Matches in SemOpenAlex for { <https://semopenalex.org/work/W1985427819> ?p ?o ?g. }
Showing items 1 to 49 of
49
with 100 items per page.
- W1985427819 endingPage "1956" @default.
- W1985427819 startingPage "1955" @default.
- W1985427819 abstract "It has been about 25 years since the initial AIDS case reports and 10 years since the first reports suggesting that combination highly active antiretroviral therapy (HAART) can potently and perhaps indefinitely suppress HIV replication. During that time several widely accepted conclusions about treatment have emerged. First HAART works. When the right drugs are given to a motivated and highly adherent patient HIV replication is suppressed indefinitely. Second most if not all antiretroviral drugs have short-term and long-term side-effects. These side-effects include chronic gastrointestinal symptoms low-level malaise mood changes lipid abnormalities accelerated atherosclerosis and peripheral fat-wasting (lipoatrophy). Third life-long adherence to even a well-tolerated regimen can be challenging for most patients. Pill fatigue eventually sets in for many patients leading to a lower quality of life and an increased risk of nonadherence and eventual treatment failure. Fourth antiretroviral therapy and its monitoring are expensive. First-line regimens range from US$5000 to $10 000 a year in resource-rich countries and from $300 to over $1000 a year in resource-poor regions. Second-line regimens are even more expensive. (excerpt)" @default.
- W1985427819 created "2016-06-24" @default.
- W1985427819 creator A5063704053 @default.
- W1985427819 date "2006-06-01" @default.
- W1985427819 modified "2023-09-27" @default.
- W1985427819 title "The risk of treatment versus the risk of HIV replication" @default.
- W1985427819 cites W2041929815 @default.
- W1985427819 cites W2108719992 @default.
- W1985427819 cites W2117150863 @default.
- W1985427819 cites W2129630483 @default.
- W1985427819 cites W2183940924 @default.
- W1985427819 cites W2329393410 @default.
- W1985427819 doi "https://doi.org/10.1016/s0140-6736(06)68857-0" @default.
- W1985427819 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16782465" @default.
- W1985427819 hasPublicationYear "2006" @default.
- W1985427819 type Work @default.
- W1985427819 sameAs 1985427819 @default.
- W1985427819 citedByCount "8" @default.
- W1985427819 countsByYear W19854278192012 @default.
- W1985427819 crossrefType "journal-article" @default.
- W1985427819 hasAuthorship W1985427819A5063704053 @default.
- W1985427819 hasConcept C12590798 @default.
- W1985427819 hasConcept C159047783 @default.
- W1985427819 hasConcept C71924100 @default.
- W1985427819 hasConceptScore W1985427819C12590798 @default.
- W1985427819 hasConceptScore W1985427819C159047783 @default.
- W1985427819 hasConceptScore W1985427819C71924100 @default.
- W1985427819 hasIssue "9527" @default.
- W1985427819 hasLocation W19854278191 @default.
- W1985427819 hasLocation W19854278192 @default.
- W1985427819 hasOpenAccess W1985427819 @default.
- W1985427819 hasPrimaryLocation W19854278191 @default.
- W1985427819 hasRelatedWork W1964748913 @default.
- W1985427819 hasRelatedWork W1971051337 @default.
- W1985427819 hasRelatedWork W2018150492 @default.
- W1985427819 hasRelatedWork W2049234127 @default.
- W1985427819 hasRelatedWork W2056447737 @default.
- W1985427819 hasRelatedWork W2078121669 @default.
- W1985427819 hasRelatedWork W2098836292 @default.
- W1985427819 hasRelatedWork W2143613583 @default.
- W1985427819 hasRelatedWork W3043946219 @default.
- W1985427819 hasRelatedWork W4241372183 @default.
- W1985427819 hasVolume "367" @default.
- W1985427819 isParatext "false" @default.
- W1985427819 isRetracted "false" @default.
- W1985427819 magId "1985427819" @default.
- W1985427819 workType "article" @default.