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Matches in SemOpenAlex for { <https://semopenalex.org/work/W1985525186> ?p ?o ?g. }

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• W1985525186 abstract "Intracellular recordings in vivo from noradrenergic neurons in the rat locus coeruleus showed that membrane potential was hyperpolarized by the administration of clonidine (an alpha 2-adrenoceptor agonist) or after a burst of spikes evoked by intracellular pulses; both types of hyperpolarization were associated with a decrease in membrane input resistance, and both could be blocked by the alpha 2-adrenoceptor antagonist piperoxane. These results suggest that a hyperpolarization of membrane potential mediated by an alpha 2-adrenoceptor underlies both clonidine- and activation-induced inhibition of locus coeruleus cell firing." @default.
• W1985525186 created "2016-06-24" @default.
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• W1985525186 date "1982-03-12" @default.
• W1985525186 modified "2023-09-27" @default.
• W1985525186 title "α ₂ -Adrenoceptor-Mediated Hyperpolarization of Locus Coeruleus Neurons: Intracellular Studies in Vivo" @default.
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• W1985525186 doi "https://doi.org/10.1126/science.6278591" @default.
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• W1985525186 hasPublicationYear "1982" @default.
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