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- W1985221317 endingPage "117" @default.
- W1985221317 startingPage "108" @default.
- W1985221317 abstract "Hepatitis C virus (HCV) infection is a major and growing global health problem, affecting about 170 million people worldwide, and is a leading cause of liver cirrhosis and hepatocellular carcinoma. Currently, treatment is restricted to interferon alfa and ribavirin, which leads to a successful outcome in only about 50% of individuals. New effective treatments with tolerable side-effect profiles are needed urgently, but development has been hindered by an inability to culture HCV and a scarcity of animal models. Herein, we review progress in HCV biology, including cell culture and new animal models, and the contribution of this work to our understanding of the virus' life-cycle and pathogenesis and development of specifically targeted antiviral treatment. We also discuss changes in our understanding of HCV epidemiology, clinical manifestations, and diagnostics." @default.
- W1985221317 created "2016-06-24" @default.
- W1985221317 creator A5010873271 @default.
- W1985221317 creator A5027455759 @default.
- W1985221317 creator A5029546143 @default.
- W1985221317 creator A5057673896 @default.
- W1985221317 date "2009-02-01" @default.
- W1985221317 modified "2023-09-27" @default.
- W1985221317 title "Development of novel treatments for hepatitis C" @default.
- W1985221317 cites W1488480791 @default.
- W1985221317 cites W1544842645 @default.
- W1985221317 cites W1593744374 @default.
- W1985221317 cites W1611419331 @default.
- W1985221317 cites W1673662691 @default.
- W1985221317 cites W1928472258 @default.
- W1985221317 cites W1964568601 @default.
- W1985221317 cites W1964786592 @default.
- W1985221317 cites W1964963193 @default.
- W1985221317 cites W1965396914 @default.
- W1985221317 cites W1965813400 @default.
- W1985221317 cites W1965962980 @default.
- W1985221317 cites W1966241031 @default.
- W1985221317 cites W1966707343 @default.
- W1985221317 cites W1966780618 @default.
- W1985221317 cites W1967568821 @default.
- W1985221317 cites W1967653165 @default.
- W1985221317 cites W1967946955 @default.
- W1985221317 cites W1970561614 @default.
- W1985221317 cites W1973376188 @default.
- W1985221317 cites W1982977346 @default.
- W1985221317 cites W1985130564 @default.
- W1985221317 cites W1985680307 @default.
- W1985221317 cites W1991224416 @default.
- W1985221317 cites W1992239172 @default.
- W1985221317 cites W1994650906 @default.
- W1985221317 cites W1994923672 @default.
- W1985221317 cites W1998256358 @default.
- W1985221317 cites W19985279 @default.
- W1985221317 cites W1999487724 @default.
- W1985221317 cites W2000336618 @default.
- W1985221317 cites W2000756633 @default.
- W1985221317 cites W2002282552 @default.
- W1985221317 cites W2003579943 @default.
- W1985221317 cites W2004360699 @default.
- W1985221317 cites W2005692869 @default.
- W1985221317 cites W2007974735 @default.
- W1985221317 cites W2008885090 @default.
- W1985221317 cites W2015336471 @default.
- W1985221317 cites W2015533723 @default.
- W1985221317 cites W2017960775 @default.
- W1985221317 cites W2018196002 @default.
- W1985221317 cites W2018427484 @default.
- W1985221317 cites W2024049300 @default.
- W1985221317 cites W2027545702 @default.
- W1985221317 cites W2031477951 @default.
- W1985221317 cites W2036970411 @default.
- W1985221317 cites W2037686553 @default.
- W1985221317 cites W2042994480 @default.
- W1985221317 cites W2046858735 @default.
- W1985221317 cites W2048974214 @default.
- W1985221317 cites W2051984446 @default.
- W1985221317 cites W2052169811 @default.
- W1985221317 cites W2055828992 @default.
- W1985221317 cites W2056179599 @default.
- W1985221317 cites W2059402405 @default.
- W1985221317 cites W2059638323 @default.
- W1985221317 cites W2060483294 @default.
- W1985221317 cites W2062563125 @default.
- W1985221317 cites W2063592914 @default.
- W1985221317 cites W2065983650 @default.
- W1985221317 cites W2067263840 @default.
- W1985221317 cites W2070347865 @default.
- W1985221317 cites W2071586067 @default.
- W1985221317 cites W2073657821 @default.
- W1985221317 cites W2075147482 @default.
- W1985221317 cites W2076559408 @default.
- W1985221317 cites W2078145079 @default.
- W1985221317 cites W2079835503 @default.
- W1985221317 cites W2085604315 @default.
- W1985221317 cites W2086641001 @default.
- W1985221317 cites W2092244766 @default.
- W1985221317 cites W2095563205 @default.
- W1985221317 cites W2095582889 @default.
- W1985221317 cites W2096934958 @default.
- W1985221317 cites W2097246425 @default.
- W1985221317 cites W2097641909 @default.
- W1985221317 cites W2101494451 @default.
- W1985221317 cites W2103185551 @default.
- W1985221317 cites W2103529803 @default.
- W1985221317 cites W2105605655 @default.
- W1985221317 cites W2107175809 @default.
- W1985221317 cites W2108639262 @default.
- W1985221317 cites W2110842901 @default.
- W1985221317 cites W2111359040 @default.
- W1985221317 cites W2112876622 @default.
- W1985221317 cites W2113154128 @default.
- W1985221317 cites W2113183292 @default.
- W1985221317 cites W2113750591 @default.