FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1985399016> ?p ?o ?g. }

• W1985399016 endingPage "2191" @default.
• W1985399016 startingPage "2185" @default.
• W1985399016 abstract "The goal of this study was to determine whether postprandial hyperglycemia, induced by oral glucose loading, attenuates endothelial function in healthy subjects without diabetes and whether coadministration of vitamins C and E could prevent these postprandial changes.Epidemiologic evidence suggests that postprandial hyperglycemia, below diabetic levels, is a risk factor for cardiovascular disease. Postprandial hyperglycemia may promote atherosclerosis through endothelial dysfunction and oxidative stress.We evaluated the acute effects of oral glucose loading (75 g), alone and with vitamins C (2 g) and E (800 IU), on endothelium-dependent flow-mediated dilation (FMD) of the brachial artery, in a randomized, double-blind, placebo-controlled, crossover study of 10 healthy volunteers. Changes in the levels of markers of oxidative stress (plasma malondialdehyde and erythrocyte glutathione, glutathione peroxidase and superoxide dismutase) were also assessed.Increases in plasma glucose and insulin after glucose loading were unaffected by vitamin coadministration. With glucose loading alone, FMD fell from 6.5+/-2.2 at baseline to 5.4+/-1.7, 3.7+/-2.1*, 4.1+/-3.5* and 5.7+/-1.9% at 1, 2, 3 and 4 h (*p < 0.05 vs. 0 h). In contrast, FMD did not change significantly after glucose plus vitamins (6.4+/-1.3, 7.6+/-1.8, 7.9+/-2.7, 6.9+/-2.3, 6.9+/-1.9% at 0, 1, 2, 3 and 4 h). By two-way repeated measures analysis of variance we found a significant interaction between vitamin treatment and time (p = 0.0003), indicating that vitamins prevented the glucose-induced attenuation of FMD. Oxidative stress markers did not significantly change with glucose loading alone or with vitamins.Oral glucose loading causes an acute, transient decrease of FMD in healthy subjects without diabetes, which is prevented by vitamins C and E." @default.
• W1985399016 created "2016-06-24" @default.
• W1985399016 creator A5029721628 @default.
• W1985399016 creator A5057681522 @default.
• W1985399016 creator A5068017224 @default.
• W1985399016 creator A5081825872 @default.
• W1985399016 date "2000-12-01" @default.
• W1985399016 modified "2023-10-13" @default.
• W1985399016 title "Oral glucose loading acutely attenuates endothelium-dependent vasodilation in healthy adults without diabetes: an effect prevented by vitamins C and E" @default.
• W1985399016 cites W1965148671 @default.
• W1985399016 cites W1968388017 @default.
• W1985399016 cites W1975974235 @default.
• W1985399016 cites W1978355469 @default.
• W1985399016 cites W1982868620 @default.
• W1985399016 cites W1987226809 @default.
• W1985399016 cites W1989137854 @default.
• W1985399016 cites W1993387626 @default.
• W1985399016 cites W1995606017 @default.
• W1985399016 cites W2003803897 @default.
• W1985399016 cites W2006728188 @default.
• W1985399016 cites W2015382104 @default.
• W1985399016 cites W2016833774 @default.
• W1985399016 cites W2018720773 @default.
• W1985399016 cites W2019336823 @default.
• W1985399016 cites W2020020595 @default.
• W1985399016 cites W2020649932 @default.
• W1985399016 cites W2031417550 @default.
• W1985399016 cites W2037338720 @default.
• W1985399016 cites W2041607014 @default.
• W1985399016 cites W2044833426 @default.
• W1985399016 cites W2050856495 @default.
• W1985399016 cites W2063506869 @default.
• W1985399016 cites W2067911893 @default.
• W1985399016 cites W2069743169 @default.
• W1985399016 cites W2072902969 @default.
• W1985399016 cites W2083501039 @default.
• W1985399016 cites W2089736652 @default.
• W1985399016 cites W2090824142 @default.
• W1985399016 cites W2110301362 @default.
• W1985399016 cites W2122648697 @default.
• W1985399016 cites W2137204557 @default.
• W1985399016 cites W2137570167 @default.
• W1985399016 cites W2143401881 @default.
• W1985399016 cites W2162886683 @default.
• W1985399016 cites W2163374884 @default.
• W1985399016 cites W2165727847 @default.
• W1985399016 cites W2975364463 @default.
• W1985399016 cites W4236761262 @default.
• W1985399016 cites W4245562543 @default.
• W1985399016 doi "https://doi.org/10.1016/s0735-1097(00)00980-3" @default.
• W1985399016 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11127459" @default.
• W1985399016 hasPublicationYear "2000" @default.
• W1985399016 type Work @default.
• W1985399016 sameAs 1985399016 @default.
• W1985399016 citedByCount "314" @default.
• W1985399016 countsByYear W19853990162012 @default.
• W1985399016 countsByYear W19853990162013 @default.
• W1985399016 countsByYear W19853990162014 @default.
• W1985399016 countsByYear W19853990162015 @default.
• W1985399016 countsByYear W19853990162016 @default.
• W1985399016 countsByYear W19853990162017 @default.
• W1985399016 countsByYear W19853990162018 @default.
• W1985399016 countsByYear W19853990162019 @default.
• W1985399016 countsByYear W19853990162020 @default.
• W1985399016 countsByYear W19853990162021 @default.
• W1985399016 countsByYear W19853990162022 @default.
• W1985399016 countsByYear W19853990162023 @default.
• W1985399016 crossrefType "journal-article" @default.
• W1985399016 hasAuthorship W1985399016A5029721628 @default.
• W1985399016 hasAuthorship W1985399016A5057681522 @default.
• W1985399016 hasAuthorship W1985399016A5068017224 @default.
• W1985399016 hasAuthorship W1985399016A5081825872 @default.
• W1985399016 hasBestOaLocation W19853990161 @default.
• W1985399016 hasConcept C126322002 @default.
• W1985399016 hasConcept C134018914 @default.
• W1985399016 hasConcept C142724271 @default.
• W1985399016 hasConcept C185592680 @default.
• W1985399016 hasConcept C204787440 @default.
• W1985399016 hasConcept C27081682 @default.
• W1985399016 hasConcept C2776151105 @default.
• W1985399016 hasConcept C2776992346 @default.
• W1985399016 hasConcept C2777551382 @default.
• W1985399016 hasConcept C2777604165 @default.
• W1985399016 hasConcept C2778004101 @default.
• W1985399016 hasConcept C2778199505 @default.
• W1985399016 hasConcept C2778401633 @default.
• W1985399016 hasConcept C2780022331 @default.
• W1985399016 hasConcept C2780972559 @default.
• W1985399016 hasConcept C55493867 @default.
• W1985399016 hasConcept C555293320 @default.
• W1985399016 hasConcept C71924100 @default.
• W1985399016 hasConcept C84393581 @default.
• W1985399016 hasConcept C87813604 @default.
• W1985399016 hasConceptScore W1985399016C126322002 @default.
• W1985399016 hasConceptScore W1985399016C134018914 @default.
• W1985399016 hasConceptScore W1985399016C142724271 @default.
• W1985399016 hasConceptScore W1985399016C185592680 @default.
• W1985399016 hasConceptScore W1985399016C204787440 @default.

• next