Matches in SemOpenAlex for { <https://semopenalex.org/work/W1985319910> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W1985319910 endingPage "1185" @default.
- W1985319910 startingPage "1173" @default.
- W1985319910 abstract "The efficacy and safety of a new slowrelease formulation of nifedipine (“Adalat Retard”) were assessed in a double-blind cross-over trial in 19 subjects with essential hypertension (14 male, 5 female—ages: 34–72 years), 14 of whom continued previous antihypertensive medication. There were two 6 week treatment phases in which nifedipine 20 mg twice daily and placebo tablets twice daily were administered in random order. Supine mean blood pressure was 115 ± 2 mm Hg during the placebo phase and 105 ± 2 mm Hg during the nifedipine phase (p < 0.001); and standing mean blood pressure was 121 ± 2 mm Hg after placebo and 110 ± 2 mm Hg after nifedipine (p < 0.001). The magnitude of the blood pressure difference between the two phases was not related either to age or to the placebo phase blood pressure. The hypotensive effect of nifedipine was observed when administered as a single agent or in combination with diuretic and/or beta blocker. Heart rate was increased after nifedipine −75 ±2 beats/minute compared with 71 ± 2 beats/minute after placebo (p < 0.01). In this dose nifedipine (as “Adalat Retard”) is an effective hypotensive agent which is a useful addition to presently available therapy." @default.
- W1985319910 created "2016-06-24" @default.
- W1985319910 creator A5000069843 @default.
- W1985319910 creator A5051108336 @default.
- W1985319910 creator A5053067152 @default.
- W1985319910 creator A5055394217 @default.
- W1985319910 date "1985-01-01" @default.
- W1985319910 modified "2023-10-17" @default.
- W1985319910 title "Slow-Release Nifedipine as a Single or Additional Agent in the Treatment of Essential Hypertension—A Placebo-Controlled Crossover Study" @default.
- W1985319910 cites W1965094135 @default.
- W1985319910 cites W1995103639 @default.
- W1985319910 cites W1997481647 @default.
- W1985319910 cites W2013688307 @default.
- W1985319910 cites W2015145900 @default.
- W1985319910 cites W2029630909 @default.
- W1985319910 cites W2045098641 @default.
- W1985319910 cites W2045366964 @default.
- W1985319910 cites W2048223496 @default.
- W1985319910 cites W2051306237 @default.
- W1985319910 cites W2062561387 @default.
- W1985319910 cites W2066713394 @default.
- W1985319910 cites W2071092830 @default.
- W1985319910 cites W2079432797 @default.
- W1985319910 cites W2083005028 @default.
- W1985319910 cites W2083513135 @default.
- W1985319910 cites W2086577738 @default.
- W1985319910 cites W2093495045 @default.
- W1985319910 cites W2110757641 @default.
- W1985319910 cites W2113303181 @default.
- W1985319910 cites W2138461535 @default.
- W1985319910 cites W2138613293 @default.
- W1985319910 cites W2411953863 @default.
- W1985319910 doi "https://doi.org/10.3109/10641968509073583" @default.
- W1985319910 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/4042390" @default.
- W1985319910 hasPublicationYear "1985" @default.
- W1985319910 type Work @default.
- W1985319910 sameAs 1985319910 @default.
- W1985319910 citedByCount "3" @default.
- W1985319910 crossrefType "journal-article" @default.
- W1985319910 hasAuthorship W1985319910A5000069843 @default.
- W1985319910 hasAuthorship W1985319910A5051108336 @default.
- W1985319910 hasAuthorship W1985319910A5053067152 @default.
- W1985319910 hasAuthorship W1985319910A5055394217 @default.
- W1985319910 hasConcept C125567185 @default.
- W1985319910 hasConcept C126322002 @default.
- W1985319910 hasConcept C142724271 @default.
- W1985319910 hasConcept C204787440 @default.
- W1985319910 hasConcept C27081682 @default.
- W1985319910 hasConcept C2777097880 @default.
- W1985319910 hasConcept C2777953023 @default.
- W1985319910 hasConcept C2779066535 @default.
- W1985319910 hasConcept C2779918671 @default.
- W1985319910 hasConcept C42219234 @default.
- W1985319910 hasConcept C519063684 @default.
- W1985319910 hasConcept C71924100 @default.
- W1985319910 hasConcept C84393581 @default.
- W1985319910 hasConcept C87813604 @default.
- W1985319910 hasConcept C98274493 @default.
- W1985319910 hasConceptScore W1985319910C125567185 @default.
- W1985319910 hasConceptScore W1985319910C126322002 @default.
- W1985319910 hasConceptScore W1985319910C142724271 @default.
- W1985319910 hasConceptScore W1985319910C204787440 @default.
- W1985319910 hasConceptScore W1985319910C27081682 @default.
- W1985319910 hasConceptScore W1985319910C2777097880 @default.
- W1985319910 hasConceptScore W1985319910C2777953023 @default.
- W1985319910 hasConceptScore W1985319910C2779066535 @default.
- W1985319910 hasConceptScore W1985319910C2779918671 @default.
- W1985319910 hasConceptScore W1985319910C42219234 @default.
- W1985319910 hasConceptScore W1985319910C519063684 @default.
- W1985319910 hasConceptScore W1985319910C71924100 @default.
- W1985319910 hasConceptScore W1985319910C84393581 @default.
- W1985319910 hasConceptScore W1985319910C87813604 @default.
- W1985319910 hasConceptScore W1985319910C98274493 @default.
- W1985319910 hasIssue "8" @default.
- W1985319910 hasLocation W19853199101 @default.
- W1985319910 hasLocation W19853199102 @default.
- W1985319910 hasOpenAccess W1985319910 @default.
- W1985319910 hasPrimaryLocation W19853199101 @default.
- W1985319910 hasRelatedWork W1964382309 @default.
- W1985319910 hasRelatedWork W1978419310 @default.
- W1985319910 hasRelatedWork W1985319910 @default.
- W1985319910 hasRelatedWork W2004716117 @default.
- W1985319910 hasRelatedWork W2040846565 @default.
- W1985319910 hasRelatedWork W2055279203 @default.
- W1985319910 hasRelatedWork W2103832820 @default.
- W1985319910 hasRelatedWork W2119698783 @default.
- W1985319910 hasRelatedWork W73303660 @default.
- W1985319910 hasRelatedWork W82813214 @default.
- W1985319910 hasVolume "7" @default.
- W1985319910 isParatext "false" @default.
- W1985319910 isRetracted "false" @default.
- W1985319910 magId "1985319910" @default.
- W1985319910 workType "article" @default.