Matches in SemOpenAlex for { <https://semopenalex.org/work/W19852249> ?p ?o ?g. }
Showing items 1 to 96 of
96
with 100 items per page.
- W19852249 abstract "The recA gene product from E. coli plays a central role in two major functions which are essential to the bacterium life: i) it catalyzes general genetic recombination by promoting DNA strand exchange reactions. In vitro it has been shown that RecA protein catalyzes the formation of duplex DNA from complementary single-stranded molecules (annealing), the assimilation of linear single-strands into duplex circular DNA to form D-loops, the pairing of gapped circular DNA with either superhelical or nicked circular DNA, the complete exchange of strands between full length linear duplex and homologous circular single-stranded DNA. D-loop formation requires ATP but not its hydrolysis whereas extension of an heteroduplex via branch migration requires ATP hydrolysis and proceeds with a unique polarity (for review see references 1,2); ii) the recA gene product plays a crucial role in DNA repair. When DNA replication is perturbed either as a consequence of damages induced in DNA by physical (radiations) or chemical agents, or by an alteration of the replication fork, a series of genes called the “SOS genes” are derepressed. These genes are under the control of a common repressor, the lexA gene product, which is cleaved by the RecA protein. This proteolytic activity of the RecA protein is induced when it binds to single-stranded DNA in the presence of ATP, even though ATP hydrolysis is not required for the cleavage reaction (for review see reference 3)." @default.
- W19852249 created "2016-06-24" @default.
- W19852249 creator A5023901131 @default.
- W19852249 creator A5045874815 @default.
- W19852249 creator A5062607453 @default.
- W19852249 creator A5066290057 @default.
- W19852249 date "1983-01-01" @default.
- W19852249 modified "2023-09-25" @default.
- W19852249 title "The recA Gene Product from E. coli. Binding to Single-Stranded and Double-Stranded DNA" @default.
- W19852249 cites W1835632918 @default.
- W19852249 cites W2023253026 @default.
- W19852249 cites W2024007811 @default.
- W19852249 cites W2028544954 @default.
- W19852249 cites W2048815689 @default.
- W19852249 cites W2064786741 @default.
- W19852249 cites W2070810615 @default.
- W19852249 cites W2081480712 @default.
- W19852249 cites W2089312078 @default.
- W19852249 cites W2090357496 @default.
- W19852249 cites W2109646840 @default.
- W19852249 cites W2173708640 @default.
- W19852249 doi "https://doi.org/10.1007/978-94-009-7225-4_22" @default.
- W19852249 hasPublicationYear "1983" @default.
- W19852249 type Work @default.
- W19852249 sameAs 19852249 @default.
- W19852249 citedByCount "0" @default.
- W19852249 crossrefType "book-chapter" @default.
- W19852249 hasAuthorship W19852249A5023901131 @default.
- W19852249 hasAuthorship W19852249A5045874815 @default.
- W19852249 hasAuthorship W19852249A5062607453 @default.
- W19852249 hasAuthorship W19852249A5066290057 @default.
- W19852249 hasConcept C104317684 @default.
- W19852249 hasConcept C113271649 @default.
- W19852249 hasConcept C134494468 @default.
- W19852249 hasConcept C150194340 @default.
- W19852249 hasConcept C153911025 @default.
- W19852249 hasConcept C156719811 @default.
- W19852249 hasConcept C185592680 @default.
- W19852249 hasConcept C194830204 @default.
- W19852249 hasConcept C19924922 @default.
- W19852249 hasConcept C203284983 @default.
- W19852249 hasConcept C31254050 @default.
- W19852249 hasConcept C552990157 @default.
- W19852249 hasConcept C55493867 @default.
- W19852249 hasConcept C58167604 @default.
- W19852249 hasConcept C67705224 @default.
- W19852249 hasConcept C73573662 @default.
- W19852249 hasConcept C86339819 @default.
- W19852249 hasConcept C86803240 @default.
- W19852249 hasConcept C94966510 @default.
- W19852249 hasConceptScore W19852249C104317684 @default.
- W19852249 hasConceptScore W19852249C113271649 @default.
- W19852249 hasConceptScore W19852249C134494468 @default.
- W19852249 hasConceptScore W19852249C150194340 @default.
- W19852249 hasConceptScore W19852249C153911025 @default.
- W19852249 hasConceptScore W19852249C156719811 @default.
- W19852249 hasConceptScore W19852249C185592680 @default.
- W19852249 hasConceptScore W19852249C194830204 @default.
- W19852249 hasConceptScore W19852249C19924922 @default.
- W19852249 hasConceptScore W19852249C203284983 @default.
- W19852249 hasConceptScore W19852249C31254050 @default.
- W19852249 hasConceptScore W19852249C552990157 @default.
- W19852249 hasConceptScore W19852249C55493867 @default.
- W19852249 hasConceptScore W19852249C58167604 @default.
- W19852249 hasConceptScore W19852249C67705224 @default.
- W19852249 hasConceptScore W19852249C73573662 @default.
- W19852249 hasConceptScore W19852249C86339819 @default.
- W19852249 hasConceptScore W19852249C86803240 @default.
- W19852249 hasConceptScore W19852249C94966510 @default.
- W19852249 hasLocation W198522491 @default.
- W19852249 hasOpenAccess W19852249 @default.
- W19852249 hasPrimaryLocation W198522491 @default.
- W19852249 hasRelatedWork W1019437562 @default.
- W19852249 hasRelatedWork W1510960581 @default.
- W19852249 hasRelatedWork W1526656863 @default.
- W19852249 hasRelatedWork W1546428176 @default.
- W19852249 hasRelatedWork W1552082201 @default.
- W19852249 hasRelatedWork W1591316722 @default.
- W19852249 hasRelatedWork W1969903652 @default.
- W19852249 hasRelatedWork W1971198145 @default.
- W19852249 hasRelatedWork W1998449586 @default.
- W19852249 hasRelatedWork W2008377571 @default.
- W19852249 hasRelatedWork W2017059201 @default.
- W19852249 hasRelatedWork W2024335194 @default.
- W19852249 hasRelatedWork W2079866816 @default.
- W19852249 hasRelatedWork W2089312078 @default.
- W19852249 hasRelatedWork W2098865666 @default.
- W19852249 hasRelatedWork W2114476141 @default.
- W19852249 hasRelatedWork W2124391709 @default.
- W19852249 hasRelatedWork W2171215766 @default.
- W19852249 hasRelatedWork W2976374498 @default.
- W19852249 hasRelatedWork W2114950095 @default.
- W19852249 isParatext "false" @default.
- W19852249 isRetracted "false" @default.
- W19852249 magId "19852249" @default.
- W19852249 workType "book-chapter" @default.