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- W1985203479 abstract "Kinetic parameters of the enzymes Mg 2+ -ATPase and (Na + + K + )-ATPase were studied in the platelet and erythrocyte membrane of patients suffering from depressive, manic-depressive, and schizophrenic disorders and of normal controls. Na + and K + concentrations for half-maximal activation of platelet and erythrocyte membrane (Na + + K + )-ATPase were also studied. The K m (apparent) for the enzymes with ATP as substrate and the K + concentration for half-maximal activation of platelet and erythrocyte membrane (Na + + K + )-ATPase were unaltered in these patients when compared to respective controls. The increased affinities for Na + in depressives and manic-depressives and the decreased affinities in schizophrenics may contribute to the enhanced or lowered activities of membrane (Na + + K + )-ATPase." @default.
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- W1985203479 date "1981-12-01" @default.
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- W1985203479 title "Altered kinetics of membrane ATPase in mental illness" @default.
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- W1985203479 doi "https://doi.org/10.1016/0006-2944(81)90002-8" @default.
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