Matches in SemOpenAlex for { <https://semopenalex.org/work/W1985221567> ?p ?o ?g. }
- W1985221567 endingPage "1181" @default.
- W1985221567 startingPage "1179" @default.
- W1985221567 abstract "Two markers of neuronal plasticity were used to compare the response of the human central nervous system to neuronal loss resulting from Alzheimer's disease with the response of rats to a similar neuronal loss induced by lesions. In rats that had received lesions of the entorhinal cortex, axon sprouting of commissural and associational fibers into the denervated molecular layer of the dentate gyrus was paralleled by a spread in the distribution of tritiated kainic acid-binding sites. A similar expansion of kainic acid receptor distribution was observed in hippocampal samples obtained postmortem from patients with Alzheimer's disease. An enhancement of acetylcholinesterase activity in the dentate gyrus molecular layer, indicative of septal afferent sprouting, was also observed in those patients with a minimal loss of cholinergic neurons. These results are evidence that the central nervous system is capable of a plastic response in Alzheimer's disease. Adaptive growth responses occur along with the degenerative events." @default.
- W1985221567 created "2016-06-24" @default.
- W1985221567 creator A5003994463 @default.
- W1985221567 creator A5026305547 @default.
- W1985221567 creator A5032570790 @default.
- W1985221567 creator A5042844182 @default.
- W1985221567 creator A5059339971 @default.
- W1985221567 creator A5090002053 @default.
- W1985221567 date "1985-12-06" @default.
- W1985221567 modified "2023-10-15" @default.
- W1985221567 title "Plasticity of Hippocampal Circuitry in Alzheimer's Disease" @default.
- W1985221567 cites W143851981 @default.
- W1985221567 cites W1897632924 @default.
- W1985221567 cites W1966027175 @default.
- W1985221567 cites W1970377013 @default.
- W1985221567 cites W1973429181 @default.
- W1985221567 cites W1974528959 @default.
- W1985221567 cites W1987438294 @default.
- W1985221567 cites W1987881101 @default.
- W1985221567 cites W1988270870 @default.
- W1985221567 cites W2006411038 @default.
- W1985221567 cites W2018041359 @default.
- W1985221567 cites W2019997262 @default.
- W1985221567 cites W2021280501 @default.
- W1985221567 cites W2021897005 @default.
- W1985221567 cites W2026643535 @default.
- W1985221567 cites W2027799011 @default.
- W1985221567 cites W2027925784 @default.
- W1985221567 cites W2028394019 @default.
- W1985221567 cites W2032768837 @default.
- W1985221567 cites W2033041856 @default.
- W1985221567 cites W2042109148 @default.
- W1985221567 cites W2043604149 @default.
- W1985221567 cites W2044899556 @default.
- W1985221567 cites W2048800757 @default.
- W1985221567 cites W2050324613 @default.
- W1985221567 cites W2051267844 @default.
- W1985221567 cites W2053116984 @default.
- W1985221567 cites W2053889928 @default.
- W1985221567 cites W2057473661 @default.
- W1985221567 cites W2061718284 @default.
- W1985221567 cites W2070114283 @default.
- W1985221567 cites W2071280637 @default.
- W1985221567 cites W2074971623 @default.
- W1985221567 cites W2080275842 @default.
- W1985221567 cites W2085143776 @default.
- W1985221567 cites W2093374391 @default.
- W1985221567 cites W2095828172 @default.
- W1985221567 cites W2096047338 @default.
- W1985221567 cites W2105766920 @default.
- W1985221567 cites W2109523793 @default.
- W1985221567 cites W2114129147 @default.
- W1985221567 cites W2120115883 @default.
- W1985221567 cites W2124973871 @default.
- W1985221567 cites W2126974689 @default.
- W1985221567 cites W2151347605 @default.
- W1985221567 cites W2162298355 @default.
- W1985221567 cites W2444475331 @default.
- W1985221567 doi "https://doi.org/10.1126/science.4071042" @default.
- W1985221567 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/4071042" @default.
- W1985221567 hasPublicationYear "1985" @default.
- W1985221567 type Work @default.
- W1985221567 sameAs 1985221567 @default.
- W1985221567 citedByCount "445" @default.
- W1985221567 countsByYear W19852215672012 @default.
- W1985221567 countsByYear W19852215672013 @default.
- W1985221567 countsByYear W19852215672014 @default.
- W1985221567 countsByYear W19852215672015 @default.
- W1985221567 countsByYear W19852215672016 @default.
- W1985221567 countsByYear W19852215672017 @default.
- W1985221567 countsByYear W19852215672018 @default.
- W1985221567 countsByYear W19852215672019 @default.
- W1985221567 countsByYear W19852215672020 @default.
- W1985221567 countsByYear W19852215672021 @default.
- W1985221567 countsByYear W19852215672022 @default.
- W1985221567 countsByYear W19852215672023 @default.
- W1985221567 crossrefType "journal-article" @default.
- W1985221567 hasAuthorship W1985221567A5003994463 @default.
- W1985221567 hasAuthorship W1985221567A5026305547 @default.
- W1985221567 hasAuthorship W1985221567A5032570790 @default.
- W1985221567 hasAuthorship W1985221567A5042844182 @default.
- W1985221567 hasAuthorship W1985221567A5059339971 @default.
- W1985221567 hasAuthorship W1985221567A5090002053 @default.
- W1985221567 hasConcept C142724271 @default.
- W1985221567 hasConcept C148762608 @default.
- W1985221567 hasConcept C169760540 @default.
- W1985221567 hasConcept C170493617 @default.
- W1985221567 hasConcept C22885893 @default.
- W1985221567 hasConcept C2776108384 @default.
- W1985221567 hasConcept C2776464000 @default.
- W1985221567 hasConcept C2778241760 @default.
- W1985221567 hasConcept C2779134260 @default.
- W1985221567 hasConcept C2779530196 @default.
- W1985221567 hasConcept C2780715579 @default.
- W1985221567 hasConcept C2781161787 @default.
- W1985221567 hasConcept C47611674 @default.
- W1985221567 hasConcept C502032728 @default.
- W1985221567 hasConcept C529278444 @default.