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Matches in SemOpenAlex for { <https://semopenalex.org/work/W1985508970> ?p ?o ?g. }

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• W1985508970 abstract "A new series of 1β-methyl carbapenems, in which a disubstituted-aminothiocarbonylthio moiety was attached to the C-2 position of the carbapenem nucleus, were prepared and evaluated for anti-MRSA activity. These derivatives showed good in vitro antibacterial activity against high-level MRSA, and the finding of good affinity for PBP-2′ supported these results. Some of the compounds having favorable protein-binding affinity showed excellent in vivo anti-MRSA activity." @default.
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• W1985508970 date "1998-07-01" @default.
• W1985508970 modified "2023-10-17" @default.
• W1985508970 title "Novel dithiocarbamate carbapenems with anti-MRSA activity" @default.
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• W1985508970 doi "https://doi.org/10.1016/s0968-0896(98)00069-8" @default.
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