FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1985483414> ?p ?o ?g. }

• W1985483414 endingPage "280" @default.
• W1985483414 startingPage "274" @default.
• W1985483414 abstract "Abstract Replication has been difficult to achieve in linkage studies of psychiatric disease. Linkage studies of panic disorder have indicated regions of interest on chromosomes 1q, 2p, 2q, 3, 7, 9, 11, 12q13, 12q23, and 15. Few regions have been implicated in more than one study. We examine two samples, the Iowa (IA) and the Columba panic disorder families. We use the fuzzy‐clustering method presented by Kaabi et al. [Kaabi et al. (2006); Am J Hum Genet 78: 543–553] to summarize liability to panic disorder, agoraphobia, simple phobia, and social phobia. Kaabi et al. applied this method to the Yale panic disorder linkage families and found evidence of linkage to chromosomes 4q21, 4q32, 7p, and 8. When we apply the same method to the IA families, we obtain overlapping evidence of linkage to chromosomes 4q21 and 7p. Additionally, we find evidence of linkage on chromosomes 1, 5, 6, 16, and 22. The Columbia (CO) data does not indicate linkage to any of the Kaabi et al. peaks, instead implicating chromosomes 2 and 22q11 (2 Mb from COMT). There is some evidence of overlapping linkage between the IA and CO datasets on chromosomes 1 and 14. While use of fuzzy clustering has not produced complete concordance across datasets, it has produced more than previously seen in analyses of panic disorder proper. We conclude that chromosomes 4q21 and 7p should be considered strong candidate regions for panic and fear‐associated anxiety disorder loci. More generally, this suggests that analyses including multiple aspects of psychopathology may lead to greater consistency across datasets. © 2012 Wiley Periodicals, Inc." @default.
• W1985483414 created "2016-06-24" @default.
• W1985483414 creator A5018262839 @default.
• W1985483414 creator A5023304607 @default.
• W1985483414 creator A5024715287 @default.
• W1985483414 creator A5032997650 @default.
• W1985483414 creator A5052802548 @default.
• W1985483414 creator A5080851216 @default.
• W1985483414 creator A5085226622 @default.
• W1985483414 creator A5091820416 @default.
• W1985483414 date "2012-01-17" @default.
• W1985483414 modified "2023-10-17" @default.
• W1985483414 title "Multivariate analysis of anxiety disorders yields further evidence of linkage to chromosomes 4q21 and 7p in panic disorder families" @default.
• W1985483414 cites W1968864839 @default.
• W1985483414 cites W1975670257 @default.
• W1985483414 cites W1976741643 @default.
• W1985483414 cites W1976810833 @default.
• W1985483414 cites W1976872972 @default.
• W1985483414 cites W1977104259 @default.
• W1985483414 cites W1981879624 @default.
• W1985483414 cites W1985318959 @default.
• W1985483414 cites W1988834331 @default.
• W1985483414 cites W1995252240 @default.
• W1985483414 cites W1998130442 @default.
• W1985483414 cites W2011907831 @default.
• W1985483414 cites W2013935385 @default.
• W1985483414 cites W2018694953 @default.
• W1985483414 cites W2027460621 @default.
• W1985483414 cites W2033242710 @default.
• W1985483414 cites W2038279554 @default.
• W1985483414 cites W2059320845 @default.
• W1985483414 cites W2059403298 @default.
• W1985483414 cites W2066687358 @default.
• W1985483414 cites W2073544062 @default.
• W1985483414 cites W2078581693 @default.
• W1985483414 cites W2081505479 @default.
• W1985483414 cites W2084877590 @default.
• W1985483414 cites W2090234826 @default.
• W1985483414 cites W2093396350 @default.
• W1985483414 cites W2101177381 @default.
• W1985483414 cites W2110747672 @default.
• W1985483414 cites W2131052408 @default.
• W1985483414 cites W2136033660 @default.
• W1985483414 cites W2142146651 @default.
• W1985483414 cites W2147784213 @default.
• W1985483414 cites W2726535572 @default.
• W1985483414 cites W4244810488 @default.
• W1985483414 doi "https://doi.org/10.1002/ajmg.b.32024" @default.
• W1985483414 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3306232" @default.
• W1985483414 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22253211" @default.
• W1985483414 hasPublicationYear "2012" @default.
• W1985483414 type Work @default.
• W1985483414 sameAs 1985483414 @default.
• W1985483414 citedByCount "6" @default.
• W1985483414 countsByYear W19854834142013 @default.
• W1985483414 countsByYear W19854834142014 @default.
• W1985483414 countsByYear W19854834142015 @default.
• W1985483414 countsByYear W19854834142018 @default.
• W1985483414 crossrefType "journal-article" @default.
• W1985483414 hasAuthorship W1985483414A5018262839 @default.
• W1985483414 hasAuthorship W1985483414A5023304607 @default.
• W1985483414 hasAuthorship W1985483414A5024715287 @default.
• W1985483414 hasAuthorship W1985483414A5032997650 @default.
• W1985483414 hasAuthorship W1985483414A5052802548 @default.
• W1985483414 hasAuthorship W1985483414A5080851216 @default.
• W1985483414 hasAuthorship W1985483414A5085226622 @default.
• W1985483414 hasAuthorship W1985483414A5091820416 @default.
• W1985483414 hasBestOaLocation W19854834142 @default.
• W1985483414 hasConcept C104317684 @default.
• W1985483414 hasConcept C118552586 @default.
• W1985483414 hasConcept C142870003 @default.
• W1985483414 hasConcept C15744967 @default.
• W1985483414 hasConcept C2776317618 @default.
• W1985483414 hasConcept C2777529043 @default.
• W1985483414 hasConcept C2778678127 @default.
• W1985483414 hasConcept C2780712732 @default.
• W1985483414 hasConcept C31266012 @default.
• W1985483414 hasConcept C54355233 @default.
• W1985483414 hasConcept C558461103 @default.
• W1985483414 hasConcept C86803240 @default.
• W1985483414 hasConceptScore W1985483414C104317684 @default.
• W1985483414 hasConceptScore W1985483414C118552586 @default.
• W1985483414 hasConceptScore W1985483414C142870003 @default.
• W1985483414 hasConceptScore W1985483414C15744967 @default.
• W1985483414 hasConceptScore W1985483414C2776317618 @default.
• W1985483414 hasConceptScore W1985483414C2777529043 @default.
• W1985483414 hasConceptScore W1985483414C2778678127 @default.
• W1985483414 hasConceptScore W1985483414C2780712732 @default.
• W1985483414 hasConceptScore W1985483414C31266012 @default.
• W1985483414 hasConceptScore W1985483414C54355233 @default.
• W1985483414 hasConceptScore W1985483414C558461103 @default.
• W1985483414 hasConceptScore W1985483414C86803240 @default.
• W1985483414 hasIssue "3" @default.
• W1985483414 hasLocation W19854834141 @default.
• W1985483414 hasLocation W19854834142 @default.
• W1985483414 hasLocation W19854834143 @default.
• W1985483414 hasLocation W19854834144 @default.
• W1985483414 hasLocation W19854834145 @default.

• next