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• W1985404997 abstract "Significance Bone morphogenetic protein (BMP) activity is regulated by prodomains. Here, structures of BMP procomplexes reveal an open-armed conformation. In contrast, the evolutionarily related, latent TGF-β1 procomplex is cross-armed. We propose that in the TGF-β and BMP family, conversion between cross-armed and open-armed conformations may regulate release and activity of the growth factor." @default.
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• W1985404997 date "2015-03-06" @default.
• W1985404997 modified "2023-10-15" @default.
• W1985404997 title "Structure of bone morphogenetic protein 9 procomplex" @default.
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• W1985404997 doi "https://doi.org/10.1073/pnas.1501303112" @default.
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