FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1985477620> ?p ?o ?g. }

• W1985477620 endingPage "237" @default.
• W1985477620 startingPage "232" @default.
• W1985477620 abstract "Background Peak exercise capacity improves early after orthotopic cardiac transplantation. However, the physiological response to exercise remains abnormal, with a reduced rate of heart rate (HR) rise and reductions in peak exercise HR and the increment in HR from rest to peak exercise. This chronotropic incompetence is due in large part to cardiac denervation. If reinnervation occurs after transplantation, it might result in an improvement in both chronotropic responsiveness and maximal exercise capacity. We therefore hypothesized that the chronotropic response to exercise and maximal exercise capacity would improve with time after transplantation. Methods and Results Peak symptom-limited cardiopulmonary exercise tests performed in 57 clinically stable cardiac transplant recipients (mean age, 45±2 years) serially for up to 5 years after transplantation and in 33 control subjects without heart disease were analyzed retrospectively. Pretransplantation exercise tests were also performed in 41 patients an average of 4.7±0.6 months before transplantation. At 1 year after transplantation, peak oxygen consumption was 16.6±0.9 mL·kg −1 ·min −1 , reflecting a 43% increase versus pretransplantation. Nevertheless, compared with control subjects, maximal exercise capacity and the HR response to exercise were subnormal in transplant recipients. There were no further increases in peak exercise capacity, peak exercise HR, or the peak increment in HR with exercise up to 5 years after transplantation. Conclusions One year after cardiac transplantation, peak exercise capacity and chronotropic responsiveness are subnormal. There is no further improvement in peak exercise capacity or chronotropic responsiveness as late as 5 years after transplantation. These data indicate that with regard to chronotropic responsiveness, functionally significant cardiac reinnervation does not occur between the first and fifth years after transplantation." @default.
• W1985477620 created "2016-06-24" @default.
• W1985477620 creator A5019935820 @default.
• W1985477620 creator A5031837459 @default.
• W1985477620 creator A5088310205 @default.
• W1985477620 date "1997-07-01" @default.
• W1985477620 modified "2023-09-23" @default.
• W1985477620 title "Long-term Sequential Changes in Exercise Capacity and Chronotropic Responsiveness After Cardiac Transplantation" @default.
• W1985477620 cites W1970677949 @default.
• W1985477620 cites W1979318115 @default.
• W1985477620 cites W1989768356 @default.
• W1985477620 cites W1996683481 @default.
• W1985477620 cites W1997271863 @default.
• W1985477620 cites W2011850787 @default.
• W1985477620 cites W2016787867 @default.
• W1985477620 cites W2036404321 @default.
• W1985477620 cites W2053483835 @default.
• W1985477620 cites W2056084784 @default.
• W1985477620 cites W2060275689 @default.
• W1985477620 cites W2063902214 @default.
• W1985477620 cites W2067329441 @default.
• W1985477620 cites W2111730786 @default.
• W1985477620 cites W2124383642 @default.
• W1985477620 cites W2165181695 @default.
• W1985477620 cites W2218308347 @default.
• W1985477620 cites W2339188771 @default.
• W1985477620 cites W2438204802 @default.
• W1985477620 cites W2472881723 @default.
• W1985477620 doi "https://doi.org/10.1161/01.cir.96.1.232" @default.
• W1985477620 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9236439" @default.
• W1985477620 hasPublicationYear "1997" @default.
• W1985477620 type Work @default.
• W1985477620 sameAs 1985477620 @default.
• W1985477620 citedByCount "102" @default.
• W1985477620 countsByYear W19854776202012 @default.
• W1985477620 countsByYear W19854776202013 @default.
• W1985477620 countsByYear W19854776202015 @default.
• W1985477620 countsByYear W19854776202016 @default.
• W1985477620 countsByYear W19854776202017 @default.
• W1985477620 countsByYear W19854776202018 @default.
• W1985477620 countsByYear W19854776202019 @default.
• W1985477620 countsByYear W19854776202020 @default.
• W1985477620 countsByYear W19854776202021 @default.
• W1985477620 countsByYear W19854776202023 @default.
• W1985477620 crossrefType "journal-article" @default.
• W1985477620 hasAuthorship W1985477620A5019935820 @default.
• W1985477620 hasAuthorship W1985477620A5031837459 @default.
• W1985477620 hasAuthorship W1985477620A5088310205 @default.
• W1985477620 hasConcept C126322002 @default.
• W1985477620 hasConcept C158328960 @default.
• W1985477620 hasConcept C164705383 @default.
• W1985477620 hasConcept C181588539 @default.
• W1985477620 hasConcept C196310339 @default.
• W1985477620 hasConcept C2777953023 @default.
• W1985477620 hasConcept C2778849806 @default.
• W1985477620 hasConcept C2911091166 @default.
• W1985477620 hasConcept C71924100 @default.
• W1985477620 hasConcept C84393581 @default.
• W1985477620 hasConceptScore W1985477620C126322002 @default.
• W1985477620 hasConceptScore W1985477620C158328960 @default.
• W1985477620 hasConceptScore W1985477620C164705383 @default.
• W1985477620 hasConceptScore W1985477620C181588539 @default.
• W1985477620 hasConceptScore W1985477620C196310339 @default.
• W1985477620 hasConceptScore W1985477620C2777953023 @default.
• W1985477620 hasConceptScore W1985477620C2778849806 @default.
• W1985477620 hasConceptScore W1985477620C2911091166 @default.
• W1985477620 hasConceptScore W1985477620C71924100 @default.
• W1985477620 hasConceptScore W1985477620C84393581 @default.
• W1985477620 hasIssue "1" @default.
• W1985477620 hasLocation W19854776201 @default.
• W1985477620 hasLocation W19854776202 @default.
• W1985477620 hasOpenAccess W1985477620 @default.
• W1985477620 hasPrimaryLocation W19854776201 @default.
• W1985477620 hasRelatedWork W1985477620 @default.
• W1985477620 hasRelatedWork W2013910194 @default.
• W1985477620 hasRelatedWork W2100140594 @default.
• W1985477620 hasRelatedWork W2132084610 @default.
• W1985477620 hasRelatedWork W2138751725 @default.
• W1985477620 hasRelatedWork W2149553758 @default.
• W1985477620 hasRelatedWork W2177232863 @default.
• W1985477620 hasRelatedWork W2408771066 @default.
• W1985477620 hasRelatedWork W2468482135 @default.
• W1985477620 hasRelatedWork W2967606589 @default.
• W1985477620 hasVolume "96" @default.
• W1985477620 isParatext "false" @default.
• W1985477620 isRetracted "false" @default.
• W1985477620 magId "1985477620" @default.
• W1985477620 workType "article" @default.