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- W1985398626 abstract "The aim of this study was to evaluate a single-institution experience in the surgical treatment of lung metastases from colorectal cancer.During a 16 years period, 42 patients underwent lung metastasectomy at the University Hospital of Nice for a total of 57 surgical interventions. Data were retrospectively collected and analysed in term of prognostic factors and long-term survival.The mean age was 64.5 years and there were 26 males and 16 females. In 36 cases lung metastasis were metachronous and the disease-free mean interval was 28.7 months. Eighteen patients had bilateral disease. In ten patients hepatic metastasectomy was done before lung resection. Forty-seven operations were performed for the 1(st) episode of lung metastasis (1 bilobectomy, 21 lobectomy, 4 segmentectomy and 38 wedge resections). Mediastinal metastatic disease was present in six patients. No patient died and the postoperative morbidity was 6.25%. Six patients needed operation for recurrent disease. Two patients died after completion pneumonectomy. Overall five and ten-year survival were 29.5 respectively 26.2%. The log-rank test identified two significant prognostic factors: radicality of metastasectomy (P =0.0066) and a disease-free interval longer than two years (P= 0.0021).Our study suggests that local control of lung metastasis can improve survival only when a radical resection can be achieved. Selection criteria need to be improved in order to avoid unnecessary lung resection in patients with high risk of recurrences. The Pet-scan should probably have a certain interest in selecting these patients." @default.
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- W1985398626 date "2004-12-01" @default.
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- W1985398626 title "Le traitement chirurgical des métastases pulmonaires des cancers colorectaux. Les indications ont-elles évoluées ?" @default.
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- W1985398626 doi "https://doi.org/10.1016/j.anchir.2004.09.013" @default.
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