Matches in SemOpenAlex for { <https://semopenalex.org/work/W1985384321> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W1985384321 endingPage "e64068" @default.
- W1985384321 startingPage "e64068" @default.
- W1985384321 abstract "We have identified a natural clay mixture that exhibits in vitro antibacterial activity against a broad spectrum of bacterial pathogens. We collected four samples from the same source and demonstrated through antibacterial susceptibility testing that these clay mixtures have markedly different antibacterial activity against Escherichia coli and methicillin-resistant Staphylococcus aureus (MRSA). Here, we used X-ray diffraction (XRD) and inductively coupled plasma – optical emission spectroscopy (ICP-OES) and – mass spectrometry (ICP-MS) to characterize the mineralogical and chemical features of the four clay mixture samples. XRD analyses of the clay mixtures revealed minor mineralogical differences between the four samples. However, ICP analyses demonstrated that the concentrations of many elements, Fe, Co, Cu, Ni, and Zn, in particular, vary greatly across the four clay mixture leachates. Supplementation of a non-antibacterial leachate containing lower concentrations of Fe, Co, Ni, Cu, and Zn to final ion concentrations and a pH equivalent to that of the antibacterial leachate generated antibacterial activity against E. coli and MRSA, confirming the role of these ions in the antibacterial clay mixture leachates. Speciation modeling revealed increased concentrations of soluble Cu2+ and Fe2+ in the antibacterial leachates, compared to the non-antibacterial leachates, suggesting these ionic species specifically are modulating the antibacterial activity of the leachates. Finally, linear regression analyses comparing the log10 reduction in bacterial viability to the concentration of individual ion species revealed positive correlations with Zn2+ and Cu2+ and antibacterial activity, a negative correlation with Fe3+, and no correlation with pH. Together, these analyses further indicate that the ion concentration of specific species (Fe2+, Cu2+, and Zn2+) are responsible for antibacterial activity and that killing activity is not solely attributed to pH." @default.
- W1985384321 created "2016-06-24" @default.
- W1985384321 creator A5040683452 @default.
- W1985384321 creator A5047651843 @default.
- W1985384321 date "2013-05-17" @default.
- W1985384321 modified "2023-10-16" @default.
- W1985384321 title "Exchangeable Ions Are Responsible for the In Vitro Antibacterial Properties of Natural Clay Mixtures" @default.
- W1985384321 cites W1554698454 @default.
- W1985384321 cites W1981492097 @default.
- W1985384321 cites W2035497513 @default.
- W1985384321 cites W2035799638 @default.
- W1985384321 cites W2040898201 @default.
- W1985384321 cites W2050539818 @default.
- W1985384321 cites W2060445719 @default.
- W1985384321 cites W2063932638 @default.
- W1985384321 cites W2075892592 @default.
- W1985384321 cites W2090339038 @default.
- W1985384321 cites W2124386381 @default.
- W1985384321 cites W2158185109 @default.
- W1985384321 cites W2159981883 @default.
- W1985384321 cites W2169428801 @default.
- W1985384321 cites W2236754913 @default.
- W1985384321 cites W2898532680 @default.
- W1985384321 cites W58686574 @default.
- W1985384321 cites W652509803 @default.
- W1985384321 doi "https://doi.org/10.1371/journal.pone.0064068" @default.
- W1985384321 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3656846" @default.
- W1985384321 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23691149" @default.
- W1985384321 hasPublicationYear "2013" @default.
- W1985384321 type Work @default.
- W1985384321 sameAs 1985384321 @default.
- W1985384321 citedByCount "49" @default.
- W1985384321 countsByYear W19853843212013 @default.
- W1985384321 countsByYear W19853843212014 @default.
- W1985384321 countsByYear W19853843212015 @default.
- W1985384321 countsByYear W19853843212016 @default.
- W1985384321 countsByYear W19853843212017 @default.
- W1985384321 countsByYear W19853843212018 @default.
- W1985384321 countsByYear W19853843212019 @default.
- W1985384321 countsByYear W19853843212020 @default.
- W1985384321 countsByYear W19853843212021 @default.
- W1985384321 countsByYear W19853843212022 @default.
- W1985384321 countsByYear W19853843212023 @default.
- W1985384321 crossrefType "journal-article" @default.
- W1985384321 hasAuthorship W1985384321A5040683452 @default.
- W1985384321 hasAuthorship W1985384321A5047651843 @default.
- W1985384321 hasBestOaLocation W19853843211 @default.
- W1985384321 hasConcept C107872376 @default.
- W1985384321 hasConcept C121332964 @default.
- W1985384321 hasConcept C13965031 @default.
- W1985384321 hasConcept C16925390 @default.
- W1985384321 hasConcept C185592680 @default.
- W1985384321 hasConcept C2779489039 @default.
- W1985384321 hasConcept C2780104969 @default.
- W1985384321 hasConcept C523546767 @default.
- W1985384321 hasConcept C54355233 @default.
- W1985384321 hasConcept C62520636 @default.
- W1985384321 hasConcept C82706917 @default.
- W1985384321 hasConcept C86803240 @default.
- W1985384321 hasConcept C95974651 @default.
- W1985384321 hasConceptScore W1985384321C107872376 @default.
- W1985384321 hasConceptScore W1985384321C121332964 @default.
- W1985384321 hasConceptScore W1985384321C13965031 @default.
- W1985384321 hasConceptScore W1985384321C16925390 @default.
- W1985384321 hasConceptScore W1985384321C185592680 @default.
- W1985384321 hasConceptScore W1985384321C2779489039 @default.
- W1985384321 hasConceptScore W1985384321C2780104969 @default.
- W1985384321 hasConceptScore W1985384321C523546767 @default.
- W1985384321 hasConceptScore W1985384321C54355233 @default.
- W1985384321 hasConceptScore W1985384321C62520636 @default.
- W1985384321 hasConceptScore W1985384321C82706917 @default.
- W1985384321 hasConceptScore W1985384321C86803240 @default.
- W1985384321 hasConceptScore W1985384321C95974651 @default.
- W1985384321 hasIssue "5" @default.
- W1985384321 hasLocation W19853843211 @default.
- W1985384321 hasLocation W19853843212 @default.
- W1985384321 hasLocation W19853843213 @default.
- W1985384321 hasLocation W19853843214 @default.
- W1985384321 hasLocation W19853843215 @default.
- W1985384321 hasOpenAccess W1985384321 @default.
- W1985384321 hasPrimaryLocation W19853843211 @default.
- W1985384321 hasRelatedWork W1985084846 @default.
- W1985384321 hasRelatedWork W1999965726 @default.
- W1985384321 hasRelatedWork W2066008846 @default.
- W1985384321 hasRelatedWork W2081574018 @default.
- W1985384321 hasRelatedWork W2360130391 @default.
- W1985384321 hasRelatedWork W2364132695 @default.
- W1985384321 hasRelatedWork W2977724413 @default.
- W1985384321 hasRelatedWork W2993468324 @default.
- W1985384321 hasRelatedWork W3147443310 @default.
- W1985384321 hasRelatedWork W4385413210 @default.
- W1985384321 hasVolume "8" @default.
- W1985384321 isParatext "false" @default.
- W1985384321 isRetracted "false" @default.
- W1985384321 magId "1985384321" @default.
- W1985384321 workType "article" @default.