985203019 hasConceptScore W1985203019C2779726973 @default.
• W1985203019 hasConceptScore W1985203019C2780727990 @default.
• W1985203019 hasConceptScore W1985203019C41008148 @default.
• W1985203019 hasConceptScore W1985203019C71928629 @default.
• W1985203019 hasConceptScore W1985203019C86803240 @default.
• W1985203019 hasConceptScore W1985203019C90856448 @default.
• W1985203019 hasIssue "4" @default.
• W1985203019 hasLocation W19852030191 @default.
• W1985203019 hasLocation W19852030192 @default.
• W1985203019 hasOpenAccess W1985203019 @default.
• W1985203019 hasPrimaryLocation W19852030191 @default.
• W1985203019 hasRelatedWork W1982137939 @default.
• W1985203019 hasRelatedWork W1996932890 @default.
• W1985203019 hasRelatedWork W2019714535 @default.
• W1985203019 hasRelatedWork W2031098625 @default.
• W1985203019 hasRelatedWork W2105758850 @default.
• W1985203019 hasRelatedWork W2114624351 @default.
• W1985203019 hasRelatedWork W2219085803 @default.
• W1985203019 hasRelatedWork W23951481 @default.
• W1985203019 hasRelatedWork W2395568156 @default.
• W1985203019 hasRelatedWork W2747873928 @default.
• W1985203019 hasVolume "34" @default.
• W1985203019 isParatext "false" @default.
• W1985203019 isRetracted "false" @default.
• W1985203019 magId "1985203019" @default.

• next