Matches in SemOpenAlex for { <https://semopenalex.org/work/W198532174> ?p ?o ?g. }
- W198532174 endingPage "401" @default.
- W198532174 startingPage "391" @default.
- W198532174 abstract "Serotonin (5-HT) and voltage-gated potassium (KV) channels have emerged as two major factors in the pathogenesis of pulmonary arterial hypertension (PAH). In pulmonary artery smooth muscle cells (PASMC), KV channels play a major role in the regulation of pulmonary arterial tone and proliferation. Thus, activation of KV channels leads to vasodilatation and enhances apoptosis, while their inhibition is associated with vasoconstriction and proliferation in PASMC. Moreover, these channels have a prominent role as a common target for pulmonary vasoconstrictors. Modulation of these channels by vasoconstrictors involves the activation of a variety of protein kinases. Here we review the role of localization and internalization as a novel mechanism for acute regulation of KV channels and pulmonary vascular tone by agonists such as serotonin." @default.
- W198532174 created "2016-06-24" @default.
- W198532174 creator A5071640634 @default.
- W198532174 creator A5091585058 @default.
- W198532174 date "2009-12-26" @default.
- W198532174 modified "2023-10-18" @default.
- W198532174 title "5-HT Receptors and KV Channel Internalization" @default.
- W198532174 cites W1499833703 @default.
- W198532174 cites W1508637730 @default.
- W198532174 cites W1967776802 @default.
- W198532174 cites W1980619986 @default.
- W198532174 cites W1982885166 @default.
- W198532174 cites W1988483987 @default.
- W198532174 cites W1996588278 @default.
- W198532174 cites W1998223482 @default.
- W198532174 cites W2003831717 @default.
- W198532174 cites W2006355149 @default.
- W198532174 cites W2009959265 @default.
- W198532174 cites W2011985298 @default.
- W198532174 cites W2014609720 @default.
- W198532174 cites W2015390870 @default.
- W198532174 cites W2023167197 @default.
- W198532174 cites W2025593289 @default.
- W198532174 cites W2036507117 @default.
- W198532174 cites W2039765797 @default.
- W198532174 cites W2050099786 @default.
- W198532174 cites W2052716105 @default.
- W198532174 cites W2056199772 @default.
- W198532174 cites W2060620863 @default.
- W198532174 cites W2076273085 @default.
- W198532174 cites W2079219474 @default.
- W198532174 cites W2084925375 @default.
- W198532174 cites W2091638984 @default.
- W198532174 cites W2096605551 @default.
- W198532174 cites W2099934410 @default.
- W198532174 cites W2100246616 @default.
- W198532174 cites W2103424889 @default.
- W198532174 cites W2118033887 @default.
- W198532174 cites W2127555203 @default.
- W198532174 cites W2128937433 @default.
- W198532174 cites W2136306939 @default.
- W198532174 cites W2139960175 @default.
- W198532174 cites W2140879697 @default.
- W198532174 cites W2146609872 @default.
- W198532174 cites W2150930622 @default.
- W198532174 cites W2151082960 @default.
- W198532174 cites W2155641634 @default.
- W198532174 cites W2162973968 @default.
- W198532174 cites W2163394057 @default.
- W198532174 cites W2164602156 @default.
- W198532174 cites W2166972132 @default.
- W198532174 cites W2166985476 @default.
- W198532174 cites W2419424321 @default.
- W198532174 cites W4230841938 @default.
- W198532174 doi "https://doi.org/10.1007/978-1-60761-500-2_25" @default.
- W198532174 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20204744" @default.
- W198532174 hasPublicationYear "2009" @default.
- W198532174 type Work @default.
- W198532174 sameAs 198532174 @default.
- W198532174 citedByCount "3" @default.
- W198532174 countsByYear W1985321742018 @default.
- W198532174 countsByYear W1985321742021 @default.
- W198532174 crossrefType "book-chapter" @default.
- W198532174 hasAuthorship W198532174A5071640634 @default.
- W198532174 hasAuthorship W198532174A5091585058 @default.
- W198532174 hasConcept C120770815 @default.
- W198532174 hasConcept C126322002 @default.
- W198532174 hasConcept C139770010 @default.
- W198532174 hasConcept C170493617 @default.
- W198532174 hasConcept C2775864247 @default.
- W198532174 hasConcept C2779395532 @default.
- W198532174 hasConcept C2779961880 @default.
- W198532174 hasConcept C2780940725 @default.
- W198532174 hasConcept C29323129 @default.
- W198532174 hasConcept C2992686903 @default.
- W198532174 hasConcept C53910766 @default.
- W198532174 hasConcept C71924100 @default.
- W198532174 hasConcept C83743174 @default.
- W198532174 hasConceptScore W198532174C120770815 @default.
- W198532174 hasConceptScore W198532174C126322002 @default.
- W198532174 hasConceptScore W198532174C139770010 @default.
- W198532174 hasConceptScore W198532174C170493617 @default.
- W198532174 hasConceptScore W198532174C2775864247 @default.
- W198532174 hasConceptScore W198532174C2779395532 @default.
- W198532174 hasConceptScore W198532174C2779961880 @default.
- W198532174 hasConceptScore W198532174C2780940725 @default.
- W198532174 hasConceptScore W198532174C29323129 @default.
- W198532174 hasConceptScore W198532174C2992686903 @default.
- W198532174 hasConceptScore W198532174C53910766 @default.
- W198532174 hasConceptScore W198532174C71924100 @default.
- W198532174 hasConceptScore W198532174C83743174 @default.
- W198532174 hasLocation W1985321741 @default.
- W198532174 hasLocation W1985321742 @default.
- W198532174 hasOpenAccess W198532174 @default.
- W198532174 hasPrimaryLocation W1985321741 @default.
- W198532174 hasRelatedWork W1515836815 @default.
- W198532174 hasRelatedWork W153398559 @default.
- W198532174 hasRelatedWork W1982454194 @default.