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- W1985357723 abstract "The influenza viral membrane protein hemagglutinin (HA) is required at high concentrations on virion and host-cell membranes for infectivity. Because the role of actin in membrane organization is not completely understood, we quantified the relationship between HA and host-cell actin at the nanoscale. Results obtained using superresolution fluorescence photoactivation localization microscopy (FPALM) in nonpolarized cells show that HA clusters colocalize with actin-rich membrane regions (ARMRs). Individual molecular trajectories in live cells indicate restricted HA mobility in ARMRs, and actin disruption caused specific changes to HA clustering. Surprisingly, the actin-binding protein cofilin was excluded from some regions within several hundred nanometers of HA clusters, suggesting that HA clusters or adjacent proteins within the same clusters influence local actin structure. Thus, with the use of imaging, we demonstrate a dynamic relationship between glycoprotein membrane organization and the actin cytoskeleton at the nanoscale." @default.
- W1985357723 created "2016-06-24" @default.
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- W1985357723 date "2013-05-01" @default.
- W1985357723 modified "2023-10-08" @default.
- W1985357723 title "Actin Mediates the Nanoscale Membrane Organization of the Clustered Membrane Protein Influenza Hemagglutinin" @default.
- W1985357723 cites W1484094963 @default.
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- W1985357723 cites W1987717533 @default.
- W1985357723 cites W1993544865 @default.
- W1985357723 cites W1994113357 @default.
- W1985357723 cites W1997089381 @default.
- W1985357723 cites W2001678988 @default.
- W1985357723 cites W2002478108 @default.
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- W1985357723 cites W2007012258 @default.
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- W1985357723 cites W2129769231 @default.
- W1985357723 cites W2133087541 @default.
- W1985357723 cites W2144438046 @default.
- W1985357723 cites W2146255300 @default.
- W1985357723 cites W2149850870 @default.
- W1985357723 cites W2150141558 @default.
- W1985357723 cites W2154744729 @default.
- W1985357723 cites W2154827556 @default.
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- W1985357723 doi "https://doi.org/10.1016/j.bpj.2013.03.054" @default.
- W1985357723 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3660645" @default.
- W1985357723 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23708358" @default.
- W1985357723 hasPublicationYear "2013" @default.
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